Science 26 August 1988: Vol. 241. no. 4869, pp. 1077 - 1080 DOI: 10.1126/science.3413476

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Articles

Sequencing by Cyclic Ligation and Cleavage (CycLiC) directly on a microarray captured template.

K. U. Mir, H. Qi, O. Salata, and G. Scozzafava (2008)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Genotyping {beta}-Globin Gene Mutations on Copolymer-Coated Glass Slides with the Ligation Detection Reaction.

S. Battistella, F. Damin, M. Chiari, K. Delgrosso, S. Surrey, P. Fortina, M. Ferrari, and L. Cremonesi (2008)
Clin. Chem. 54, 1657-1663
 |  Abstract »  |  Full Text »  |  PDF »

In Situ Detection of Anaplasma spp. by DNA Target-Primed Rolling-Circle Amplification of a Padlock Probe and Intracellular Colocalization with Immunofluorescently Labeled Host Cell von Willebrand Factor.

H. L. Wamsley and A. F. Barbet (2008)
J. Clin. Microbiol. 46, 2314-2319
 |  Abstract »  |  Full Text »  |  PDF »

A ligation assay for multiplex analysis of CpG methylation using bisulfite-treated DNA.

C. Dahl and P. Guldberg (2007)
Nucleic Acids Res. 35, e144
 |  Abstract »  |  Full Text »  |  PDF »

Development and Evaluation of an Oligonucleotide Ligation Assay for Detection of Drug Resistance-Associated Mutations in the Human Immunodeficiency Virus Type 2 pol Gene.

S. Jallow, S. Kaye, M. Schutten, E. Brandin, J. Albert, S. J. McConkey, T. Corrah, H. Whittle, G. Vanham, S. Rowland-Jones, et al. (2007)
J. Clin. Microbiol. 45, 1565-1571
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Detection of Point Mutations Conferring Resistance to Fluoroquinolone in gyrA of Helicobacter pylori by Allele-Specific PCR.

T. Nishizawa, H. Suzuki, A. Umezawa, H. Muraoka, E. Iwasaki, T. Masaoka, I. Kobayashi, and T. Hibi (2007)
J. Clin. Microbiol. 45, 303-305
 |  Abstract »  |  Full Text »  |  PDF »

Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements.

J. Dostie, T. A. Richmond, R. A. Arnaout, R. R. Selzer, W. L. Lee, T. A. Honan, E. D. Rubio, A. Krumm, J. Lamb, C. Nusbaum, et al. (2006)
Genome Res. 16, 1299-1309
 |  Abstract »  |  Full Text »  |  PDF »

Homogeneous point mutation detection by quantum dot-mediated two-color fluorescence coincidence analysis.

H.-C. Yeh, Y.-P. Ho, I.-M. Shih, and T.-H. Wang (2006)
Nucleic Acids Res. 34, e35
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Use of Ramification Amplification Assay for Detection of Escherichia coli O157:H7 and Other E. coli Shiga Toxin-Producing Strains.

F. Li, C. Zhao, W. Zhang, S. Cui, J. Meng, J. Wu, and D. Y. Zhang (2005)
J. Clin. Microbiol. 43, 6086-6090
 |  Abstract »  |  Full Text »  |  PDF »

The Effect of Polymorphisms in the Enhancer of split Gene Complex on Bristle Number Variation in a Large Wild-Caught Cohort of Drosophila melanogaster.

S. J. Macdonald, T. Pastinen, and A. D. Long (2005)
Genetics 171, 1741-1756
 |  Abstract »  |  Full Text »  |  PDF »

A colorimetric method for point mutation detection using high-fidelity DNA ligase.

J. Li, X. Chu, Y. Liu, J.-H. Jiang, Z. He, Z. Zhang, G. Shen, and R.-Q. Yu (2005)
Nucleic Acids Res. 33, e168
 |  Abstract »  |  Full Text »  |  PDF »

Detection of BRAF mutations in colorectal tumours and peritoneal washings using a mismatch ligation assay.

K Busby and A Morris (2005)
J. Clin. Pathol. 58, 372-375
 |  Abstract »  |  Full Text »  |  PDF »

Competitive enzymatic reaction to control allele-specific extensions.

E. Hultin, M. Kaller, A. Ahmadian, and J. Lundeberg (2005)
Nucleic Acids Res. 33, e48
 |  Abstract »  |  Full Text »  |  PDF »

SNP identification in unamplified human genomic DNA with gold nanoparticle probes.

Y. P. Bao, M. Huber, T.-F. Wei, S. S. Marla, J. J. Storhoff, and U. R. Müller (2005)
Nucleic Acids Res. 33, e15
 |  Abstract »  |  Full Text »  |  PDF »

Multiplex Assays with Fluorescent Microbead Readout: A Powerful Tool for Mutation Detection.

L. A. Ugozzoli (2004)
Clin. Chem. 50, 1963-1965
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A novel method of identifying genetic mutations using an electrochemical DNA array.

J. Wakai, A. Takagi, M. Nakayama, T. Miya, T. Miyahara, T. Iwanaga, S. Takenaka, Y. Ikeda, and M. Amano (2004)
Nucleic Acids Res. 32, e141
 |  Abstract »  |  Full Text »  |  PDF »

DNA ligases ensure fidelity by interrogating minor groove contacts.

P. Liu, A. Burdzy, and L. C. Sowers (2004)
Nucleic Acids Res. 32, 4503-4511
 |  Abstract »  |  Full Text »  |  PDF »

Diversity Arrays Technology (DArT) for whole-genome profiling of barley.

P. Wenzl, J. Carling, D. Kudrna, D. Jaccoud, E. Huttner, A. Kleinhofs, and A. Kilian (2004)
PNAS 101, 9915-9920
 |  Abstract »  |  Full Text »  |  PDF »

Real-Time Gap Ligase Chain Reaction: A Rapid Semiquantitative Assay for Detecting p53 Mutation at Low Levels in Surgical Margins and Lymph Nodes from Resected Lung and Head and Neck Tumors.

S. V. Harden, D. C. Thomas, N. Benoit, K. Minhas, W. H. Westra, J. A. Califano, W. Koch, and D. Sidransky (2004)
Clin. Cancer Res. 10, 2379-2385
 |  Abstract »  |  Full Text »  |  PDF »

A third base pair for the polymerase chain reaction: inserting isoC and isoG.

S. C. Johnson, C. B. Sherrill, D. J. Marshall, M. J. Moser, and J. R. Prudent (2004)
Nucleic Acids Res. 32, 1937-1941
 |  Abstract »  |  Full Text »  |  PDF »

SNPWaveTM: a flexible multiplexed SNP genotyping technology.

M. J. T. van Eijk, J. L. N. Broekhof, H. J. A. van der Poel, R. C. J. Hogers, H. Schneiders, J. Kamerbeek, E. Verstege, J. W. van Aart, H. Geerlings, J. B. Buntjer, et al. (2004)
Nucleic Acids Res. 32, e47
 |  Abstract »  |  Full Text »  |  PDF »

Ligase-mediated construction of branched DNA strands: a novel DNA joining activity catalyzed by T4 DNA ligase.

M. Mendel-Hartvig, A. Kumar, and U. Landegren (2004)
Nucleic Acids Res. 32, e2
 |  Abstract »  |  Full Text »  |  PDF »

No Evidence for an Association Between Common Nonsynonymous Polymorphisms in Delta and Bristle Number Variation in Natural and Laboratory Populations of Drosophila melanogaster.

A. Genissel, T. Pastinen, A. Dowell, T. F. C. Mackay, and A. D. Long (2004)
Genetics 166, 291-306
 |  Abstract »  |  Full Text »  |  PDF »

Real-time monitoring of nucleic acid ligation in homogenous solutions using molecular beacons.

Z. Tang, K. Wang, W. Tan, J. Li, L. Liu, Q. Guo, X. Meng, C. Ma, and S. Huang (2003)
Nucleic Acids Res. 31, e148
 |  Abstract »  |  Full Text »  |  PDF »

Viral and microbial genotyping by a combination of multiplex competitive hybridization and specific extension followed by hybridization to generic tag arrays.

B. Gharizadeh, M. Kaller, P. Nyren, A. Andersson, M. Uhlen, J. Lundeberg, and A. Ahmadian (2003)
Nucleic Acids Res. 31, e146
 |  Abstract »  |  Full Text »  |  PDF »

Canonical nucleosides can be utilized by T4 DNA ligase as universal template bases at ligation junctions.

R. C. Alexander, A. K. Johnson, J. A. Thorpe, T. Gevedon, and S. M. Testa (2003)
Nucleic Acids Res. 31, 3208-3216
 |  Abstract »  |  Full Text »  |  PDF »

Novel Fluorescent Ligase Detection Reaction and Flow Cytometric Analysis of SYT-SSX Fusions in Synovial Sarcoma.

R. Gaffney, A. Chakerian, J. X. O'Connell, J. Mathers, K. Garner, N. Joste, and D. S. Viswanatha (2003)
J. Mol. Diagn. 5, 127-135
 |  Abstract »  |  Full Text »  |  PDF »

The observed human sperm mutation frequency cannot explain the achondroplasia paternal age effect.

I. Tiemann-Boege, W. Navidi, R. Grewal, D. Cohn, B. Eskenazi, A. J. Wyrobek, and N. Arnheim (2002)
PNAS 99, 14952-14957
 |  Abstract »  |  Full Text »  |  PDF »

An orthogonal oligonucleotide protecting group strategy that enables assembly of repetitive or highly structured DNAs.

U. M. Lindstrom and E. T. Kool (2002)
Nucleic Acids Res. 30, e101
 |  Abstract »  |  Full Text »  |  PDF »

SNP typing by apyrase-mediated allele-specific primer extension on DNA microarrays.

D. O'Meara, A. Ahmadian, J. Odeberg, and J. Lundeberg (2002)
Nucleic Acids Res. 30, e75
 |  Abstract »  |  Full Text »  |  PDF »

Single nucleotide polymorphism seeking long term association with complex disease.

B. W. Kirk, M. Feinsod, R. Favis, R. M. Kliman, and F. Barany (2002)
Nucleic Acids Res. 30, 3295-3311
 |  Abstract »  |  Full Text »  |  PDF »

Competitive Amplification and Unspecific Amplification in Polymerase Chain Reaction with Confronting Two-Pair Primers.

N. Hamajima, T. Saito, K. Matsuo, and K. Tajima (2002)
J. Mol. Diagn. 4, 103-107
 |  Abstract »  |  Full Text »  |  PDF »

Rapid and Sensitive Oligonucleotide Ligation Assay for Detection of Mutations in Human Immunodeficiency Virus Type 1 Associated with High-Level Resistance to Protease Inhibitors.

I. A. Beck, M. Mahalanabis, G. Pepper, A. Wright, S. Hamilton, E. Langston, and L. M. Frenkel (2002)
J. Clin. Microbiol. 40, 1413-1419
 |  Abstract »  |  Full Text »  |  PDF »

Single nucleotide polymorphism detection by combinatorial fluorescence energy transfer tags and biotinylated dideoxynucleotides.

A. K. Tong and J. Ju (2002)
Nucleic Acids Res. 30, e19
 |  Abstract »  |  Full Text »  |  PDF »

Genetic screening using the colour change of a PNA-DNA hybrid-binding cyanine dye.

L. M. Wilhelmsson, B. Norden, K. Mukherjee, M. T. Dulay, and R. N. Zare (2002)
Nucleic Acids Res. 30, e3
 |  Abstract »  |  Full Text »  |  PDF »

Detection of Chlamydia trachomatis by Isothermal Ramification Amplification Method: a Feasibility Study.

W. Zhang, M. Cohenford, B. Lentrichia, H. D. Isenberg, E. Simson, H. Li, J. Yi, and D. Y. Zhang (2002)
J. Clin. Microbiol. 40, 128-132
 |  Abstract »  |  Full Text »  |  PDF »

L-RCA (ligation-rolling circle amplification): a general method for genotyping of single nucleotide polymorphisms (SNPs).

X. Qi, S. Bakht, K. M. Devos, M. D. Gale, and A. Osbourn (2001)
Nucleic Acids Res. 29, e116
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of single nucleotide polymorphisms with solid phase invasive cleavage reactions.

P. Wilkins Stevens, J. G. Hall, V. Lyamichev, B. P. Neri, M. Lu, L. Wang, L. M. Smith, and D. M. Kelso (2001)
Nucleic Acids Res. 29, e77
 |  Abstract »  |  Full Text »  |  PDF »

RNA-templated DNA ligation for transcript analysis.

M. Nilsson, D.-O. Antson, G. Barbany, and U. Landegren (2001)
Nucleic Acids Res. 29, 578-581
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Assays for the Diagnosis of Minimal Residual Head-and-Neck Cancer: Methods, Reliability, Pitfalls, and Solutions.

V. M. M. van Houten, M. P. Tabor, M. W. M. van den Brekel, F. Denkers, R. G. A. Wishaupt, J. A. Kummer, G. B. Snow, and R. H. Brakenhoff (2000)
Clin. Cancer Res. 6, 3803-3816
 |  Abstract »  |  Full Text »

Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing.

A. Alderborn, A. Kristofferson, and U. Hammerling (2000)
Genome Res. 10, 1249-1258
 |  Abstract »  |  Full Text »

PCR-generated padlock probes detect single nucleotide variation in genomic DNA.

D.-O. Antson, A. Isaksson, U. Landegren, and M. Nilsson (2000)
Nucleic Acids Res. 28, e58
 |  Abstract »  |  Full Text »  |  PDF »

Detection of the Finnish-Type Congenital Nephrotic Syndrome by Restriction Fragment Length Polymorphism and Dual-Color Oligonucleotide Ligation Assays.

E.-L. Romppanen and I. Mononen (2000)
Clin. Chem. 46, 811-816
 |  Abstract »  |  Full Text »  |  PDF »

A Mutation in PRKAG3 Associated with Excess Glycogen Content in Pig Skeletal Muscle.

D. Milan, J. Jeon, C. Looft, V. Amarger, A. Robic, M. Thelander, C. Rogel-Gaillard, S. Paul, N. Iannuccelli, L. Rask, et al. (2000)
Science 288, 1248-1251
 |  Abstract »  |  Full Text »

A Microsphere-Based Assay for Multiplexed Single Nucleotide Polymorphism Analysis Using Single Base Chain Extension.

J. Chen, M. A. Iannone, M.-S. Li, J. D. Taylor, P. Rivers, A. J. Nelsen, K. A. Slentz-Kesler, A. Roses, and M. P. Weiner (2000)
Genome Res. 10, 549-557
 |  Abstract »  |  Full Text »

Optimised ligation of oligonucleotides by thermal ligases: comparison of Thermus scotoductus and Rhodothermus marinus DNA ligases to other thermophilic ligases.

J. N. Housby, S. H. Thorbjarnardottir, Z. O. Jonsson, and E. M. Southern (2000)
Nucleic Acids Res. 28, e10
 |  Abstract »  |  Full Text »  |  PDF »

PCR-Oligonucleotide Ligation Assay from Dried Blood Spots.

E.-L. Romppanen and I. Mononen (1999)
Clin. Chem. 45, 2022-2025
 |  Full Text »  |  PDF »

Accuracy of Genotyping of Single-Nucleotide Polymorphisms by PCR-ELISA Allele-specific Oligonucleotide Hybridization Typing and by Amplification Refractory Mutation System.

J. C. Knight, W. McGuire, M. M. Kortok, and D. Kwiatkowski (1999)
Clin. Chem. 45, 1860-1863
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Fine-mapping of quantitative trait loci by identity by descent in outbred populations: Application to milk production in dairy cattle.

J. Riquet, W. Coppieters, N. Cambisano, J.-J. Arranz, P. Berzi, S. K. Davis, B. Grisart, F. Farnir, L. Karim, M. Mni, et al. (1999)
PNAS 96, 9252-9257
 |  Abstract »  |  Full Text »  |  PDF »

The Frequency of an Inactivating Point Mutation (566C->T) of the Human Follicle-Stimulating Hormone Receptor Gene in Four Populations Using Allele-Specific Hybridization and Time-Resolved Fluorometry.

M. Jiang, K. Aittomäki, C. Nilsson, P. Pakarinen, A. Iitiä, T. Torresani, H. Simonsen, V. Goh, K. Pettersson, A. de la Chapelle, et al. (1998)
J. Clin. Endocrinol. Metab. 83, 4338-4343
 |  Abstract »  |  Full Text »

Molecular Diagnosis of Finnish Type Infantile Neuronal Ceroid Lipofuscinosis by Restriction Fragment Length Polymorphism and Oligonucleotide Ligation Assay.

E.-L. Romppanen, P. Valtonen, T. Mononen, and I. Mononen (1998)
Clin. Chem. 44, 2373-2376
 |  Full Text »  |  PDF »

Reading Bits of Genetic Information: Methods for Single-Nucleotide Polymorphism Analysis.

U. Landegren, M. Nilsson, and P.-Y. Kwok (1998)
Genome Res. 8, 769-776
 |  Full Text »

Cloning of Two Novel Growth Hormone Transcripts Expressed in Human Placenta.

C. L. Boguszewski, P.-A. Svensson, T. Jansson, R. Clark, L. M. S. Carlsson, and B. Carlsson (1998)
J. Clin. Endocrinol. Metab. 83, 2878-2885
 |  Abstract »  |  Full Text »

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome.

D. G. Wang, J. Fan, C. Siao, A. Berno, P. Young, R. Sapolsky, G. Ghandour, N. Perkins, E. Winchester, J. Spencer, et al. (1998)
Science 280, 1077-1082
 |  Abstract »  |  Full Text »

Oligonucleotide Ligation Assay for Detecting Mutations in the Human Immunodeficiency Virus Type 1 pol Gene That Are Associated with Resistance to Zidovudine, Didanosine, and Lamivudine.

R. E. Edelstein, D. A. Nickerson, V. O. Tobe, L. A. Manns-Arcuino, and L. M. Frenkel (1998)
J. Clin. Microbiol. 36, 569-572
 |  Abstract »  |  Full Text »

Molecular Diagnosis of Medium-Chain Acyl-CoA Dehydrogenase Deficiency by Oligonucleotide Ligation Assay.

M. Tuchman (1998)
Clin. Chem. 44, 10-11
 |  Full Text »  |  PDF »

Molecular diagnosis of medium-chain acyl-CoA dehydrogenase deficiency by oligonucleotide ligation assay.

E.-L. Romppanen, T. Mononen, and I. Mononen (1998)
Clin. Chem. 44, 68-71
 |  Abstract »  |  Full Text »  |  PDF »

Methods for detection of point mutations: performance and quality assessment.

P. Nollau and C. Wagener (1997)
Clin. Chem. 43, 1114-1128
 |  Abstract »  |  Full Text »  |  PDF »

Simple triple-label detection of seven cystic fibrosis mutations by time-resolved fluorometry.

P. Heinonen, A. Iitia, T. Torresani, and T. Lovgren (1997)
Clin. Chem. 43, 1142-1150
 |  Abstract »  |  Full Text »  |  PDF »

A simplified procedure for developing multiplex PCRs..

A P Shuber, V J Grondin, and K W Klinger (1995)
Genome Res. 5, 488-493
 |  Abstract »  |  PDF »

A one-step coupled amplification and oligonucleotide ligation procedure for multiplex genetic typing..

F A Eggerding (1995)
Genome Res. 4, 337-345
 |  Abstract »  |  PDF »

Detection of HCV RNA by the asymmetric gap ligase chain reaction..

R L Marshall, T G Laffler, M B Cerney, J C Sustachek, J D Kratochvil, and R L Morgan (1994)
Genome Res. 4, 80-84
 |  Abstract »  |  PDF »

Padlock probes: circularizing oligonucleotides for localized DNA detection.

M Nilsson, H Malmgren, M Samiotaki, M Kwiatkowski, B. Chowdhary, and U Landegren (1994)
Science 265, 2085-2088
 |  Abstract »  |  PDF »

Ligase chain reaction (LCR)--overview and applications..

M Wiedmann, W J Wilson, J Czajka, J Luo, F Barany, and C A Batt (1994)
Genome Res. 3, S51-S64
 |  PDF »

Molecular Diagnosis of Familial Adenomatous Polyposis.

S. M. Powell, G. M. Petersen, A. J. Krush, S. Booker, J. Jen, F. M. Giardiello, S. R. Hamilton, B. Vogelstein, and K. W. Kinzler (1993)
N. Engl. J. Med. 329, 1982-1987
 |  Abstract »  |  Full Text »

Clues to the pathogenesis of familial colorectal cancer.

L. Aaltonen, P Peltomaki, F. Leach, P Sistonen, L Pylkkanen, J. Mecklin, H Jarvinen, S. Powell, J Jen, Hamilton SR, et al. (1993)
Science 260, 812-816
 |  Abstract »  |  PDF »

Ligation-mediated PCR of restriction fragments from large DNA molecules..

D R Smith (1992)
Genome Res. 2, 21-27
 |  Abstract »  |  PDF »

PCR-based HLA class II typing..

U Gyllensten and M Allen (1991)
Genome Res. 1, 91-98
 |  PDF »

Capture PCR: efficient amplification of DNA fragments adjacent to a known sequence in human and YAC DNA..

M Lagerstrom, J Parik, H Malmgren, J Stewart, U Pettersson, and U Landegren (1991)
Genome Res. 1, 111-119
 |  Abstract »  |  PDF »

The ligase chain reaction in a PCR world..

F Barany (1991)
Genome Res. 1, 5-16
 |  PDF »

Autoimmune Disease and T-cell Immunologic Recognition.

L. Hood, V. Kumar, G. Osman, S.S. Beall, C. Gomez, W. Funkhouser, D.H. Kono, D. Nickerson, D.M. Zaller, and J.L. Urban (1989)
Cold Spring Harb Symp Quant Biol 54, 859-874
 |  Abstract »  |  PDF »

DNA diagnostics--molecular techniques and automation.

U Landegren, R Kaiser, C. Caskey, and L Hood (1988)
Science 242, 229-237
 |  Abstract »  |  PDF »

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