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Science 3 November 1989: Vol. 246. no. 4930, pp. 614 - 621 DOI: 10.1126/science.2683077
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Articles
Science, Vol 246, Issue 4930, 614-621
Copyright © 1989 by American Association for the Advancement of Science
Dominoes and clocks: the union of two views of the cell cycle
AW Murray
and
MW Kirschner
Department of Physiology, School of Medicine, University of California, San Francisco 94143-0448.
We review the recent advances in understanding transitions within the cell cycle. These have come from both genetic and biochemical approaches. We discuss the phylogenetic conservation of the mechanisms that induce mitosis and their implications for other transitions in the cell cycle.
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