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Science 23 September 1988:
Vol. 241. no. 4873, pp. 1645 - 1649
DOI: 10.1126/science.3420416
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Articles

Science, Vol 241, Issue 4873, 1645-1649
Copyright © 1988 by American Association for the Advancement of Science

articles

Accelerated electron transfer between metal complexes mediated by DNA

MD Purugganan, CV Kumar, NJ Turro, and JK Barton

Department of Chemistry, Columbia University, New York, NY 10027.

DNA-mediated long-range electron transfer from photoexcited 1,10-phenanthroline complexes of ruthenium, Ru(phen)2(3)+, to isostructural complexes of cobalt(III), rhodium(III), and chromium(III) bound along the helical strand. The efficiency of transfer depended upon binding mode and driving force. For a given donor-acceptor pair, surface-bound complexes showed greater rate enhancements than those that were intercalatively bound. Even in rigid glycerol at 253 K, the rates for donor-acceptor pairs bound to DNA remained enhanced. For the series of acceptors, the greatest enhancement in electron-transfer rate was found with chromium, the acceptor of intermediate driving force. The DNA polymer appears to provide an efficient intervening medium to couple donor and acceptor metal complexes for electron transfer.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Long-range photoinduced electron transfer through a DNA helix.
C. Murphy, M. Arkin, Y Jenkins, N. Ghatlia, S. Bossmann, N. Turro, and J. Barton (1993)
Science 262, 1025-1029
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