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Science 15 July 1988:
Vol. 241. no. 4863, pp. 346 - 349
DOI: 10.1126/science.241.4863.346
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Articles

Naturally Occurring Auxin Transport Regulators

MARK JACOBS 1 and PHILIP H. RUBERY 1

1 Department of Biochemistry, University of Cambridge, Cambridge, CB2 IQW England, United Kingdom.

The process of polar auxin transport, central to a plant's auxin relations, can be inhibited by a group of synthetic compounds that apparently act by binding to a plasma membrane protein known as the naphthylphthalamic acid (NPA) receptor. No endogenous ligand to the NPA receptor, capable of affecting polar auxin transport in plants, has yet been found. It is now shown that a group of flavonoids-including quercetin, apigenin, and kaempferol—can specifically compete with [3H]NPA for binding to its receptor and can perturb auxin transport in a variety of plant tissues and transport systems in a manner closely paralleling the action of synthetic transport inhibitors. Because the active flavonoids are widely distributed in the plant kingdom and exert their effects at micromolar concentrations approximating likely endogenous levels, they may act as natural auxin transport regulators in plants.

Submitted on October 22, 1987
Accepted on May 17, 1988


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Science. ISSN 0036-8075 (print), 1095-9203 (online)