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Science 14 October 1988:
Vol. 242. no. 4876, pp. 229 - 237
DOI: 10.1126/science.3051381
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Articles
Science, Vol 242, Issue 4876, 229-237
Copyright © 1988 by American Association for the Advancement of Science
DNA diagnostics--molecular techniques and automation
U Landegren,
R Kaiser,
CT Caskey,
and
L Hood
Division of Biology, California Institute of Technology, Pasadena 91125.
Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.
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