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Science 28 September 1990:
Vol. 249. no. 4976, pp. 1527 - 1533
DOI: 10.1126/science.2218494
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Articles

Science, Vol 249, Issue 4976, 1527-1533
Copyright © 1990 by American Association for the Advancement of Science

articles

New methods of drug delivery

R Langer

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139.

Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions. Recently, a number of novel drug delivery approaches have been developed. These approaches include drug modification by chemical means, drug entrapment in small vesicles that are injected into the bloodstream, and drug entrapment within pumps or polymeric materials that are placed in desired bodily compartments (for example, the eye or beneath the skin). These techniques have already led to delivery systems that improve human health, and continued research may revolutionize the way many drugs are delivered.


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