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Science 11 November 1988:
Vol. 242. no. 4880, pp. 916 - 919
DOI: 10.1126/science.3187532
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Articles

Science, Vol 242, Issue 4880, 916-919
Copyright © 1988 by American Association for the Advancement of Science

articles

A larger spectrum of severe HIV-1--related disease in intravenous drug users in New York City

RL Stoneburner, DC Des Jarlais, D Benezra, L Gorelkin, JL Sotheran, Friedman SR, S Schultz, M Marmor, D Mildvan, and R Maslansky

AIDS Research Unit, New York City Department of Health, NY 10013.

Increasing mortality in intravenous (IV) drug users not reported to surveillance as acquired immunodeficiency syndrome (AIDS) has occurred in New York City coincident with the AIDS epidemic. From 1981 to 1986, narcotics-related deaths increased on average 32% per year from 492 in 1981 to 1996 in 1986. This increase included deaths from AIDS increasing from 0 to 905 and deaths from other causes, many of which were infectious diseases, increasing from 492 to 1091. Investigations of these deaths suggest a causal association with human immunodeficiency virus (HIV) infection. These deaths may represent a spectrum of HIV-related disease that has not been identified through AIDS surveillance and has resulted in a large underestimation of the impact of AIDS on IV drug users and blacks and Hispanics.


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