Science 8 December 1989: Vol. 246. no. 4935, pp. 1275 - 1281 DOI: 10.1126/science.2531466

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Articles

Combinatorial surrobody libraries.

L. Xu, H. Yee, C. Chan, A. K. Kashyap, L. Horowitz, M. Horowitz, R. R. Bhatt, and R. A. Lerner (2008)
PNAS 105, 10756-10761
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In vitro evolution of an antibody fragment population to find high-affinity hapten binders.

H. Persson, H. Wallmark, A. Ljungars, J. Hallborn, and M. Ohlin (2008)
Protein Eng. Des. Sel. 21, 485-493
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Phage escape libraries for checkmate analysis.

T. J. Dickerson, K. M. McKenzie, A. S. Hoyt, M. R. Wood, K. D. Janda, S. B. Brenner, and R. A. Lerner (2007)
PNAS 104, 12703-12708
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanisms of Improvement of Hydrolytic Antibody 6D9 by Site-Directed Mutagenesis.

N. Takahashi-Ando, K. Shimazaki, H. Kakinuma, I. Fujii, and Y. Nishi (2006)
J. Biochem. 140, 509-515
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A general method for greatly improving the affinity of antibodies by using combinatorial libraries.

A. Rajpal, N. Beyaz, L. Haber, G. Cappuccilli, H. Yee, R. R. Bhatt, T. Takeuchi, R. A. Lerner, and R. Crea (2005)
PNAS 102, 8466-8471
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Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope.

S. Quaratino, J. Ruf, M. Osman, J. Guo, S. McLachlan, B. Rapoport, and M. Londei (2005)
J. Immunol. 174, 557-563
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Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis.

B. Felding-Habermann, R. A. Lerner, A. Lillo, S. Zhuang, M. R. Weber, S. Arrues, C. Gao, S. Mao, A. Saven, and K. D. Janda (2004)
PNAS 101, 17210-17215
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{kappa} Editing Rescues Autoreactive B Cells Destined for Deletion in Mice Transgenic for a Dual Specific Anti-Laminin Ig.

G. F. Brady, K. L. Congdon, A. G. Clark, F. N. A. Sackey, E. H. Rudolph, M. Z. Radic, and M. H. Foster (2004)
J. Immunol. 172, 5313-5321
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Recombinant Single-Chain Variable Fragment Antibodies Directed against Clostridium difficile Toxin B Produced by Use of an Optimized Phage Display System.

X. K. Deng, L. A. Nesbit, and K. J. Morrow Jr. (2003)
Clin. Vaccine Immunol. 10, 587-595
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Production of a Functional Catalytic Antibody ScFv-NusA Fusion Protein in Bacterial Cytoplasm.

L. Zheng, U. Baumann, and J.-L. Reymond (2003)
J. Biochem. 133, 577-581
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Analysis of IgE Antibodies from a Patient with Atopic Dermatitis: Biased V Gene Usage and Evidence for Polyreactive IgE Heavy Chain Complementarity-Determining Region 3.

M. R. Edwards, W. Brouwer, C. H. Y. Choi, J. Ruhno, R. L. Ward, and A. M. Collins (2002)
J. Immunol. 168, 6305-6313
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Oligopeptides That Cross-react with Carbohydrate-specific Antibodies by Real Time Kinetics, In-solution Competition Enzyme-linked Immunosorbent Assay, and Immunological Analyses.

P. J. Brett, H. Tiwana, I. M. Feavers, and B. M. Charalambous (2002)
J. Biol. Chem. 277, 20468-20476
 |  Abstract »  |  Full Text »  |  PDF »

Human-Derived Anti-Oxidized LDL Autoantibody Blocks Uptake of Oxidized LDL by Macrophages and Localizes to Atherosclerotic Lesions In Vivo.

P. X. Shaw, S. Horkko, S. Tsimikas, M.-K. Chang, W. Palinski, G. J. Silverman, P. P. Chen, and J. L. Witztum (2001)
Arterioscler. Thromb. Vasc. Biol. 21, 1333-1339
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the Diversity of a Sheep Antibody Repertoire as Revealed from a Bacteriophage Display Library.

K. A. Charlton, S. Moyle, A. J. R. Porter, and W. J. Harris (2000)
J. Immunol. 164, 6221-6229
 |  Abstract »  |  Full Text »  |  PDF »

Human Anti-Thyroid Peroxidase Single-Chain Fragment Variable of Ig Isolated from a Combinatorial Library Assembled In-Cell: Insights into the In Vivo.

, , , , , , , , , and (2000)
J. Immunol. 164, 4162-4169
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Drug Discovery: A Historical Perspective.

J. Drews (2000)
Science 287, 1960-1964
 |  Abstract »  |  Full Text »

Identification of a human epitope in hepatitis C virus (HCV) core protein using a molecularly cloned antibody repertoire from a non-symptomatic, anti-HCV-positive patient.

V. Barban, S. Fraysse-Corgier, G. Paranhos-Baccala, M. Petit, C. Manin, Y. Berard, A. M. Prince, B. Mandrand, and P. Meulien (2000)
J. Gen. Virol. 81, 461-469
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Passive Immunization Against Dental Caries and Periodontal Disease: Development of Recombinant and Human Monoclonal Antibodies.

Y. Abiko (2000)
Critical Reviews in Oral Biology & Medicine 11, 140-158
 |  Abstract »  |  Full Text »  |  PDF »

Somatic Mutation and Light Chain Rearrangement Generate Autoimmunity in Anti–single-stranded DNA Transgenic MRL/lpr Mice.

F. Brard, M. Shannon, E. L. Prak, S. Litwin, and M. Weigert (1999)
J. Exp. Med. 190, 691-704
 |  Abstract »  |  Full Text »  |  PDF »

Bringing biological solutions to chemical problems.

P. G. Schultz (1998)
PNAS 95, 14590-14591
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Mapping the Prion Protein Using Recombinant Antibodies.

R. A. Williamson, D. Peretz, C. Pinilla, H. Ball, R. B. Bastidas, R. Rozenshteyn, R. A. Houghten, S. B. Prusiner, and D. R. Burton (1998)
J. Virol. 72, 9413-9418
 |  Abstract »  |  Full Text »  |  PDF »

A phage display approach for rapid antibody humanization: Designed combinatorial V gene libraries.

C. Rader, D. A. Cheresh, and C. F. Barbas III (1998)
PNAS 95, 8910-8915
 |  Abstract »  |  Full Text »  |  PDF »

Site-Directed C3a Receptor Antibodies from Phage Display Libraries.

H. Hawlisch, R. Frank, M. Hennecke, M. Baensch, B. Sohns, L. Arseniev, W. Bautsch, A. Kola, A. Klos, and J. Kohl (1998)
J. Immunol. 160, 2947-2958
 |  Abstract »  |  Full Text »  |  PDF »

Simian Immunodeficiency Virus (SIV) Envelope-Specific Fabs with High-Level Homologous Neutralizing Activity: Recovery from a Long-Term-Nonprogressor SIV-Infected Macaque.

J. Glamann, D. R. Burton, P. W. H. I. Parren, H. J. Ditzel, K. A. Kent, C. Arnold, D. Montefiori, and V. M. Hirsch (1998)
J. Virol. 72, 585-592
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Identification of Framework Residues in a Secreted Recombinant Antibody Fragment That Control Production Level and Localization in Escherichia coli.

G. Forsberg, M. Forsgren, M. Jaki, M. Norin, C. Sterky, A. Enhorning, K. Larsson, M. Ericsson, and P. Bjork (1997)
J. Biol. Chem. 272, 12430-12436
 |  Abstract »  |  Full Text »  |  PDF »

Purification of Storage Granule Protein-23. A NOVEL PROTEIN IDENTIFIED BY PHAGE DISPLAY TECHNOLOGY AND INTERACTION WITH TYPE I PLASMINOGEN ACTIVATOR INHIBITOR.

I. M. Lang, T. L. Chuang, C. F. Barbas III, and R. R. Schleef (1996)
J. Biol. Chem. 271, 30126-30135
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Metal Binding Properties of a Monoclonal Antibody Directed toward Metal-Chelate Complexes.

D. A. Blake, P. Chakrabarti, M. Khosraviani, F. M. Hatcher, C. M. Westhoff, P. Goebel, D. E. Wylie, and R. C. Blake II (1996)
J. Biol. Chem. 271, 27677-27685
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Crystal Structure of a Cross-reaction Complex between Fab F9.13.7 and Guinea Fowl Lysozyme.

J. Lescar, M. Pellegrini, H. Souchon, D. Tello, R. J. Poljak, N. Peterson, M. Greene, and P. M. Alzari (1995)
J. Biol. Chem. 270, 18067-18076
 |  Abstract »  |  Full Text »  |  PDF »

A Mouse Ig [IMAGE] Domain of Very Unusual Framework Structure Loses Function when Converted to the Consensus.

L. Ge, A. Lupas, S. Peraldi-Roux, S. Spada, and A. Plückthun (1995)
J. Biol. Chem. 270, 12446-12451
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Antibodies in Bioactive Peptide Design.

C. Monfardini, T. Kieber-Emmons, J. M. VonFeldt, B. O'Malley, H. Rosenbaum, A. P. Godillot, K. Kaushansky, C. B. Brown, D. Voet, D. E. McCallus, et al. (1995)
J. Biol. Chem. 270, 6628-6638
 |  Abstract »  |  Full Text »  |  PDF »

Construction of phagemid display libraries with PCR-amplified immunoglobulin sequences..

H H Hogrefe and B Shopes (1994)
Genome Res. 4, S109-S122
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Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.

Y. Zou, H Gu, and K Rajewsky (1993)
Science 262, 1271-1274
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Antibodies without immunization.

R. Lerner, A. Kang, J. Bain, D. Burton, and C. Barbas 3rd (1992)
Science 258, 1313-1314
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Direct PCR sequencing of murine immunoglobulin genes using E. coli single-stranded DNA-binding protein..

R Rapley, S Flora, and M R Walker (1992)
Genome Res. 2, 99-101
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Monoclonal antibodies in diagnosis and therapy.

T. Waldmann (1991)
Science 252, 1657-1662
 |  Abstract »  |  PDF »

At the crossroads of chemistry and immunology: catalytic antibodies.

R. Lerner, S. Benkovic, and P. Schultz (1991)
Science 252, 659-667
 |  Abstract »  |  PDF »

Monoclonal Antibodies: From the Research Lab to the Pharmacy.

D. Brixner (1991)
Journal of Pharmacy Practice 4, 94-102
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Metalloantibodies.

B. Iverson, S. Iverson, V. Roberts, E. Getzoff, J. Tainer, S. Benkovic, and R. Lerner (1990)
Science 249, 659-662
 |  Abstract »  |  PDF »

Data sharing: a declining ethic?.

E Marshall (1990)
Science 248, 952-957
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MONOCLONAL ANTIBODIES PRODUCED IN BACTERIA: FURTHER ADVANCE.

(1989)
Journal Watch (General) 1989, 6
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Molecular basis of lutropin recognition by the mannose/GalNAc-4-SO4 receptor.

D. S. Roseman and J. U. Baenziger (2000)
PNAS 97, 9949-9954
 |  Abstract »  |  Full Text »  |  PDF »

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