Science 7 August 1992: Vol. 257. no. 5071, pp. 795 - 797 DOI: 10.1126/science.1323144

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Articles

Differential Expression of the Human CD8{beta} Splice Variants and Regulation of the M-2 Isoform by Ubiquitination.

D. Thakral, J. Dobbins, L. Devine, and P. B. Kavathas (2008)
J. Immunol. 180, 7431-7442
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Polymorphisms in the CD3Z Gene Influence TCR{zeta} Expression in Systemic Lupus Erythematosus Patients and Healthy Controls.

C. L. Gorman, A. I. Russell, Z. Zhang, D. Cunninghame Graham, A. P. Cope, and T. J. Vyse (2008)
J. Immunol. 180, 1060-1070
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Phosphorylation of Bcl10 Negatively Regulates T-Cell Receptor-Mediated NF-{kappa}B Activation.

H. Zeng, L. Di, G. Fu, Y. Chen, X. Gao, L. Xu, X. Lin, and R. Wen (2007)
Mol. Cell. Biol. 27, 5235-5245
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Seven-Transmembrane Receptors and Ubiquitination.

S. K. Shenoy (2007)
Circ. Res. 100, 1142-1154
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Role of Ubiquitylation in Cellular Membrane Transport.

O. Staub and D. Rotin (2006)
Physiol Rev 86, 669-707
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Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCR{zeta} for degradation.

M. D. Myers, L. L. Dragone, and A. Weiss (2005)
J. Cell Biol. 170, 285-294
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A Novel E3 Ubiquitin Ligase TRAC-1 Positively Regulates T Cell Activation.

H. Zhao, C. C. Li, J. Pardo, P. C. Chu, C. X. Liao, J. Huang, J. G. Dong, X. Zhou, Q. Huang, B. Huang, et al. (2005)
J. Immunol. 174, 5288-5297
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive and Ligand-Induced TCR Degradation.

M. von Essen, C. M. Bonefeld, V. Siersma, A. B. Rasmussen, J. P. H. Lauritsen, B. L. Nielsen, and C. Geisler (2004)
J. Immunol. 173, 384-393
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T Cell Receptor Engagement Leads to Phosphorylation of Clathrin Heavy Chain during Receptor Internalization.

V. L. Crotzer, A. S. Mabardy, A. Weiss, and F. M. Brodsky (2004)
J. Exp. Med. 199, 981-991
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The ubiquitin-proteasome system in cardiovascular diseases--a hypothesis extended.

J. Herrmann, A. Ciechanover, L. O Lerman, and A. Lerman (2004)
Cardiovasc Res 61, 11-21
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Cell Surface Expression of GluR5 Kainate Receptors Is Regulated by an Endoplasmic Reticulum Retention Signal.

Z. Ren, N. J. Riley, L. A. Needleman, J. M. Sanders, G. T. Swanson, and J. Marshall (2003)
J. Biol. Chem. 278, 52700-52709
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Allelic Exclusion of the TCR {alpha}-Chain Is an Active Process Requiring TCR-Mediated Signaling and c-Cbl.

N. Niederberger, K. Holmberg, S. M. Alam, W. Sakati, M. Naramura, H. Gu, and N. R. J. Gascoigne (2003)
J. Immunol. 170, 4557-4563
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Increased ubiquitin immunoreactivity in unstable atherosclerotic plaques associated with acute coronary syndromes.

J. Herrmann, W. D. Edwards, D. R. Holmes Jr, K. L. Shogren, L. O. Lerman, A. Ciechanover, and A. Lerman (2002)
J. Am. Coll. Cardiol. 40, 1919-1927
 |  Abstract »  |  Full Text »  |  PDF »

Positive Selection by the Pre-TCR Yields Mature CD8+ T Cells.

Y. Ito, S. Arai, N. S. C. van Oers, I. Aifantis, H. von Boehmer, and T. Miyazaki (2002)
J. Immunol. 169, 4913-4919
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Syk Tyrosine Kinase Is Required for c-Cbl-mediated Ubiquitination of Fcepsilon RI and Syk in RBL Cells.

R. Paolini, R. Molfetta, L. O. Beitz, J. Zhang, A. M. Scharenberg, M. Piccoli, L. Frati, R. Siraganian, and A. Santoni (2002)
J. Biol. Chem. 277, 36940-36947
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Endocytosis and Degradation of the Pre-T Cell Receptor.

M. Panigada, S. Porcellini, E. Barbier, S. Hoeflinger, P.-A. Cazenave, H. Gu, H. Band, H. von Boehmer, and F. Grassi (2002)
J. Exp. Med. 195, 1585-1597
 |  Abstract »  |  Full Text »  |  PDF »

The Cbl family of ubiquitin ligases: critical negative regulators of tyrosine kinase signaling in the immune system.

N. Rao, I. Dodge, and H. Band (2002)
J. Leukoc. Biol. 71, 753-763
 |  Abstract »  |  Full Text »  |  PDF »

The Ubiquitin-Proteasome Pathway Regulates the Availability of the GH Receptor.

P. van Kerkhof, M. Smeets, and G. J. Strous (2002)
Endocrinology 143, 1243-1252
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T Cell Development and T Cell Responses in Mice with Mutations Affecting Tyrosines 292 or 315 of the ZAP-70 Protein Tyrosine Kinase.

A. Magnan, V. Di Bartolo, A.-M. Mura, C. Boyer, M. Richelme, Y.-L. Lin, A. Roure, A. Gillet, C. Arrieumerlou, O. Acuto, et al. (2001)
J. Exp. Med. 194, 491-506
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Enhanced surface TCR replenishment mediated by CD28 leads to greater TCR engagement during primary stimulation.

A. G. Schrum, A. D. Wells, and L. A. Turka (2000)
Int. Immunol. 12, 833-842
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-Tau and Progesterone Regulate Ubiquitin Cross-Reactive Protein Expression in the Ovine Uterus.

G. A. Johnson, T. E. Spencer, R. C. Burghardt, M. M. Joyce, and F. W. Bazer (2000)
Biol Reprod 62, 622-627
 |  Abstract »  |  Full Text »

Induction of Ubiquitin-Conjugating Enzyme by Aggregated Low Density Lipoprotein in Human Macrophages and Its Implications for Atherosclerosis.

J. Kikuchi, Y. Furukawa, N. Kubo, A. Tokura, N. Hayashi, M. Nakamura, M. Matsuda, and I. Sakurabayashi (2000)
Arterioscler. Thromb. Vasc. Biol. 20, 128-134
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Interferon Tau Inducible Ubiquitin Cross-Reactive Protein in the Ovine Uterus.

G. A. Johnson, T. E. Spencer, T. R. Hansen, K. J. Austin, R. C. Burghardt, and F. W. Bazer (1999)
Biol Reprod 61, 312-318
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Biochemical Analysis of the Receptor for Ubiquitin-like Polypeptide.

M. Nakamura and Y. Tanigawa (1999)
J. Biol. Chem. 274, 18026-18032
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Perturbed Regulation of ZAP-70 and Sustained Tyrosine Phosphorylation of LAT and SLP-76 in c-Cbl-Deficient Thymocytes.

C. B. F. Thien, D. D. L. Bowtell, and W. Y. Langdon (1999)
J. Immunol. 162, 7133-7139
 |  Abstract »  |  Full Text »  |  PDF »

Caspase-mediated Degradation of T-Cell Receptor {{zeta}}-Chain.

B. R. Gastman, D. E. Johnson, T. L. Whiteside, and H. Rabinowich (1999)
Cancer Res. 59, 1422-1427
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The Extracellular Domain of the {zeta}-Chain Is Essential for TCR Function.

B. Johansson, E. Palmer, and L. Bolliger (1999)
J. Immunol. 162, 878-885
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The ubiquitin-proteasome system and endocytosis.

G. Strous and R Govers (1999)
J. Cell Sci. 112, 1417-1423
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Cbl-mediated Negative Regulation of the Syk Tyrosine Kinase. A CRITICAL ROLE FOR Cbl PHOSPHOTYROSINE-BINDING DOMAIN BINDING TO Syk PHOSPHOTYROSINE 323.

M. L. Lupher Jr., N. Rao, N. L. Lill, C. E. Andoniou, S. Miyake, E. A. Clark, B. Druker, and H. Band (1998)
J. Biol. Chem. 273, 35273-35281
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The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.

S. Miyake, M. L. Lupher Jr., B. Druker, and H. Band (1998)
PNAS 95, 7927-7932
 |  Abstract »  |  Full Text »  |  PDF »

Two Distinct Pathways Exist for Down-Regulation of the TCR.

J. P. H. Lauritsen, M. D. Christensen, J. Dietrich, J. Kastrup, N. Odum, and C. Geisler (1998)
J. Immunol. 161, 260-267
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Calnexin Associates with Monomeric and Oligomeric (Disulfide-linked) CD3delta Proteins in Murine T Lymphocytes.

K. P. Kearse (1998)
J. Biol. Chem. 273, 14152-14157
 |  Abstract »  |  Full Text »  |  PDF »

Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-dependent Removal from ER Membranes.

M. Yang, S. Omura, J. S. Bonifacino, and A. M. Weissman (1998)
J. Exp. Med. 187, 835-846
 |  Abstract »  |  Full Text »  |  PDF »

Elf-1 Regulates Basal Expression from the T Cell Antigen Receptor {zeta}-Chain Gene Promoter.

B. L. Rellahan, J. P. Jensen, T. K. Howcroft, D. S. Singer, E. Bonvini, and A. M. Weissman (1998)
J. Immunol. 160, 2794-2801
 |  Abstract »  |  Full Text »  |  PDF »

Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2.

L. Monney, I. Otter, R. Olivier, H. L. Ozer, A. L. Haas, S. Omura, and C. Borner (1998)
J. Biol. Chem. 273, 6121-6131
 |  Abstract »  |  Full Text »  |  PDF »

Cell Wall and Secreted Proteins of Candida albicans: Identification, Function, and Expression.

W. L. Chaffin, J. L. Lopez-Ribot, M. Casanova, D. Gozalbo, and J. P. Martinez (1998)
Microbiol. Mol. Biol. Rev. 62, 130-180
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mechanism for B Cell Repertoire Maturation Based on Response by B Cell Precursors to Pre-B Receptor Assembly.

R. Wasserman, Y.-S. Li, S.A. Shinton, C.E. Carmack, T. Manser, D.L. Wiest, K. Hayakawa, and R.R. Hardy (1998)
J. Exp. Med. 187, 259-264
 |  Abstract »  |  Full Text »  |  PDF »

Degradation of  T Cell Receptor (TCR)-CD3-zeta Complexes after Antigenic Stimulation.

S. Valitutti, S. Muller, M. Salio, and A. Lanzavecchia (1997)
J. Exp. Med. 185, 1859-1864
 |  Abstract »  |  Full Text »  |  PDF »

Growth Hormone-induced Signal Transduction Depends on an Intact Ubiquitin System.

G. J. Strous, P. van Kerkhof, R. Govers, P. Rotwein, and A. L. Schwartz (1997)
J. Biol. Chem. 272, 40-43
 |  Abstract »  |  Full Text »  |  PDF »

DUB-2 Is a Member of a Novel Family of Cytokine-inducible Deubiquitinating Enzymes.

Y. Zhu, K. Lambert, C. Corless, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, and A. D. D'Andrea (1997)
J. Biol. Chem. 272, 51-57
 |  Abstract »  |  Full Text »  |  PDF »

Normal T Cells Express Two T Cell Antigen Receptor Populations, One of Which Is Linked to the Cytoskeleton via zeta Chain and Displays a Unique Activation-dependent Phosphorylation Pattern.

S. Caplan and M. Baniyash (1996)
J. Biol. Chem. 271, 20705-20712
 |  Abstract »  |  Full Text »  |  PDF »

APP-BP1, a Novel Protein That Binds to the Carboxyl-terminal Region of the Amyloid Precursor Protein.

N. Chow, J. R. Korenberg, X.-N. Chen, and R. L. Neve (1996)
J. Biol. Chem. 271, 11339-11346
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Antigen Receptor Ubiquitination Is a Consequence of Receptor-mediated Tyrosine Kinase Activation.

C. Cenciarelli, K. G. Wilhelm Jr., A. Guo, and A. M. Weissman (1996)
J. Biol. Chem. 271, 8709-8713
 |  Abstract »  |  Full Text »  |  PDF »

Developmental Changes of the 26 S Proteasome in Abdominal Intersegmental Muscles of Manduca sexta during Programmed Cell Death.

S. P. Dawson, J. E. Arnold, N. J. Mayer, S. E. Reynolds, M. A. Billett, C. Gordon, L. Colleaux, P. M. Kloetzel, K. Tanaka, and R. J. Mayer (1995)
J. Biol. Chem. 270, 1850-1858
 |  Abstract »  |  Full Text »  |  PDF »

Surprising Signals in Plant Cells.

A. M. Jones (1994)
Science 263, 183-184
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Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains.

S Volarevic, B. Niklinska, C. Burns, C. June, A. Weissman, and J. Ashwell (1993)
Science 260, 541-544
 |  Abstract »  |  PDF »

The Proteasome Regulates Receptor-mediated Endocytosis of Interleukin-2.

A. Yu and T. R. Malek (2001)
J. Biol. Chem. 276, 381-385
 |  Abstract »  |  Full Text »  |  PDF »

Cbl Promotes Ubiquitination of the T Cell Receptor zeta through an Adaptor Function of Zap-70.

H.-Y. Wang, Y. Altman, D. Fang, C. Elly, Y. Dai, Y. Shao, and Y.-C. Liu (2001)
J. Biol. Chem. 276, 26004-26011
 |  Abstract »  |  Full Text »  |  PDF »

Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.

R. Paolini, R. Molfetta, M. Piccoli, L. Frati, and A. Santoni (2001)
PNAS 98, 9611-9616
 |  Abstract »  |  Full Text »  |  PDF »

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