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Science 17 December 1993:
Vol. 262. no. 5141, pp. 1901 - 1904
DOI: 10.1126/science.8266083
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Articles

Science, Vol 262, Issue 5141, 1901-1904
Copyright © 1993 by American Association for the Advancement of Science

articles

Linearity of summation of synaptic potentials underlying direction selectivity in simple cells of the cat visual cortex

B Jagadeesh, HS Wheat, and D Ferster

Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208.

Intracellular recordings from simple cells of the cat visual cortex were used to test linear models for the generation of selectivity for the direction of visual motion. Direction selectivity has been thought to arise in part from nonlinear processes, as suggested by previous experiments that were based on extracellular recordings of action potentials. In intracellular recordings, however, the fluctuations in membrane potential evoked by moving stimuli were accurately predicted by the linear summation of responses to stationary stimuli. Nonlinear mechanisms were not required.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)