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Science 20 October 1989:
Vol. 246. no. 4928, pp. 352 - 358
DOI: 10.1126/science.2678474
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Articles

Science, Vol 246, Issue 4928, 352-358
Copyright © 1989 by American Association for the Advancement of Science

articles

Fish as model systems

DA Powers

Hopkins Marine Station, Stanford University, Pacific Grove, CA 93950

Fish represent the largest and most diverse group of vertebrates. Their evolutionary position relative to other vertebrates and their ability to adapt to a wide variety of environments make them ideal for studying both organismic and molecular evolution. A number of other characteristics make them excellent experimental models for studies in embryology, neurobiology, endocrinology, environmental biology, and other areas. In fact, they have played a critical role in the development of several of these disciplines. Research techniques that enable scientists to make isogenic lines in a single generation, create and maintain mutants, culture cells, and transfer cloned genes into embryos signal an increasing role for fish as experimental models.


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