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Science 26 August 1988:
Vol. 241. no. 4869, pp. 1096 - 1098
DOI: 10.1126/science.241.4869.1096
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Articles

A Novel Target for Antidiuretic Hormone in Insects

JEFFREY H. SPRING 1, ANNE M. MORGAN 1, and SHELIA R. HAZELTON 1

1 Department of Biology, University of Southwestern Louisiana, Lafayette, LA 70504.

Diuresis in insects is controlled by two antagonistic hormone groups: diuretic hormones, which promote water loss, and antidiuretic hormones, which inhibit it. All known antidiuretic factors act solely to promote fluid reabsorption by the hindgut and do not affect secretion by the Malpighian tubules. In the house cricket, Acheta domesticus, an antidiuretic hormone was found that inhibits fluid secretion by the Malpighian tubules but has no effect on the hindgut. Correlations were found between the density of neurosecretory granules and the presence of antidiuretic hormone in the corpora cardiaca, suggesting that the hormone is released from specific axons. Its release is triggered by dehydration; the hormone is detectable in the hemolymph of water-deprived crickets. These results imply that an unusual mechanism regulates water balance in these insects.

Submitted on April 1, 1988
Accepted on June 23, 1988


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Isolation, Cloning, and Expression Mapping of a Gene Encoding an Antidiuretic Hormone and Other CAPA-Related Peptides in the Disease Vector, Rhodnius prolixus.
J.-P. Paluzzi, W. K. Russell, R. J. Nachman, and I. Orchard (2008)
Endocrinology 149, 4638-4646
   Abstract »    Full Text »    PDF »
An antidiuretic peptide (Tenmo-ADFb) with kinin-like diuretic activity on Malpighian tubules of the house cricket, Acheta domesticus (L.).
G. M. Coast, R. J. Nachman, and D. A. Schooley (2007)
J. Exp. Biol. 210, 3979-3989
   Abstract »    Full Text »    PDF »
Modulation of tyramine signaling by osmolality in an insect secretory epithelium.
E. M. Blumenthal (2005)
Am J Physiol Cell Physiol 289, C1261-C1267
   Abstract »    Full Text »    PDF »
The mechanism of action of the antidiuretic peptide Tenmo ADFa in Malpighian tubules of Aedes aegypti.
R. C. Massaro, L. W. Lee, A. B. Patel, D. S. Wu, M.-J. Yu, B. N. Scott, D. A. Schooley, K. M. Schegg, and K. W. Beyenbach (2004)
J. Exp. Biol. 207, 2877-2888
   Abstract »    Full Text »    PDF »
Antagonistic control of fluid secretion by the Malpighian tubules of Tenebrio molitor: effects of diuretic and antidiuretic peptides and their second messengers.
U. I. M. Wiehart, S. W. Nicolson, R. A. Eigenheer, and D. A. Schooley (2002)
J. Exp. Biol. 205, 493-501
   Abstract »    Full Text »    PDF »
Identification of a potent antidiuretic factor acting on beetle Malpighian tubules.
R. A. Eigenheer, S. W. Nicolson, K. M. Schegg, J. J. Hull, and D. A. Schooley (2002)
PNAS 99, 84-89
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)