Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 5 October 1990:
Vol. 250. no. 4977, pp. 53 - 61
DOI: 10.1126/science.2218514
Prev | Table of Contents | Next

Articles

Science, Vol 250, Issue 4977, 53-61
Copyright © 1990 by American Association for the Advancement of Science

articles

Functional magnetic resonance imaging in medicine and physiology

CT Moonen, PC van Zijl, JA Frank, D Le Bihan, and ED Becker

National Institutes of Health, Bethesda, MD 20892.

Magnetic resonance imaging (MRI) is a well-established diagnostic tool that provides detailed information about macroscopic structure and anatomy. Recent advances in MRI allow the noninvasive spatial evaluation of various biophysical and biochemical processes in living systems. Specifically, the motion of water can be measured in processes such as vascular flow, capillary flow, diffusion, and exchange. In addition, the concentrations of various metabolites can be determined for the assessment of regional regulation of metabolism. Examples are given that demonstrate the use of functional MRI for clinical and research purposes. This development adds a new dimension to the application of magnetic resonance to medicine and physiology.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Combined 1H MR spectroscopy and diffusion-weighted MRI improves the prediction of stroke outcome.
M. W. Parsons, T. Li, P. A. Barber, Q. Yang, D. G. Darby, P. M. Desmond, R. P. Gerraty, B. M. Tress, and S. M. Davis (2000)
Neurology 55, 498-506
   Abstract »    Full Text »    PDF »
Magnetic resonance microscopy of embryonic cell lineages and movements.
R. Jacobs and S. Fraser (1994)
Science 263, 681-684
   Abstract »    PDF »
Functional mapping of the human visual cortex by magnetic resonance imaging.
J. Belliveau, D. Kennedy Jr, R. McKinstry, B. Buchbinder, R. Weisskoff, M. Cohen, J. Vevea, T. Brady, and B. Rosen (1991)
Science 254, 716-719
   Abstract »    PDF »
Echo-planar imaging: magnetic resonance imaging in a fraction of a second.
M. Stehling, R Turner, and P Mansfield (1991)
Science 254, 43-50
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)