Science 23 September 1988: Vol. 241. no. 4873, pp. 1632 - 1639 DOI: 10.1126/science.2971269

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Articles

Stem cell concepts renew cancer research.

J. E. Dick (2008)
Blood 112, 4793-4807
 |  Abstract »  |  Full Text »  |  PDF »

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases.

I. L. Weissman and J. A. Shizuru (2008)
Blood 112, 3543-3553
 |  Abstract »  |  Full Text »  |  PDF »

Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines.

C. I. Yu, M. Gallegos, F. Marches, G. Zurawski, O. Ramilo, A. Garcia-Sastre, J. Banchereau, and A. K. Palucka (2008)
Blood 112, 3671-3678
 |  Abstract »  |  Full Text »  |  PDF »

FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-{gamma}C-/- mice in vivo.

Q. Jiang, L. Zhang, R. Wang, J. Jeffrey, M. L. Washburn, D. Brouwer, S. Barbour, G. I. Kovalev, D. Unutmaz, and L. Su (2008)
Blood 112, 2858-2868
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Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.

N. Tonomura, K. Habiro, A. Shimizu, M. Sykes, and Y.-G. Yang (2008)
Blood 111, 4293-4296
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A Severe Combined Immunodeficient-hu In vivo Mouse Model of Human Primary Mantle Cell Lymphoma.

M. Wang, L. Zhang, X. Han, J. Yang, J. Qian, S. Hong, P. Lin, Y. Shi, J. Romaguera, L. W. Kwak, et al. (2008)
Clin. Cancer Res. 14, 2154-2160
 |  Abstract »  |  Full Text »  |  PDF »

Neutralizing B-Cell Activating Factor Antibody Improves Survival and Inhibits Osteoclastogenesis in a Severe Combined Immunodeficient Human Multiple Myeloma Model.

P. Neri, S. Kumar, M. T. Fulciniti, S. Vallet, S. Chhetri, S. Mukherjee, Y. Tai, D. Chauhan, P. Tassone, S. Venuta, et al. (2007)
Clin. Cancer Res. 13, 5903-5909
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Bearing a Disrupted Central DNA Flap Is Pathogenic In Vivo.

M. D. Marsden and J. A. Zack (2007)
J. Virol. 81, 6146-6150
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Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.

Z. Sun, P. W. Denton, J. D. Estes, F. A. Othieno, B. L. Wei, A. K. Wege, M. W. Melkus, A. Padgett-Thomas, M. Zupancic, A. T. Haase, et al. (2007)
J. Exp. Med. 204, 705-714
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Use of a Novel Chimeric Mouse Model with a Functionally Active Human Immune System To Study Human Immunodeficiency Virus Type 1 Infection.

D. S. An, B. Poon, R. H. T. Fang, K. Weijer, B. Blom, H. Spits, I. S. Y. Chen, and C. H. Uittenbogaart (2007)
Clin. Vaccine Immunol. 14, 391-396
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 infection and pathogenesis in a novel humanized mouse model.

L. Zhang, G. I. Kovalev, and L. Su (2007)
Blood 109, 2978-2981
 |  Abstract »  |  Full Text »  |  PDF »

Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination.

T. Shinohara, M. Kato, M. Takehashi, J. Lee, S. Chuma, N. Nakatsuji, M. Kanatsu-Shinohara, and M. Hirabayashi (2006)
PNAS 103, 13624-13628
 |  Abstract »  |  Full Text »  |  PDF »

Ex Vivo Expansion Does Not Alter the Capacity of Umbilical Cord Blood CD34+ Cells to Generate Functional T Lymphocytes and Dendritic Cells.

L. Kobari, M. C. Giarratana, J. C. Gluckman, L. Douay, and M. Rosenzwajg (2006)
Stem Cells 24, 2150-2157
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: T lineage differentiation from human embryonic stem cells.

Z. Galic, S. G. Kitchen, A. Kacena, A. Subramanian, B. Burke, R. Cortado, and J. A. Zack (2006)
PNAS 103, 11742-11747
 |  Abstract »  |  Full Text »  |  PDF »

Boosting functional hematolymphopoiesis in humanized mice.

T. Cheng (2006)
Blood 108, 411-412
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Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation.

P. Lan, N. Tonomura, A. Shimizu, S. Wang, and Y.-G. Yang (2006)
Blood 108, 487-492
 |  Abstract »  |  Full Text »  |  PDF »

Intramyocardial delivery of human CD133+ cells in a SCID mouse cryoinjury model: Bone marrow vs. cord blood-derived cells.

N. Ma, Y. Ladilov, J. M. Moebius, L. Ong, C. Piechaczek, A. David, A. Kaminski, Y.-H. Choi, W. Li, D. Egger, et al. (2006)
Cardiovasc Res 71, 158-169
 |  Abstract »  |  Full Text »  |  PDF »

Experimental Models to Study Development and Function of the Human Immune System In Vivo.

N. Legrand, K. Weijer, and H. Spits (2006)
J. Immunol. 176, 2053-2058
 |  Abstract »  |  Full Text »  |  PDF »

Human Interleukin-15 Improves Engraftment of Human T Cells in NOD-SCID Mice.

A. Sun, H. Wei, R. Sun, W. Xiao, Y. Yang, and Z. Tian (2006)
Clin. Vaccine Immunol. 13, 227-234
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Expression of Human Immunodeficiency Virus following Activation of Latently Infected Cells.

P. A. Arlen, D. G. Brooks, L. Y. Gao, D. Vatakis, H. J. Brown, and J. A. Zack (2006)
J. Virol. 80, 1599-1603
 |  Abstract »  |  Full Text »  |  PDF »

Stem Cell Research: Paths to Cancer Therapies and Regenerative Medicine.

I. Weissman (2005)
JAMA 294, 1359-1366
 |  Abstract »  |  Full Text »  |  PDF »

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chainnull mice.

F. Ishikawa, M. Yasukawa, B. Lyons, S. Yoshida, T. Miyamoto, G. Yoshimoto, T. Watanabe, K. Akashi, L. D. Shultz, and M. Harada (2005)
Blood 106, 1565-1573
 |  Abstract »  |  Full Text »  |  PDF »

A SCID-hu in vivo model of human Waldenstrom macroglobulinemia.

P. Tassone, P. Neri, J. L. Kutok, O. Tournilhac, D. D. Santos, E. Hatjiharissi, V. Munshi, S. Venuta, K. C. Anderson, S. P. Treon, et al. (2005)
Blood 106, 1341-1345
 |  Abstract »  |  Full Text »  |  PDF »

A clinically relevant SCID-hu in vivo model of human multiple myeloma.

P. Tassone, P. Neri, D. R. Carrasco, R. Burger, V. S. Goldmacher, R. Fram, V. Munshi, M. A. Shammas, L. Catley, G. S. Jacob, et al. (2005)
Blood 106, 713-716
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Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice.

R. Matsuura-Sawada, T. Murakami, Y. Ozawa, H. Nabeshima, J.-i. Akahira, Y. Sato, Y. Koyanagi, M. Ito, Y. Terada, and K. Okamura (2005)
Hum. Reprod. 20, 1477-1484
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Pertussis toxin B-oligomer inhibits HIV infection and replication in hu-PBL-SCID mice.

C. Lapenta, M. Spada, S. M. Santini, S. Racca, F. Dorigatti, G. Poli, F. Belardelli, and M. Alfano (2005)
Int. Immunol. 17, 469-475
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Human Cytomegalovirus Genes in the 15-Kilobase Region Are Required for Viral Replication in Implanted Human Tissues in SCID Mice.

W. Wang, S. L. Taylor, S. A. Leisenfelder, R. Morton, J. F. Moffat, S. Smirnov, and H. Zhu (2005)
J. Virol. 79, 2115-2123
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Anti-human CTLA-4 monoclonal antibody promotes T-cell expansion and immunity in a hu-PBL-SCID model: a new method for preclinical screening of costimulatory monoclonal antibodies.

K. F. May Jr, S. Roychowdhury, D. Bhatt, E. Kocak, X.-F. Bai, J.-Q. Liu, A. K. Ferketich, E. W. Martin Jr, M. A. Caligiuri, P. Zheng, et al. (2005)
Blood 105, 1114-1120
 |  Abstract »  |  Full Text »  |  PDF »

R5 Human Immunodeficiency Virus Type 1 Infection of Fetal Thymic Organ Culture Induces Cytokine and CCR5 Expression.

S. K. Choudhary, N. R. Choudhary, K. C. Kimbrell, J. Colasanti, A. Ziogas, D. Kwa, H. Schuitemaker, and D. Camerini (2005)
J. Virol. 79, 458-471
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Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells.

P. Tassone, V. S. Goldmacher, P. Neri, A. Gozzini, M. A. Shammas, K. R. Whiteman, L. L. Hylander-Gans, D. R. Carrasco, T. Hideshima, R. Shringarpure, et al. (2004)
Blood 104, 3688-3696
 |  Abstract »  |  Full Text »  |  PDF »

Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow.

L. Xia, J. M. McDaniel, T. Yago, A. Doeden, and R. P. McEver (2004)
Blood 104, 3091-3096
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Targeting c-Mpl for Revival of Human Immunodeficiency Virus Type 1-Induced Hematopoietic Inhibition When CD34+ Progenitor Cells Are Re-Engrafted into a Fresh Stromal Microenvironment In Vivo.

P. S. Koka, C. M. R. Kitchen, and S. T. Reddy (2004)
J. Virol. 78, 11385-11392
 |  Abstract »  |  Full Text »  |  PDF »

Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism.

P. Lan, L. Wang, B. Diouf, H. Eguchi, H. Su, R. Bronson, D. H. Sachs, M. Sykes, and Y.-G. Yang (2004)
Blood 103, 3964-3969
 |  Abstract »  |  Full Text »  |  PDF »

Development of a Human Adaptive Immune System in Cord Blood Cell-Transplanted Mice.

E. Traggiai, L. Chicha, L. Mazzucchelli, L. Bronz, J.-C. Piffaretti, A. Lanzavecchia, and M. G. Manz (2004)
Science 304, 104-107
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Cotransplantation of third-party mesenchymal stromal cells can alleviate single-donor predominance and increase engraftment from double cord transplantation.

D.-W. Kim, Y.-J. Chung, T.-G. Kim, Y.-L. Kim, and I.-H. Oh (2004)
Blood 103, 1941-1948
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Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body.

N. Kambe, H. Hiramatsu, M. Shimonaka, H. Fujino, R. Nishikomori, T. Heike, M. Ito, K. Kobayashi, Y. Ueyama, N. Matsuyoshi, et al. (2004)
Blood 103, 860-867
 |  Abstract »  |  Full Text »  |  PDF »

Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors.

A. K. Palucka, J. Gatlin, J. P. Blanck, M. W. Melkus, S. Clayton, H. Ueno, E. T. Kraus, P. Cravens, L. Bennett, A. Padgett-Thomas, et al. (2003)
Blood 102, 3302-3310
 |  Abstract »  |  Full Text »  |  PDF »

Identification of T cell-signaling pathways that stimulate latent HIV in primary cells.

D. G. Brooks, P. A. Arlen, L. Gao, C. M. R. Kitchen, and J. A. Zack (2003)
PNAS 100, 12955-12960
 |  Abstract »  |  Full Text »  |  PDF »

Alloimmune Injury and Rejection of Human Skin Grafts on Human Peripheral Blood Lymphocyte-Reconstituted Non-Obese Diabetic Severe Combined Immunodeficient {beta}2-Microglobulin-Null Mice.

N. A. Turgeon, S. J. Banuelos, L. D. Shultz, B. L. Lyons, N. Iwakoshi, D. L. Greiner, J. P. Mordes, A. A. Rossini, and M. C. Appel (2003)
Experimental Biology and Medicine 228, 1096-1104
 |  Abstract »  |  Full Text »  |  PDF »

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/{gamma}cnull mice model.

H. Hiramatsu, R. Nishikomori, T. Heike, M. Ito, K. Kobayashi, K. Katamura, and T. Nakahata (2003)
Blood 102, 873-880
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Effects of IL-7 on Early Human Thymocyte Progenitor Cells In Vitro and in SCID-hu Thy/Liv Mice.

L. A. Napolitano, C. A. Stoddart, M. B. Hanley, E. Wieder, and J. M. McCune (2003)
J. Immunol. 171, 645-654
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T Cells of Atopic Asthmatics Preferentially Infiltrate Into Human Bronchial Xenografts in SCID Mice.

K. Tsumori, H. Kohrogi, E. Goto, N. Hirata, S. Hirosako, K. Fujii, M. Ando, O. Kawano, and H. Mizuta (2003)
J. Immunol. 170, 5712-5718
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Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/{gamma}cnull Mice: Suppression by an Inhibitor against NF-{kappa}B.

M. Z. Dewan, K. Terashima, M. Taruishi, H. Hasegawa, M. Ito, Y. Tanaka, N. Mori, T. Sata, Y. Koyanagi, M. Maeda, et al. (2003)
J. Virol. 77, 5286-5294
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The NOD/SCID chimeric mouse model of human B cell development: studies on the VH4 family immunoglobulin repertoire and implications for SLE.

G R Kolar and J D Capra (2003)
Lupus 12, 158-162
 |  Abstract »  |  PDF »

The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development.

R. Schotte, M.-C. Rissoan, N. Bendriss-Vermare, J.-M. Bridon, T. Duhen, K. Weijer, F. Briere, and H. Spits (2003)
Blood 101, 1015-1023
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Tat-mediated Transactivation and HIV-1 Replication by Human Anti-hCyclinT1 Intrabodies.

J. Bai, J. Sui, R. Y. Zhu, A. St. C. Tallarico, F. Gennari, D. Zhang, and W. A. Marasco (2003)
J. Biol. Chem. 278, 1433-1442
 |  Abstract »  |  Full Text »  |  PDF »

TCR{gamma}{delta}+ and CD161+ Thymocytes Express HIV-1 in the SCID-hu Mouse, Potentially Contributing to Immune Dysfunction in HIV Infection.

K. B. Gurney, O. O. Yang, S. B. Wilson, and C. H. Uittenbogaart (2002)
J. Immunol. 169, 5338-5346
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NOD/SCID/gamma cnull mouse: an excellent recipient mouse model for engraftment of human cells.

M. Ito, H. Hiramatsu, K. Kobayashi, K. Suzue, M. Kawahata, K. Hioki, Y. Ueyama, Y. Koyanagi, K. Sugamura, K. Tsuji, et al. (2002)
Blood 100, 3175-3182
 |  Abstract »  |  Full Text »  |  PDF »

The in vivo development of human T cells from CD34+ cells in the murine thymic environment.

Y. Saito, Y. Kametani, K. Hozumi, N. Mochida, K. Ando, M. Ito, T. Nomura, Y. Tokuda, H. Makuuchi, T. Tajima, et al. (2002)
Int. Immunol. 14, 1113-1124
 |  Abstract »  |  Full Text »  |  PDF »

Generation of CD3+CD8low Thymocytes in the HIV Type 1-Infected Thymus.

M. E. Keir, M. G. Rosenberg, J. K. Sandberg, K. A. Jordan, A. Wiznia, D. F. Nixon, C. A. Stoddart, and J. M. McCune (2002)
J. Immunol. 169, 2788-2796
 |  Abstract »  |  Full Text »  |  PDF »

Functional Human T Lymphocyte Development from Cord Blood CD34+ Cells in Nonobese Diabetic/Shi-scid, IL-2 Receptor {gamma} Null Mice.

T. Yahata, K. Ando, Y. Nakamura, Y. Ueyama, K. Shimamura, N. Tamaoki, S. Kato, and T. Hotta (2002)
J. Immunol. 169, 204-209
 |  Abstract »  |  Full Text »  |  PDF »

Telomeres, X-Inactivation Ratios, and Hematopoietic Stem Cell Transplantation in Humans: A Review.

I. Thornley and M. H. Freedman (2002)
Stem Cells 20, 198-204
 |  Abstract »  |  Full Text »  |  PDF »

Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo.

K. Weijer, C. H. Uittenbogaart, A. Voordouw, F. Couwenberg, J. Seppen, B. Blom, F. A. Vyth-Dreese, and H. Spits (2002)
Blood 99, 2752-2759
 |  Abstract »  |  Full Text »  |  PDF »

Effects of exogenous interleukin-7 on human thymus function.

Y. Okamoto, D. C. Douek, R. D. McFarland, and R. A. Koup (2002)
Blood 99, 2851-2858
 |  Abstract »  |  Full Text »  |  PDF »

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34+ cells.

T. C. C. Kerre, G. De Smet, M. De Smedt, A. Zippelius, M. J. Pittet, A. W. Langerak, J. De Bosscher, F. Offner, B. Vandekerckhove, and J. Plum (2002)
Blood 99, 1620-1626
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{alpha} Secretion by Type 2 Predendritic Cells Up-Regulates MHC Class I in the HIV-1-Infected Thymus.

M. E. Keir, C. A. Stoddart, V. Linquist-Stepps, M. E. Moreno, and J. M. McCune (2002)
J. Immunol. 168, 325-331
 |  Abstract »  |  Full Text »  |  PDF »

Inflammation, Immune Reactivity, and Angiogenesis in a Severe Combined Immunodeficiency Model of Rheumatoid Arthritis.

L. S. Davis, M. Sackler, R. I. Brezinschek, E. Lightfoot, J. L. Bailey, N. Oppenheimer-Marks, and P. E. Lipsky (2002)
Am. J. Pathol. 160, 357-367
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a candidate human neurohematopoietic stem-cell population.

C.-C. Shih, Y. Weng, A. Mamelak, T. LeBon, M. C.-T. Hu, and S. J. Forman (2001)
Blood 98, 2412-2422
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1 IIIB Selected for Replication In Vivo Exhibits Increased Envelope Glycoproteins in Virions without Alteration in Coreceptor Usage: Separation of In Vivo Replication from Macrophage Tropism.

E. D. Miller, K. M. Duus, M. Townsend, Y. Yi, R. Collman, M. Reitz, and L. Su (2001)
J. Virol. 75, 8498-8506
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Function of Chemokine Receptors on Human Thymocytes: Implications for Infection by Human Immunodeficiency Virus Type 1.

J. R. Taylor Jr., K. C. Kimbrell, R. Scoggins, M. Delaney, L. Wu, and D. Camerini (2001)
J. Virol. 75, 8752-8760
 |  Abstract »  |  Full Text »  |  PDF »

Cytopathicity of Human Immunodeficiency Virus Type 1 Primary Isolates Depends on Coreceptor Usage and Not Patient Disease Status.

J. F. Kreisberg, D. Kwa, B. Schramm, V. Trautner, R. Connor, H. Schuitemaker, J. I. Mullins, A. B. van't Wout, and M. A. Goldsmith (2001)
J. Virol. 75, 8842-8847
 |  Abstract »  |  Full Text »  |  PDF »

Rapid and efficient homing of human CD34+CD38{-}/lowCXCR4+ stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2mnull mice.

O. Kollet, A. Spiegel, A. Peled, I. Petit, T. Byk, R. Hershkoviz, E. Guetta, G. Barkai, A. Nagler, and T. Lapidot (2001)
Blood 97, 3283-3291
 |  Abstract »  |  Full Text »  |  PDF »

Primate Spermatogonial Stem Cells Colonize Mouse Testes.

M. Nagano, J. R. McCarrey, and R. L. Brinster (2001)
Biol Reprod 64, 1409-1416
 |  Abstract »  |  Full Text »

Separation of Human Immunodeficiency Virus Type 1 Replication from nef-Mediated Pathogenesis in the Human Thymus.

K. M. Duus, E. D. Miller, J. A. Smith, G. I. Kovalev, and L. Su (2001)
J. Virol. 75, 3916-3924
 |  Abstract »  |  Full Text »

Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production.

L. E. Perez, H. M. Rinder, C. Wang, J. B. Tracey, N. Maun, and D. S. Krause (2001)
Blood 97, 1635-1643
 |  Abstract »  |  Full Text »  |  PDF »

Transplantation Tolerance and Autoimmunity After Xenogeneic Thymus Transplantation.

G. Xia, J. Goebels, O. Rutgeerts, M. Vandeputte, and M. Waer (2001)
J. Immunol. 166, 1843-1854
 |  Abstract »  |  Full Text »  |  PDF »

T Lymphocytes Promote the Development of Bone Marrow-Derived APC in the Central Nervous System.

S. Subramanian, D. N. Bourdette, C. Corless, A. A. Vandenbark, H. Offner, and R. E. Jones (2001)
J. Immunol. 166, 370-376
 |  Abstract »  |  Full Text »  |  PDF »

Immune Privilege and Immunogenicity Reside among Different Layers of the Mouse Cornea.

J. Hori, N. C. Joyce, and J. W. Streilein (2000)
Invest. Ophthalmol. Vis. Sci. 41, 3032-3042
 |  Abstract »  |  Full Text »

Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice.

J. Barquinero, J. C. Segovia, M. Ramirez, A. Limon, G. Guenechea, T. Puig, J. Briones, J. Garcia, and J. A. Bueren (2000)
Blood 95, 3085-3093
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1 Pathogenesis in SCID-hu Mice Correlates with Syncytium-Inducing Phenotype and Viral Replication.

D. Camerini, H.-P. Su, G. Gamez-Torre, M. L. Johnson, J. A. Zack, and I. S. Y. Chen (2000)
J. Virol. 74, 3196-3204
 |  Abstract »  |  Full Text »

Pathogenesis of Primary R5 Human Immunodeficiency Virus Type 1 Clones in SCID-hu Mice.

R. M. Scoggins, J. R. Taylor Jr., J. Patrie, A. B. van't Wout, H. Schuitemaker, and D. Camerini (2000)
J. Virol. 74, 3205-3216
 |  Abstract »  |  Full Text »

Functional Reconstitution of Thymopoiesis after Human Immunodeficiency Virus Infection.

S. G. Kitchen, S. Killian, J. V. Giorgi, and J. A. Zack (2000)
J. Virol. 74, 2943-2948
 |  Abstract »  |  Full Text »

Antiviral Activity of 2'-Deoxy-3'-Oxa-4'-Thiocytidine (BCH-10652) against Lamivudine-Resistant Human Immunodeficiency Virus Type 1 in SCID-hu Thy/Liv Mice.

C. A. Stoddart, M. E. Moreno, V. D. Linquist-Stepps, C. Bare, M. R. Bogan, A. Gobbi, R. W. Buckheit Jr., J. Bedard, R. F. Rando, and J. M. McCune (2000)
Antimicrob. Agents Chemother. 44, 783-786
 |  Abstract »  |  Full Text »

NOD/LtSz-Rag1null Mice: An Immunodeficient and Radioresistant Model for Engraftment of Human Hematolymphoid Cells, HIV Infection, and Adoptive Transfer of NOD Mouse Diabetogenic T Cells.

L. D. Shultz, P. A. Lang, S. W. Christianson, B. Gott, B. Lyons, S. Umeda, E. Leiter, R. Hesselton, E. J. Wagar, J. H. Leif, et al. (2000)
J. Immunol. 164, 2496-2507
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice.

B. Schiedlmeier, K. Kuhlcke, H. G. Eckert, C. Baum, W. J. Zeller, and S. Fruehauf (2000)
Blood 95, 1237-1248
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Epithelium-Deficient Corneal Allografts Display Immune Privilege beneath the Kidney Capsule.

J. Hori, N. Joyce, and J. W. Streilein (2000)
Invest. Ophthalmol. Vis. Sci. 41, 443-452
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Marking and Gene Expression by a Lentivirus Vector in Transplanted Human and Nonhuman Primate CD34+ Cells.

D. S. An, R. P. Wersto, B. A. Agricola, M. E. Metzger, S. Lu, R. G. Amado, I. S. Y. Chen, and R. E. Donahue (2000)
J. Virol. 74, 1286-1295
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Epithelial stem cell-mediated development of the human respiratory mucosa in SCID mice.

A Delplanque, C Coraux, R Tirouvanziam, I Khazaal, E Puchelle, P Ambros, D Gaillard, and B Peault (2000)
J. Cell Sci. 113, 767-778
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Experimental Transmission of Kaposi's Sarcoma-associated Herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv Mice.

D. Dittmer, C. Stoddart, R. Renne, V. Linquist-Stepps, M.E. Moreno, C. Bare, J.M. McCune, and D. Ganem (1999)
J. Exp. Med. 190, 1857-1868
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Thymic Repopulation by CD34+ Human Cord Blood Cells After Expansion in Stroma-Free Culture.

B. Verhasselt, T. Kerre, E. Naessens, D. Vanhecke, M. De Smedt, B. Vandekerckhove, and J. Plum (1999)
Blood 94, 3644-3652
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Human Cord Blood Progenitors Sustain Thymic T-Cell Development and a Novel Form of Angiogenesis.

L. Crisa, V. Cirulli, K. A. Smith, M. H. Ellisman, B. E. Torbett, and D. R. Salomon (1999)
Blood 94, 3928-3940
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The Proliferative Potential of Myeloma Plasma Cells Manifest in the SCID-hu Host.

S. Yaccoby and J. Epstein (1999)
Blood 94, 3576-3582
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Human Immunodeficiency Virus Type 1-Induced Hematopoietic Inhibition Is Independent of Productive Infection of Progenitor Cells In Vivo.

P. S. Koka, B. D. Jamieson, D. G. Brooks, and J. A. Zack (1999)
J. Virol. 73, 9089-9097
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Homing of Human Cells in the Fetal Sheep Model: Modulation by Antibodies Activating or Inhibiting Very Late Activation Antigen-4-Dependent Function.

E. D. Zanjani, A. W. Flake, G. Almeida-Porada, N. Tran, and T. Papayannopoulou (1999)
Blood 94, 2515-2522
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R5 Strains of Human Immunodeficiency Virus Type 1 from Rapid Progressors Lacking X4 Strains Do Not Possess X4-Type Pathogenicity in Human Thymus.

R. D. Berkowitz, A. B. van 't Wout, N. A. Kootstra, M. E. Moreno, V. D. Linquist-Stepps, C. Bare, C. A. Stoddart, H. Schuitemaker, and J. M. McCune (1999)
J. Virol. 73, 7817-7822
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Human Hematopoietic Stem/Progenitor Cells Generate CD5+ B Lymphoid Cells in NOD/SCID Mice.

E. M. Novelli, M. Ramírez, W. Leung, and C. I. Civin (1999)
Stem Cells 17, 242-252
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