Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Science Policy Alerts

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 16 July 1993:
Vol. 261. no. 5119, pp. 361 - 364
DOI: 10.1126/science.8392750
Prev | Table of Contents | Next

Articles

Science, Vol 261, Issue 5119, 361-364
Copyright © 1993 by American Association for the Advancement of Science

articles

Cellular mechanisms of a synchronized oscillation in the thalamus

M von Krosigk, T Bal, and DA McCormick

Section of Neurobiology, Yale University School of Medicine, New Haven, CT 06510.

Spindle waves are a prototypical example of synchronized oscillations, a common feature of neuronal activity in thalamic and cortical systems in sleeping and waking animals. Spontaneous spindle waves recorded from slices of the ferret lateral geniculate nucleus were generated by rebound burst firing in relay cells. This rebound burst firing resulted from inhibitory postsynaptic potentials arriving from the perigeniculate nucleus, the cells of which were activated by burst firing in relay neurons. Reduction of gamma-aminobutyric acidA (GABAA) receptor-mediated inhibition markedly enhanced GABAB inhibitory postsynaptic potentials in relay cells and subsequently generated a slowed and rhythmic population activity resembling that which occurs during an absence seizure. Pharmacological block of GABAB receptors abolished this seizure-like activity but not normal spindle waves, suggesting that GABAB antagonists may be useful in the treatment of absence seizures.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Excitatory and anti-oscillatory actions of nitric oxide in thalamus.
S. Yang and C. L. Cox (2008)
J. Physiol. 586, 3617-3628
   Abstract »    Full Text »    PDF »
Ablation of Kv3.1 and Kv3.3 Potassium Channels Disrupts Thalamocortical Oscillations In Vitro and In Vivo.
F. Espinosa, M. A. Torres-Vega, G. A. Marks, and R. H. Joho (2008)
J. Neurosci. 28, 5570-5581
   Abstract »    Full Text »    PDF »
Isoflurane Is a Potent Modulator of Extrasynaptic GABAA Receptors in the Thalamus.
F. Jia, M. Yue, D. Chandra, G. E. Homanics, P. A. Goldstein, and N. L. Harrison (2008)
J. Pharmacol. Exp. Ther. 324, 1127-1135
   Abstract »    Full Text »    PDF »
Pallidal Neuron Activity Increases during Sensory Relay through Thalamus in a Songbird Circuit Essential for Learning.
A. L. Person and D. J. Perkel (2007)
J. Neurosci. 27, 8687-8698
   Abstract »    Full Text »    PDF »
GABA Affinity Shapes IPSCs in Thalamic Nuclei.
C. M. Schofield and J. R. Huguenard (2007)
J. Neurosci. 27, 7954-7962
   Abstract »    Full Text »    PDF »
Reticular nucleus-specific changes in {alpha}3 subunit protein at GABA synapses in genetically epilepsy-prone rats.
X.-B. Liu, J. Coble, G. van Luijtelaar, and E. G. Jones (2007)
PNAS 104, 12512-12517
   Abstract »    Full Text »    PDF »
Neural Synchrony in Schizophrenia: From Networks to New Treatments.
J. M. Ford, J. H. Krystal, and D. H. Mathalon (2007)
Schizophr Bull 33, 848-852
   Abstract »    Full Text »    PDF »
Heterogeneity of firing properties among rat thalamic reticular nucleus neurons.
S.-H. Lee, G. Govindaiah, and C. L. Cox (2007)
J. Physiol. 582, 195-208
   Abstract »    Full Text »    PDF »
Modulation of Inhibitory Activity by Nitric Oxide in the Thalamus.
S. Yang and C. L. Cox (2007)
J Neurophysiol 97, 3386-3395
   Abstract »    Full Text »    PDF »
Giant Spontaneous Depolarizing Potentials in the Developing Thalamic Reticular Nucleus.
S. Pangratz-Fuehrer, U. Rudolph, and J. R. Huguenard (2007)
J Neurophysiol 97, 2364-2372
   Abstract »    Full Text »    PDF »
Metabotropic Glutamate Receptors Differentially Regulate GABAergic Inhibition in Thalamus.
G. Govindaiah and C. L. Cox (2006)
J. Neurosci. 26, 13443-13453
   Abstract »    Full Text »    PDF »
Nucleus-Specific Abnormalities of GABAergic Synaptic Transmission in a Genetic Model of Absence Seizures.
T. Bessaih, L. Bourgeais, C. I. Badiu, D. A. Carter, T. I. Toth, D. Ruano, B. Lambolez, V. Crunelli, and N. Leresche (2006)
J Neurophysiol 96, 3074-3081
   Abstract »    Full Text »    PDF »
Mechanism of Increased Open Probability by a Mutation of the BK Channel.
A. Diez-Sampedro, W. R. Silverman, J. F. Bautista, and G. B. Richerson (2006)
J Neurophysiol 96, 1507-1516
   Abstract »    Full Text »    PDF »
Distinct Electrical and Chemical Connectivity Maps in the Thalamic Reticular Nucleus: Potential Roles in Synchronization and Sensation..
C. Deleuze and J. R. Huguenard (2006)
J. Neurosci. 26, 8633-8645
   Abstract »    Full Text »    PDF »
Excitatory Actions of Vasoactive Intestinal Peptide on Mouse Thalamocortical Neurons Are Mediated by VPAC2 Receptors.
S.-H. Lee and C. L. Cox (2006)
J Neurophysiol 96, 858-871
   Abstract »    Full Text »    PDF »
Corticothalamic 5-9 Hz oscillations are more pro-epileptogenic than sleep spindles in rats.
D. Pinault, A. Slezia, and L. Acsady (2006)
J. Physiol. 574, 209-227
   Abstract »    Full Text »    PDF »
Intrinsic and synaptic dynamics interact to generate emergent patterns of rhythmic bursting in thalamocortical neurons..
V. S. Sohal, S. Pangratz-Fuehrer, U. Rudolph, and J. R. Huguenard (2006)
J. Neurosci. 26, 4247-4255
   Abstract »    Full Text »    PDF »
Fast IPSCs in rat thalamic reticular nucleus require the GABAA receptor {beta}1 subunit.
M. M. Huntsman and J. R. Huguenard (2006)
J. Physiol. 572, 459-475
   Abstract »    Full Text »    PDF »
Coding of Stimulus Frequency by Latency in Thalamic Networks Through the Interplay of GABAB-Mediated Feedback and Stimulus Shape.
D. Golomb, E. Ahissar, and D. Kleinfeld (2006)
J Neurophysiol 95, 1735-1750
   Abstract »    Full Text »    PDF »
Inhibitory coupling specifically generates emergent gamma oscillations in diverse cell types.
V. S. Sohal and J. R. Huguenard (2005)
PNAS 102, 18638-18643
   Abstract »    Full Text »    PDF »
Photic-Induced Sensitization: Acquisition of an Augmenting Spike-Wave Response in the Adult Rat Through Repeated Strobe Exposure.
D. J. Uhlrich, K. A. Manning, M. L. O'Laughlin, and W. W. Lytton (2005)
J Neurophysiol 94, 3925-3937
   Abstract »    Full Text »    PDF »
Thalamic Mechanisms of EEG Alpha Rhythms and Their Pathological Implications.
S. W. Hughes and V. Crunelli (2005)
Neuroscientist 11, 357-372
   Abstract »    PDF »
Single-Column Thalamocortical Network Model Exhibiting Gamma Oscillations, Sleep Spindles, and Epileptogenic Bursts.
R. D. Traub, D. Contreras, M. O. Cunningham, H. Murray, F. E. N. LeBeau, A. Roopun, A. Bibbig, W. B. Wilent, M. J. Higley, and M. A. Whittington (2005)
J Neurophysiol 93, 2194-2232
   Abstract »    Full Text »    PDF »
Excitatory Effects of Thyrotropin-Releasing Hormone in the Thalamus.
C. Broberger and D. A. McCormick (2005)
J. Neurosci. 25, 1664-1673
   Abstract »    Full Text »    PDF »
Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep.
M. P. Anderson, T. Mochizuki, J. Xie, W. Fischler, J. P. Manger, E. M. Talley, T. E. Scammell, and S. Tonegawa (2005)
PNAS 102, 1743-1748
   Abstract »    Full Text »    PDF »
Membrane Bistability in Thalamic Reticular Neurons During Spindle Oscillations.
P. Fuentealba, I. Timofeev, M. Bazhenov, T. J. Sejnowski, and M. Steriade (2005)
J Neurophysiol 93, 294-304
   Abstract »    Full Text »    PDF »
Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking {alpha}1G-subunit of T-type calcium channels.
J. Lee, D. Kim, and H.-S. Shin (2004)
PNAS 101, 18195-18199
   Abstract »    Full Text »    PDF »
From The Cover: Prolonged hyperpolarizing potentials precede spindle oscillations in the thalamic reticular nucleus.
P. Fuentealba, I. Timofeev, and M. Steriade (2004)
PNAS 101, 9816-9821
   Abstract »    Full Text »    PDF »
Corticofugal Gating of Auditory Information in the Thalamus: An In Vivo Intracellular Recording Study.
Y.-Q. Yu, Y. Xiong, Y.-S. Chan, and J. He (2004)
J. Neurosci. 24, 3060-3069
   Abstract »    Full Text »    PDF »
Corticothalamic Inhibition in the Thalamic Reticular Nucleus.
L. Zhang and E. G. Jones (2004)
J Neurophysiol 91, 759-766
   Abstract »    Full Text »    PDF »
Small Clusters of Electrically Coupled Neurons Generate Synchronous Rhythms in the Thalamic Reticular Nucleus.
M. A. Long, C. E. Landisman, and B. W. Connors (2004)
J. Neurosci. 24, 341-349
   Abstract »    Full Text »    PDF »
Target-Specific Neuropeptide Y-Ergic Synaptic Inhibition and Its Network Consequences within the Mammalian Thalamus.
Q.-Q. Sun, S. C. Baraban, D. A. Prince, and J. R. Huguenard (2003)
J. Neurosci. 23, 9639-9649
   Abstract »    Full Text »    PDF »
Inhibitory Interconnections Control Burst Pattern and Emergent Network Synchrony in Reticular Thalamus.
V. S. Sohal and J. R. Huguenard (2003)
J. Neurosci. 23, 8978-8988
   Abstract »    Full Text »    PDF »
Interactions Between Membrane Conductances Underlying Thalamocortical Slow-Wave Oscillations.
A. DESTEXHE and T. J. SEJNOWSKI (2003)
Physiol Rev 83, 1401-1453
   Abstract »    Full Text »    PDF »
Slow Oscillation in Non-Lemniscal Auditory Thalamus.
J. He (2003)
J. Neurosci. 23, 8281-8290
   Abstract »    Full Text »    PDF »
Vasoactive Intestinal Peptide Selectively Depolarizes Thalamic Relay Neurons and Attenuates Intrathalamic Rhythmic Activity.
S.-H. Lee and C. L. Cox (2003)
J Neurophysiol 90, 1224-1234
   Abstract »    Full Text »    PDF »
Effects of Ventrobasal Lesion and Cortical Cooling on Fast Oscillations (>200 Hz) in Rat Somatosensory Cortex.
R. J. Staba, B. Brett-Green, M. Paulsen, and D. S. Barth (2003)
J Neurophysiol 89, 2380-2388
   Abstract »    Full Text »    PDF »
Dynamic GABAA Receptor Subtype-Specific Modulation of the Synchrony and Duration of Thalamic Oscillations.
V. S. Sohal, R. Keist, U. Rudolph, and J. R. Huguenard (2003)
J. Neurosci. 23, 3649-3657
   Abstract »    Full Text »    PDF »
Actions of U-92032, a T-Type Ca2+ Channel Antagonist, Support a Functional Linkage Between IT and Slow Intrathalamic Rhythms.
D. M. Porcello, S. D. Smith, and J. R. Huguenard (2003)
J Neurophysiol 89, 177-185
   Abstract »    Full Text »    PDF »
Model of Thalamocortical Slow-Wave Sleep Oscillations and Transitions to Activated States.
M. Bazhenov, I. Timofeev, M. Steriade, and T. J. Sejnowski (2002)
J. Neurosci. 22, 8691-8704
   Abstract »    Full Text »    PDF »
Inhibitory Synchronization of Bursting in Biological Neurons: Dependence on Synaptic Time Constant.
R. C. Elson, A. I. Selverston, H. D. I. Abarbanel, and M. I. Rabinovich (2002)
J Neurophysiol 88, 1166-1176
   Abstract »    Full Text »    PDF »
Involvement of Calcium in Rhythmic Activity Induced by Disinhibition in Cultured Spinal Cord Networks.
P. Darbon, C. Pignier, E. Niggli, and J. Streit (2002)
J Neurophysiol 88, 1461-1468
   Abstract »    Full Text »    PDF »
In vitro networks: cortical mechanisms of anaesthetic action.
B. Antkowiak (2002)
Br. J. Anaesth. 89, 102-111
   Abstract »    Full Text »    PDF »
Somatostatin Inhibits Thalamic Network Oscillations In Vitro: Actions on the GABAergic Neurons of the Reticular Nucleus.
Q.-Q. Sun, J. R. Huguenard, and D. A. Prince (2002)
J. Neurosci. 22, 5374-5386
   Abstract »    Full Text »    PDF »
Neuromodulatory Role of Serotonin in the Ferret Thalamus.
J. E. Monckton and D. A. McCormick (2002)
J Neurophysiol 87, 2124-2136
   Abstract »    Full Text »    PDF »
Disruption of GABAA Receptors on GABAergic Interneurons Leads to Increased Oscillatory Power in the Olfactory Bulb Network.
Z. Nusser, L. M. Kay, G. Laurent, G. E. Homanics, and I. Mody (2001)
J Neurophysiol 86, 2823-2833
   Abstract »    Full Text »    PDF »
Gap Junctions between Interneuron Dendrites Can Enhance Synchrony of Gamma Oscillations in Distributed Networks.
R. D. Traub, N. Kopell, A. Bibbig, E. H. Buhl, F. E. N. LeBeau, and M. A. Whittington (2001)
J. Neurosci. 21, 9478-9486
   Abstract »    Full Text »    PDF »
Kinetic and Pharmacological Properties of GABAA Receptors in Single Thalamic Neurons and GABAA Subunit Expression.
S. H. Browne, J. Kang, G. Akk, L. W. Chiang, H. Schulman, J. R. Huguenard, and D. A. Prince (2001)
J Neurophysiol 86, 2312-2322
   Abstract »    Full Text »    PDF »
GABAB and NMDA Receptors Contribute to Spindle-Like Oscillations in Rat Thalamus In Vitro.
R. B. Jacobsen, D. Ulrich, and J. R. Huguenard (2001)
J Neurophysiol 86, 1365-1375
   Abstract »    Full Text »    PDF »
Impact of Network Activities on Neuronal Properties in Corticothalamic Systems.
M. Steriade (2001)
J Neurophysiol 86, 1-39
   Abstract »    Full Text »    PDF »
Origin of Synchronized Oscillations Induced by Neocortical Disinhibition In Vivo.
M. A. Castro-Alamancos (2000)
J. Neurosci. 20, 9195-9206
   Abstract »    Full Text »    PDF »
Cortical Feedback Controls the Frequency and Synchrony of Oscillations in the Visual Thalamus.
T. Bal, D. Debay, and A. Destexhe (2000)
J. Neurosci. 20, 7478-7488
   Abstract »    Full Text »    PDF »
Spiking-Bursting Activity in the Thalamic Reticular Nucleus Initiates Sequences of Spindle Oscillations in Thalamic Networks.
M. Bazhenov, I. Timofeev, M. Steriade, and T. Sejnowski (2000)
J Neurophysiol 84, 1076-1087
   Abstract »    Full Text »    PDF »
Increased Synchrony with Increase of a Low-Threshold Calcium Conductance in a Model Thalamic Network: A Phase-Shift Mechanism.
E. Thomas and T. Grisar (2000)
Neural Comput. 12, 1553-1571
   Abstract »    Full Text »
Corticothalamic Inputs Control the Pattern of Activity Generated in Thalamocortical Networks.
H. Blumenfeld and D. A. McCormick (2000)
J. Neurosci. 20, 5153-5162
   Abstract »    Full Text »    PDF »
Sleep, Memory Maintenance, and Mental Disorders.
J. L. Kavanau (2000)
J Neuropsychiatry Clin Neurosci 12, 199-208
   Abstract »    Full Text »    PDF »
Regionally Selective Blockade of GABAergic Inhibition by Zinc in the Thalamocortical System: Functional Significance.
J. W. Gibbs III, Y.-F. Zhang, M. D. Shumate, and D. A. Coulter (2000)
J Neurophysiol 83, 1510-1521
   Abstract »    Full Text »    PDF »
Reciprocal Inhibitory Connections Regulate the Spatiotemporal Properties of Intrathalamic Oscillations.
V. S. Sohal, M. M. Huntsman, and J. R. Huguenard (2000)
J. Neurosci. 20, 1735-1745
   Abstract »    Full Text »    PDF »
Action Potential Backpropagation and Somato-dendritic Distribution of Ion Channels in Thalamocortical Neurons.
S. R. Williams and G. J. Stuart (2000)
J. Neurosci. 20, 1307-1317
   Abstract »    Full Text »    PDF »
Nucleus-Specific Differences in GABAA-Receptor-Mediated Inhibition Are Enhanced During Thalamic Development.
M. M. Huntsman and J. R. Huguenard (2000)
J Neurophysiol 83, 350-358
   Abstract »    Full Text »    PDF »
Control of Action Potential Timing by Intrinsic Subthreshold Oscillations in Olfactory Bulb Output Neurons.
D. Desmaisons, J.-D. Vincent, and P.-M. Lledo (1999)
J. Neurosci. 19, 10727-10737
   Abstract »    Full Text »    PDF »
Continuous and lurching traveling pulses in neuronal networks with delay and spatially decaying connectivity.
D. Golomb and G. B. Ermentrout (1999)
PNAS 96, 13480-13485
   Abstract »    Full Text »    PDF »
Increased gamma - and Decreased delta -Oscillations in a Mouse Deficient for a Potassium Channel Expressed in Fast-Spiking Interneurons.
R. H. Joho, C. S. Ho, and G. A. Marks (1999)
J Neurophysiol 82, 1855-1864
   Abstract »    Full Text »    PDF »
Three GABA Receptor-Mediated Postsynaptic Potentials in Interneurons in the Rat Lateral Geniculate Nucleus.
J. J. Zhu and F.-S. Lo (1999)
J. Neurosci. 19, 5721-5730
   Abstract »    Full Text »    PDF »
Brain Mechanisms of Propofol-Induced Loss of Consciousness in Humans: a Positron Emission Tomographic Study.
P. Fiset, T. Paus, T. Daloze, G. Plourde, P. Meuret, V. Bonhomme, N. Hajj-Ali, S. B. Backman, and A. C. Evans (1999)
J. Neurosci. 19, 5506-5513
   Abstract »    Full Text »    PDF »
Excitatory But Not Inhibitory Synaptic Transmission Is Reduced in Lethargic (Cacnb4lh) and Tottering (Cacna1atg) Mouse Thalami.
S. J. Caddick, C. Wang, C. F. Fletcher, N. A. Jenkins, N. G. Copeland, and D. A. Hosford (1999)
J Neurophysiol 81, 2066-2074
   Abstract »    Full Text »    PDF »
Encoding of Visual Information by LGN Bursts.
P. Reinagel, D. Godwin, S. M. Sherman, and C. Koch (1999)
J Neurophysiol 81, 2558-2569
   Abstract »    Full Text »    PDF »
An Intrinsic Oscillation in Interneurons of the Rat Lateral Geniculate Nucleus.
J. J. Zhu, W. W. Lytton, J.-T. Xue, and D. J. Uhlrich (1999)
J Neurophysiol 81, 702-711
   Abstract »    Full Text »    PDF »
Reciprocal Inhibitory Connections and Network Synchrony in the Mammalian Thalamus.
M. M. Huntsman, D. M. Porcello, G. E. Homanics, T. M. DeLorey, and J. R. Huguenard (1999)
Science 283, 541-543
   Abstract »    Full Text »
Absence Seizures Decrease Steroid Modulation of t-[35S]Butylbicyclophosphorothionate Binding in Thalamic Relay Nuclei.
P. K. Banerjee, R. W. Olsen, N. J. K. Tillakaratne, S. Brailowsky, A. J. Tobin, and O. C. Snead III (1998)
J. Pharmacol. Exp. Ther. 287, 766-772
   Abstract »    Full Text »
Spike-and-Wave Oscillations Based on the Properties of GABAB Receptors.
A. Destexhe (1998)
J. Neurosci. 18, 9099-9111
   Abstract »    Full Text »    PDF »
Long-Range Connections Synchronize Rather Than Spread Intrathalamic Oscillations: Computational Modeling and In Vitro Electrophysiology.
V. S. Sohal and J. R. Huguenard (1998)
J Neurophysiol 80, 1736-1751
   Abstract »    Full Text »    PDF »
Functional and Ionic Properties of a Slow Afterhyperpolarization in Ferret Perigeniculate Neurons In Vitro.
U. Kim and D. A. Mccormick (1998)
J Neurophysiol 80, 1222-1235
   Abstract »    Full Text »    PDF »
Effect of Bicuculline on Thalamic Activity: A Direct Blockade of IAHP in Reticularis Neurons.
F. Debarbieux, J. Brunton, and S. Charpak (1998)
J Neurophysiol 79, 2911-2918
   Abstract »    Full Text »    PDF »
Periodicity of Thalamic Spindle Waves Is Abolished by ZD7288,a Blocker of Ih.
A. Luthi, T. Bal, and D. A. McCormick (1998)
J Neurophysiol 79, 3284-3289
   Abstract »    Full Text »    PDF »
Dendritic Low-Threshold Calcium Currents in Thalamic Relay Cells.
A. Destexhe, M. Neubig, D. Ulrich, and J. Huguenard (1998)
J. Neurosci. 18, 3574-3588
   Abstract »    Full Text »    PDF »
Propagating Activity Patterns in Large-Scale Inhibitory Neuronal Networks.
J. Rinzel, D. Terman, X. Wang, and B. Ermentrout (1998)
Science 279, 1351-1355
   Abstract »    Full Text »
Mechanisms Underlying the Synchronizing Action of Corticothalamic Feedback Through Inhibition of Thalamic Relay Cells.
A. Destexhe, D. Contreras, and M. Steriade (1998)
J Neurophysiol 79, 999-1016
   Abstract »    Full Text »    PDF »
Slow Synaptic Inhibition in Nucleus HVc of the Adult Zebra Finch.
M. F. Schmidt and D. J. Perkel (1998)
J. Neurosci. 18, 895-904
   Abstract »    Full Text »    PDF »
Functional Properties of Perigeniculate Inhibition of Dorsal Lateral Geniculate Nucleus Thalamocortical Neurons In Vitro.
M. V. Sanchez-Vives and D. A. McCormick (1997)
J. Neurosci. 17, 8880-8893
   Abstract »    Full Text »    PDF »
Inhibitory Interactions between Perigeniculate GABAergic Neurons.
M. V. Sanchez-Vives, T. Bal, and D. A. McCormick (1997)
J. Neurosci. 17, 8894-8908
   Abstract »    Full Text »    PDF »
GABAA Receptor-Mediated Cl- Currents in Rat Thalamic Reticular and Relay Neurons.
S. J. Zhang, J. R. Huguenard, and D. A. Prince (1997)
J Neurophysiol 78, 2280-2286
   Abstract »    Full Text »    PDF »
Shaping of IPSCs by Endogenous Calcineurin Activity.
M. V. Jones and G. L. Westbrook (1997)
J. Neurosci. 17, 7626-7633
   Abstract »    Full Text »    PDF »
Functional Dynamics of GABAergic Inhibition in the Thalamus.
U. Kim, M. V. Sanchez-Vives, and D. A. McCormick (1997)
Science 278, 130-134
   Abstract »    Full Text »
GABAA-Receptor-Mediated Rebound Burst Firing and Burst Shunting in Thalamus.
D. Ulrich and J. R. Huguenard (1997)
J Neurophysiol 78, 1748-1751
   Abstract »    Full Text »    PDF »
Nucleus reticularis neurons mediate diverse inhibitory effects in thalamus.
C. L. Cox, J. R. Huguenard, and D. A. Prince (1997)
PNAS 94, 8854-8859
   Abstract »    Full Text »    PDF »
Regional Cerebral Blood Flow Changes as a Function of Delta and Spindle Activity during Slow Wave Sleep in Humans.
N. Hofle, T. Paus, D. Reutens, P. Fiset, J. Gotman, A. C. Evans, and B. E. Jones (1997)
J. Neurosci. 17, 4800-4808
   Abstract »    Full Text »    PDF »
Short-Term Plasticity during Intrathalamic Augmenting Responses in Decorticated Cats.
M. Steriade and I. Timofeev (1997)
J. Neurosci. 17, 3778-3795
   Abstract »    Full Text »    PDF »
Dynamic Interactions Determine Partial Thalamic Quiescence in a Computer Network Model of Spike-and-Wave Seizures.
W. W. Lytton, D. Contreras, A. Destexhe, and M. Steriade (1997)
J Neurophysiol 77, 1679-1696
   Abstract »    Full Text »    PDF »
Nucleus-Specific Chloride Homeostasis in Rat Thalamus.
D. Ulrich and J. R. Huguenard (1997)
J. Neurosci. 17, 2348-2354
   Abstract »    Full Text »    PDF »
Spatiotemporal Patterns of Spindle Oscillations in Cortex and Thalamus.
D. Contreras, A. Destexhe, T. J. Sejnowski, and M. Steriade (1997)
J. Neurosci. 17, 1179-1196
   Abstract »    Full Text »    PDF »
Peptidergic Modulation of Intrathalamic Circuit Activity In Vitro: Actions of Cholecystokinin.
C. L. Cox, J. R. Huguenard, and D. A. Prince (1997)
J. Neurosci. 17, 70-82
   Abstract &raq