Science 19 November 1993: Vol. 262. no. 5137, pp. 1274 - 1277 DOI: 10.1126/science.8235659

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Articles

Bcl-2-family proteins and hematologic malignancies: history and future prospects.

J. C. Reed (2008)
Blood 111, 3322-3330
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Old Yellow Enzymes, Highly Homologous FMN Oxidoreductases with Modulating Roles in Oxidative Stress and Programmed Cell Death in Yeast.

O. Odat, S. Matta, H. Khalil, S. C. Kampranis, R. Pfau, P. N. Tsichlis, and A. M. Makris (2007)
J. Biol. Chem. 282, 36010-36023
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Glutathione Binding to the Bcl-2 Homology-3 Domain Groove: A MOLECULAR BASIS FOR BCL-2 ANTIOXIDANT FUNCTION AT MITOCHONDRIA.

A. K. Zimmermann, F. A. Loucks, E. K. Schroeder, R. J. Bouchard, K. L. Tyler, and D. A. Linseman (2007)
J. Biol. Chem. 282, 29296-29304
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The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility.

I.M.W. Ebisch, C.M.G. Thomas, W.H.M. Peters, D.D.M. Braat, and R.P.M. Steegers-Theunissen (2007)
Hum. Reprod. Update 13, 163-174
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Activation of Peroxisome Proliferator-Activated Receptor {gamma} Contributes to the Survival of T Lymphoma Cells by Affecting Cellular Metabolism.

C. Yang, S.-H. Jo, B. Csernus, E. Hyjek, Y. Liu, A. Chadburn, and Y. L. Wang (2007)
Am. J. Pathol. 170, 722-732
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Hyperglycemia Inhibits Retinoic Acid-Induced Activation of Rac1, Prevents Differentiation of Cortical Neurons, and Causes Oxidative Stress in a Rat Model of Diabetic Pregnancy.

R. S. Guleria, J. Pan, D. DiPette, and U. S. Singh (2006)
Diabetes 55, 3326-3334
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Redox-Induced Apoptosis of Human Oocytes in Resting Follicles In Vitro.

X. Zhang, X.-H. Li, X. Ma, Z.-H. Wang, S. Lu, and Y.-L. Guo (2006)
Reproductive Sciences 13, 451-458
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The effect of Mentha spicata Labiatae on uterine tissue in rats.

M. Guney, B. Oral, N. Karahanli, T. Mungan, and M. Akdogan (2006)
Toxicology and Industrial Health 22, 343-348
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Free radical biology and medicine: it's a gas, man!.

W. A. Pryor, K. N. Houk, C. S. Foote, J. M. Fukuto, L. J. Ignarro, G. L. Squadrito, and K. J. A. Davies (2006)
Am J Physiol Regulatory Integrative Comp Physiol 291, R491-R511
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The Long-Term Effect of Sevoflurane on Neuronal Cell Damage and Expression of Apoptotic Factors After Cerebral Ischemia and Reperfusion in Rats..

M. Pape, K. Engelhard, E. Eberspacher, R. Hollweck, K. Kellermann, S. Zintner, P. Hutzler, and C. Werner (2006)
Anesth. Analg. 103, 173-179
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Inhibition of Glutathione Synthesis Overcomes Bcl-2-Mediated Topoisomerase Inhibitor Resistance and Induces Nonapoptotic Cell Death via Mitochondrial-Independent Pathway.

A. Yoshida, H. Takemura, H. Inoue, T. Miyashita, and T. Ueda (2006)
Cancer Res. 66, 5772-5780
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Cilostazol Protects Against Brain White Matter Damage and Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion.

T. Watanabe, N. Zhang, M. Liu, R. Tanaka, Y. Mizuno, and T. Urabe (2006)
Stroke 37, 1539-1545
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Selenium Supplementation Restores the Antioxidative Capacity and Prevents Cell Damage in Bone Marrow Stromal Cells In Vitro.

R. Ebert, M. Ulmer, S. Zeck, J. Meissner-Weigl, D. Schneider, H. Stopper, N. Schupp, M. Kassem, and F. Jakob (2006)
Stem Cells 24, 1226-1235
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In vivo hyperoxic preconditioning prevents myocardial infarction by expressing bcl-2..

H. Choi, S.-H. Kim, Y.-S. Chun, Y.-S. Cho, J.-W. Park, and M.-S. Kim (2006)
Experimental Biology and Medicine 231, 463-472
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Bcl-2 and Mn-SOD Antisense Oligodeoxynucleotides and a Glutamine-enriched Diet Facilitate Elimination of Highly Resistant B16 Melanoma Cells by Tumor Necrosis Factor-{alpha} and Chemotherapy.

M. Benlloch, S. Mena, P. Ferrer, E. Obrador, M. Asensi, J. A. Pellicer, J. Carretero, A. Ortega, and J. M. Estrela (2006)
J. Biol. Chem. 281, 69-79
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Reactive oxygen species production by mitochondria in endothelial cells exposed to reoxygenation after hypoxia and glucose depletion is mediated by ceramide.

S. Therade-Matharan, E. Laemmel, S. Carpentier, Y. Obata, T. Levade, J. Duranteau, and E. Vicaut (2005)
Am J Physiol Regulatory Integrative Comp Physiol 289, R1756-R1762
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Neuroprotective Effect of Sulfhydryl Reduction in a Rat Optic Nerve Crush Model.

K. I. Swanson, C. R. Schlieve, C. J. Lieven, and L. A. Levin (2005)
Invest. Ophthalmol. Vis. Sci. 46, 3737-3741
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MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.

Y. Liu, G. L. Borchert, S. P. Donald, A. Surazynski, C.-A. Hu, C. J. Weydert, L. W. Oberley, and J. M. Phang (2005)
Carcinogenesis 26, 1335-1342
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Neurotrophic Agent, T-817MA [1-{3-[2-(1-Benzothiophen-5-yl) Ethoxy] Propyl}-3-azetidinol Maleate], Attenuates Amyloid-{beta}-Induced Neurotoxicity and Promotes Neurite Outgrowth in Rat Cultured Central Nervous System Neurons.

K. Hirata, H. Yamaguchi, Y. Takamura, A. Takagi, T. Fukushima, N. Iwakami, A. Saitoh, M. Nakagawa, and T. Yamada (2005)
J. Pharmacol. Exp. Ther. 314, 252-259
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Role of Intracellular Glutathione in Cell Sensitivity to the Apoptosis Induced by Tumor Necrosis Factor {alpha}-Related Apoptosis-Inducing Ligand/Anticancer Drug Combinations.

O. Meurette, L. Lefeuvre-Orfila, A. Rebillard, D. Lagadic-Gossmann, and M.-T. Dimanche-Boitrel (2005)
Clin. Cancer Res. 11, 3075-3083
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Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast.

A. I. Pozniakovsky, D. A. Knorre, O. V. Markova, A. A. Hyman, V. P. Skulachev, and F. F. Severin (2005)
J. Cell Biol. 168, 257-269
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Inhibition of Transcription Factor Activity by Nuclear Compartment-associated Bcl-2.

C. A. Massaad, B. P. Portier, and G. Taglialatela (2004)
J. Biol. Chem. 279, 54470-54478
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Caspase-Independent Cell Death by Arsenic Trioxide in Human Cervical Cancer Cells: Reactive Oxygen Species-Mediated Poly(ADP-ribose) Polymerase-1 Activation Signals Apoptosis-Inducing Factor Release from Mitochondria.

Y.-H. Kang, M.-J. Yi, M.-J. Kim, M.-T. Park, S. Bae, C.-M. Kang, C.-K. Cho, I.-C. Park, M.-J. Park, C. H. Rhee, et al. (2004)
Cancer Res. 64, 8960-8967
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Supplementation of Endothelial Cells with Mitochondria-targeted Antioxidants Inhibit Peroxide-induced Mitochondrial Iron Uptake, Oxidative Damage, and Apoptosis.

A. Dhanasekaran, S. Kotamraju, S. V. Kalivendi, T. Matsunaga, T. Shang, A. Keszler, J. Joseph, and B. Kalyanaraman (2004)
J. Biol. Chem. 279, 37575-37587
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A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.

R. M. Graham, D. P. Frazier, J. W. Thompson, S. Haliko, H. Li, B. J. Wasserlauf, M.-G. Spiga, N. H. Bishopric, and K. A. Webster (2004)
J. Exp. Biol. 207, 3189-3200
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Murine Models of Life Span Extension.

J. K. Quarrie and K. T. Riabowol (2004)
Sci. Aging Knowl. Environ. 2004, re5
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Infection with Oncolytic Herpes Simplex Virus-1 Induces Apoptosis in Neighboring Human Cancer Cells: A Potential Target to Increase Anticancer Activity.

S. F. Stanziale, H. Petrowsky, P. S. Adusumilli, L. Ben-Porat, M. Gonen, and Y. Fong (2004)
Clin. Cancer Res. 10, 3225-3232
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Bcl-xL and E1B-19K Proteins Inhibit p53-induced Irreversible Growth Arrest and Senescence by Preventing Reactive Oxygen Species-dependent p38 Activation.

M.-S. Jung, D.-H. Jin, H.-D. Chae, S. Kang, S.-C. Kim, Y.-J. Bang, T.-S. Choi, K.-s. Choi, and D. Y. Shin (2004)
J. Biol. Chem. 279, 17765-17771
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Tumor Necrosis Factor-{alpha}-Induced Apoptosis of Human Coronary Artery Endothelial Cells: Modulation by the Peroxisome Proliferator-Activated Receptor-{gamma} Ligand Pioglitazone.

J. Chen, D. Li, X. Zhang, and J. L. Mehta (2004)
Journal of Cardiovascular Pharmacology and Therapeutics 9, 35-41
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Role of Caspases in Ox-LDL-Induced Apoptotic Cascade in Human Coronary Artery Endothelial Cells.

J. Chen, J. L. Mehta, N. Haider, X. Zhang, J. Narula, and D. Li (2004)
Circ. Res. 94, 370-376
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Protection against Murine Leukemia Virus-Induced Spongiform Myeloencephalopathy in Mice Overexpressing Bcl-2 but Not in Mice Deficient for Interleukin-6, Inducible Nitric Oxide Synthetase, ICE, Fas, Fas Ligand, or TNF-R1 Genes.

P. Jolicoeur, C. Hu, T. W. Mak, J.-C. Martinou, and D. G. Kay (2003)
J. Virol. 77, 13161-13170
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Melanoma Differentiation Associated Gene-7, mda-7/Interleukin-24, Induces Apoptosis in Prostate Cancer Cells by Promoting Mitochondrial Dysfunction and Inducing Reactive Oxygen Species.

I. V. Lebedeva, Z.-Z. Su, D. Sarkar, S. Kitada, P. Dent, S. Waxman, J. C. Reed, and P. B. Fisher (2003)
Cancer Res. 63, 8138-8144
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Schizosaccharomyces pombe Cells Deficient in Triacylglycerols Synthesis Undergo Apoptosis upon Entry into the Stationary Phase.

Q. Zhang, H. K. Chieu, C. P. Low, S. Zhang, C. K. Heng, and H. Yang (2003)
J. Biol. Chem. 278, 47145-47155
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Astrocyte Protection of Neurons: ROLE OF TRANSFORMING GROWTH FACTOR-{beta} SIGNALING VIA A c-Jun-AP-1 PROTECTIVE PATHWAY.

K. M. Dhandapani, M. Hadman, L. De Sevilla, M. F. Wade, V. B. Mahesh, and D. W. Brann (2003)
J. Biol. Chem. 278, 43329-43339
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Down-regulation of Glutathione and Bcl-2 Synthesis in Mouse B16 Melanoma Cells Avoids Their Survival during Interaction with the Vascular Endothelium.

A. Ortega, P. Ferrer, J. Carretero, E. Obrador, M. Asensi, J. A. Pellicer, and J. M. Estrela (2003)
J. Biol. Chem. 278, 39591-39599
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Involvement of the VDE Homing Endonuclease and Rapamycin in Regulation of the Saccharomyces cerevisiae GSH11 Gene Encoding the High Affinity Glutathione Transporter.

T. Miyake, H. Hiraishi, H. Sammoto, and B.-I. Ono (2003)
J. Biol. Chem. 278, 39632-39636
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Evidence for the Role of a Peroxidase Compound I-type Intermediate in the Oxidation of Glutathione, NADH, Ascorbate, and Dichlorofluorescin by Cytochrome c/H2O2: IMPLICATIONS FOR OXIDATIVE STRESS DURING APOPTOSIS.

A. Lawrence, C. M. Jones, P. Wardman, and M. J. Burkitt (2003)
J. Biol. Chem. 278, 29410-29419
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Novel Role of Vitamin K in Preventing Oxidative Injury to Developing Oligodendrocytes and Neurons.

J. Li, J. C. Lin, H. Wang, J. W. Peterson, B. C. Furie, B. Furie, S. L. Booth, J. J. Volpe, and P. A. Rosenberg (2003)
J. Neurosci. 23, 5816-5826
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Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserine.

V. E. Kagan, G. G. Borisenko, B. F. Serinkan, Y. Y. Tyurina, V. A. Tyurin, J. Jiang, S. X. Liu, A. A. Shvedova, J. P. Fabisiak, W. Uthaisang, et al. (2003)
Am J Physiol Lung Cell Mol Physiol 285, L1-L17
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Diminished Heme Oxygenase Potentiates Cell Death: Pyrrolidinedithiocarbamate Mediates Oxidative Stress.

L. Malaguarnera, S. Quan, M. R. Pilastro, N. G. Abraham, and A. Kappas (2003)
Experimental Biology and Medicine 228, 459-465
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{beta}-Carotene Regulates NF-{kappa}B DNA-Binding Activity by a Redox Mechanism in Human Leukemia and Colon Adenocarcinoma Cells.

P. Palozza, S. Serini, A. Torsello, F. Di Nicuolo, E. Piccioni, V. Ubaldi, C. Pioli, F. I. Wolf, and G. Calviello (2003)
J. Nutr. 133, 381-388
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Susceptibility of Lysosomes to Rupture Is a Determinant for Plasma Membrane Disruption in Tumor Necrosis Factor Alpha-Induced Cell Death.

K. Ono, S. O. Kim, and J. Han (2003)
Mol. Cell. Biol. 23, 665-676
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Critical Roles of Thioredoxin in Nerve Growth Factor-Mediated Signal Transduction and Neurite Outgrowth in PC12 Cells.

J. Bai, H. Nakamura, Y.-W. Kwon, I. Hattori, Y. Yamaguchi, Y.-C. Kim, N. Kondo, S.-i. Oka, S. Ueda, H. Masutani, et al. (2003)
J. Neurosci. 23, 503-509
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Oxidative Stress-Induced Iron Signaling Is Responsible for Peroxide-Dependent Oxidation of Dichlorodihydrofluorescein in Endothelial Cells: Role of Transferrin Receptor-Dependent Iron Uptake in Apoptosis.

Y. Tampo, S. Kotamraju, C. R. Chitambar, S. V. Kalivendi, A. Keszler, J. Joseph, and B. Kalyanaraman (2003)
Circ. Res. 92, 56-63
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SOD2 Functions Downstream of Sch9 to Extend Longevity in Yeast.

P. Fabrizio, L.-L. Liou, V. N. Moy, A. Diaspro, J. Selverstone Valentine, E. B. Gralla, and V. D. Longo (2003)
Genetics 163, 35-46
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Effect of Bcl-2 Overexpression on Mitochondrial Structure and Function.

A. J. Kowaltowski, R. G. Cosso, C. B. Campos, and G. Fiskum (2002)
J. Biol. Chem. 277, 42802-42807
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The antiapoptotic protein Bcl-xL prevents the cytotoxic effect of Bax, but not Bax-induced formation of reactive oxygen species, in Kluyveromyces lactis.

D. Poliakova, B. Sokolikova, J. Kolarov, and L'u. Sabova (2002)
Microbiology 148, 2789-2795
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A Bax-Induced Pro-Oxidant State Is Critical for Cytochrome c Release during Programmed Neuronal Death.

R. A. Kirkland, J. A. Windelborn, J. M. Kasprzak, and J. L. Franklin (2002)
J. Neurosci. 22, 6480-6490
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Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases.

E. Werner and Z. Werb (2002)
J. Cell Biol. 158, 357-368
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Inhibition of Glutamine Synthetase in A549 Cells During Hyperoxia.

S. A. McGrath-Morrow and J. Stahl (2002)
Am. J. Respir. Cell Mol. Biol. 27, 99-106
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GD3 Recruits Reactive Oxygen Species to Induce Cell Proliferation and Apoptosis in Human Aortic Smooth Muscle Cells.

A. K. Bhunia, G. Schwarzmann, and S. Chatterjee (2002)
J. Biol. Chem. 277, 16396-16402
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Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.

A. Wyttenbach, O. Sauvageot, J. Carmichael, C. Diaz-Latoud, A.-P. Arrigo, and D. C. Rubinsztein (2002)
Hum. Mol. Genet. 11, 1137-1151
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Neuroprotective Effect of (2S,3S,4R)-N""-cyano-N-(6-amino-3, 4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378), a Benzopyran Analog, against Focal Ischemic Brain Damage in Rats.

K. W. Hong, K. Y. Kim, J. H. Lee, H. K. Shin, Y. G. Kwak, S.-O. Kim, H. Lim, and S.-E. Yoo (2002)
J. Pharmacol. Exp. Ther. 301, 210-216
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Antisense RNA Down-Regulation of bcl-xL Expression in Prostate Cancer Cells Leads to Diminished Rates of Cellular Proliferation and Resistance to Cytotoxic Chemotherapeutic Agents.

M. Vilenchik, A. J. Raffo, L. Benimetskaya, D. Shames, and C. A. Stein (2002)
Cancer Res. 62, 2175-2183
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Doxorubicin Induces Apoptosis and CD95 Gene Expression in Human Primary Endothelial Cells through a p53-dependent Mechanism.

E. Lorenzo, C. Ruiz-Ruiz, A. J. Quesada, G. Hernandez, A. Rodriguez, A. Lopez-Rivas, and J. M. Redondo (2002)
J. Biol. Chem. 277, 10883-10892
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Bcl-xl reduces doxorubicin-induced myocardial damage but fails to control cardiac gene downregulation.

K. Kunisada, E. Tone, S. Negoro, Y. Nakaoka, Y. Oshima, T. Osugi, M. Funamoto, M. Izumi, Y. Fujio, H. Hirota, et al. (2002)
Cardiovasc Res 53, 936-943
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Glutathione Dependence of Caspase-8 Activation at the Death-inducing Signaling Complex.

H. Hentze, I. Schmitz, M. Latta, A. Krueger, P. H. Krammer, and A. Wendel (2002)
J. Biol. Chem. 277, 5588-5595
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Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by {beta}-carotene through down-regulation of cyclin A and Bcl-2 family proteins.

P. Palozza, S. Serini, N. Maggiano, M. Angelini, A. Boninsegna, F. Di Nicuolo, F. O. Ranelletti, and G. Calviello (2002)
Carcinogenesis 23, 11-18
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Role of Caspase 3-Dependent Bcl-2 Cleavage in Potentiation of Apoptosis by Bcl-2.

Y. Liang, K. D. Nylander, C. Yan, and N. F. Schor (2002)
Mol. Pharmacol. 61, 142-149
 |  Abstract »  |  Full Text »  |  PDF »

Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational view.

A. D. Schimmer, D. W. Hedley, L. Z. Penn, and M. D. Minden (2001)
Blood 98, 3541-3553
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VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release.

M. Madesh and G. Hajnoczky (2001)
J. Cell Biol. 155, 1003-1016
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Effect of Glutathione Depletion on Antitumor Drug Toxicity (Apoptosis and Necrosis) in U-937 Human Promonocytic Cells. THE ROLE OF INTRACELLULAR OXIDATION.

A. Troyano, C. Fernandez, P. Sancho, E. de Blas, and P. Aller (2001)
J. Biol. Chem. 276, 47107-47115
 |  Abstract »  |  Full Text »  |  PDF »

Human bcl-2 Gene Attenuates the Ability of Rabbit Lens Epithelial Cells against H2O2-induced Apoptosis through Down-regulation of the alpha B-crystallin Gene.

Y.-W. Mao, H. Xiang, J. Wang, S. Korsmeyer, J. Reddan, and D. W.-C. Li (2001)
J. Biol. Chem. 276, 43435-43445
 |  Abstract »  |  Full Text »  |  PDF »

Serine proteases increase oxidative stress in lung cells.

K. Aoshiba, K. Yasuda, S. Yasui, J. Tamaoki, and A. Nagai (2001)
Am J Physiol Lung Cell Mol Physiol 281, L556-L564
 |  Abstract »  |  Full Text »  |  PDF »

In situ immunohistochemical study of Bcl-2 and heat shock proteins in human corneal endothelial cells during corneal storage.

P. Gain, G. Thuret, C. Chiquet, J. M. Dumollard, J. F. Mosnier, and L. Campos (2001)
Br. J. Ophthalmol. 85, 996-1000
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Tobacco smoke reduces viability in human lung fibroblasts: protective effect of glutathione S-transferase P1.

T. Ishii, T. Matsuse, H. Igarashi, M. Masuda, S. Teramoto, and Y. Ouchi (2001)
Am J Physiol Lung Cell Mol Physiol 280, L1189-L1195
 |  Abstract »  |  Full Text »  |  PDF »

Targeted Expression of bcl-2 to Murine Basal Epidermal Keratinocytes Results in Paradoxical Retardation of Ultraviolet- and Chemical-induced Tumorigenesis.

H. Rossiter, S. Beissert, C. Mayer, M. P. Schön, B. G. Wienrich, E. Tschachler, and T. S. Kupper (2001)
Cancer Res. 61, 3619-3626
 |  Abstract »  |  Full Text »

Direct binding and functional coupling of {alpha}-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

F. J. S. LEE, F. LIU, Z. B. PRISTUPA, and H. B. NIZNIK (2001)
FASEB J 15, 916-926
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Redox Regulation of Cytochrome c Release during Programmed Neuronal Death: Antioxidant Effects of Protein Synthesis and Caspase Inhibition.

R. A. Kirkland and J. L. Franklin (2001)
J. Neurosci. 21, 1949-1963
 |  Abstract »  |  Full Text »  |  PDF »

Fas (CD95)-Fas Ligand Interactions Are Responsible for Monocyte Apoptosis Occurring as a Result of Phagocytosis and Killing of Staphylococcus aureus.

J. Baran, K. Weglarczyk, M. Mysiak, K. Guzik, M. Ernst, H.-D. Flad, and J. Pryjma (2001)
Infect. Immun. 69, 1287-1297
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Interleukin 10 by Rituximab Results in Down-Regulation of Bcl-2 and Sensitization of B-cell Non-Hodgkin's Lymphoma to Apoptosis.

S. Alas, C. Emmanouilides, and B. Bonavida (2001)
Clin. Cancer Res. 7, 709-723
 |  Abstract »  |  Full Text »

Prolonged hypoxia during cell development protects mature manganese superoxide dismutase-deficient astrocytes from damage by oxidative stress.

J.-C. COPIN, Y. GASCHE, Y. LI, and P. H. CHAN (2001)
FASEB J 15, 525-534
 |  Abstract »  |  Full Text »  |  PDF »

Caspase Inhibitors Attenuate Oxyhemoglobin-Induced Apoptosis in Endothelial Cells.

T. Meguro, B. Chen, A. D. Parent, and J. H. Zhang (2001)
Stroke 32, 561-566
 |  Abstract »  |  Full Text »  |  PDF »

Caspase Activation by Adenovirus E4orf4 Protein Is Cell Line Specific and Is Mediated by the Death Receptor Pathway.

A. Livne, R. Shtrichman, and T. Kleinberger (2001)
J. Virol. 75, 789-798
 |  Abstract »  |  Full Text »

Photodynamic Therapy Using Lu-Tex Induces Apoptosis In Vitro, and Its Effect Is Potentiated by Angiostatin in Retinal Capillary Endothelial Cells.

R. Z. Renno, F. C. Delori, R. A. Holzer, E. S. Gragoudas, and J. W. Miller (2000)
Invest. Ophthalmol. Vis. Sci. 41, 3963-3971
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The Molecular Effects of Acrolein.

J. P. Kehrer and S. S. Biswal (2000)
Toxicol. Sci. 57, 6-15
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Elevation of resting mitochondrial membrane potential of neural cells by cyclosporin A, BAPTA-AM, and Bcl-2.

A. J. Kowaltowski, S. S. Smaili, J. T. Russell, and G. Fiskum (2000)
Am J Physiol Cell Physiol 279, C852-C859
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Bcl-xL Prevents the Initial Decrease in Mitochondrial Membrane Potential and Subsequent Reactive Oxygen Species Production during Tumor Necrosis Factor Alpha-Induced Apoptosis.

E. Gottlieb, M. G. Vander Heiden, and C. B. Thompson (2000)
Mol. Cell. Biol. 20, 5680-5689
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Nitric oxide induces apoptosis in the human corpus luteum in vitro.

M. Vega, L. Urrutia, G. Iniguez, F. Gabler, L. Devoto, and M.C. Johnson (2000)
Mol. Hum. Reprod. 6, 681-687
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Involvement of Mitochondria in Oxidative Stress-Induced Cell Death in Mouse Zygotes.

L. Liu, J. R. Trimarchi, and D. L. Keefe (2000)
Biol Reprod 62, 1745-1753
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Cytoplasm Mediates Both Development and Oxidation-Induced Apoptotic Cell Death in Mouse Zygotes.

L. Liu and D. L. Keefe (2000)
Biol Reprod 62, 1828-1834
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Interleukin-6-Induced Protection in Hyperoxic Acute Lung Injury.

N. S. Ward, A. B. Waxman, R. J. Homer, L. L. Mantell, O. Einarsson, Y. Du, and J. A. Elias (2000)
Am. J. Respir. Cell Mol. Biol. 22, 535-542
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Tumor Necrosis Factor-alpha Increases the Steady-state Reduction of Cytochrome b of the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells.

J. A. Sanchez-Alcazar, E. Schneider, M. A. Martinez, P. Carmona, I. Hernandez-Munoz, E. Siles, P. De la Torre, J. Ruiz-Cabello, I. Garcia, and J. A. Solis-Herruzo (2000)
J. Biol. Chem. 275, 13353-13361
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Geranylgeranyl-Pyrophosphate, an Isoprenoid of Mevalonate Cascade, Is a Critical Compound for Rat Primary Cultured Cortical Neurons to Protect the Cell Death Induced by 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibition.

T. Tanaka, I. Tatsuno, D. Uchida, I. Moroo, H. Morio, S. Nakamura, Y. Noguchi, T. Yasuda, M. Kitagawa, Y. Saito, et al. (2000)
J. Neurosci. 20, 2852-2859
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Study of apoptotic DNA fragmentation in human spermatozoa.

L. Gandini, F. Lombardo, D. Paoli, L. Caponecchia, G. Familiari, C. Verlengia, F. Dondero, and A. Lenzi (2000)
Hum. Reprod. 15, 830-839
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Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intra