Science 26 August 1994: Vol. 265. no. 5176, pp. 1221 - 1225 DOI: 10.1126/science.8066460

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Articles

Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity.

T. Kubota, S. Maezawa, K. Koiwai, T. Hayano, and O. Koiwai (2007)
Genes Cells 12, 941-959
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Abnormal V(D)J Recombination of T Cell Receptor {beta} Locus in SMAR1 Transgenic Mice.

R. Kaul-Ghanekar, S. Majumdar, A. Jalota, N. Gulati, N. Dubey, B. Saha, and S. Chattopadhyay (2005)
J. Biol. Chem. 280, 9450-9459
 |  Abstract »  |  Full Text »  |  PDF »

The Epigenetic Stability of the Locus Control Region-Deficient IgH Locus in Mouse Hybridoma Cells Is a Clonally Varying, Heritable Feature.

D. Ronai, M. Berru, and M. J. Shulman (2004)
Genetics 167, 411-421
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Combinatorial Control of DNase I-hypersensitive Site Formation and Erasure by Immunoglobulin Heavy Chain Enhancer-binding Proteins.

H. Ishii, R. Sen, and M. J. Pazin (2004)
J. Biol. Chem. 279, 7331-7338
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Genomic Imprinting Controls Matrix Attachment Regions in the Igf2 Gene.

M. Weber, H. Hagege, A. Murrell, C. Brunel, W. Reik, G. Cathala, and T. Forne (2003)
Mol. Cell. Biol. 23, 8953-8959
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SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin {micro} gene expression.

G. Dobreva, J. Dambacher, and R. Grosschedl (2003)
Genes & Dev. 17, 3048-3061
 |  Abstract »  |  Full Text »  |  PDF »

Lentivirus Vectors Incorporating the Immunoglobulin Heavy Chain Enhancer and Matrix Attachment Regions Provide Position-Independent Expression in B Lymphocytes.

C. Lutzko, D. Senadheera, D. Skelton, D. Petersen, and D. B. Kohn (2003)
J. Virol. 77, 7341-7351
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Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions.

S. Rampalli, A. Kulkarni, P. Kumar, D. Mogare, S. Galande, D. Mitra, and S. Chattopadhyay (2003)
Nucleic Acids Res. 31, 3248-3256
 |  Abstract »  |  Full Text »  |  PDF »

The Transcriptional Enhancer of the Pea Plastocyanin Gene Associates with the Nuclear Matrix and Regulates Gene Expression through Histone Acetylation.

Y. L. Chua, L. A. Watson, and J. C. Gray (2003)
PLANT CELL 15, 1468-1479
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Positive and Negative Transcriptional States of a Variegating Immunoglobulin Heavy Chain (IgH) Locus Are Maintained by a cis-Acting Epigenetic Mechanism.

D. Ronai, M. Berru, and M. J. Shulman (2002)
J. Immunol. 169, 6919-6927
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DNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex.

S. K. Mauldin, R. C. Getts, W. Liu, and T. D. Stamato (2002)
Nucleic Acids Res. 30, 4075-4087
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Transgene Silencing by Matrix Attachment Regions in Maize: A Dual Role for the Maize 5' ADH1 Matrix Attachment Region.

C. Brouwer, W. Bruce, S. Maddock, Z. Avramova, and B. Bowen (2002)
PLANT CELL 14, 2251-2264
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Candidate Regulatory Region in the Human CD8 Gene Complex by Colocalization of DNase I Hypersensitive Sites and Matrix Attachment Regions Which Bind SATB1 and GATA-3.

L. J. Kieffer, J. M. Greally, I. Landres, S. Nag, Y. Nakajima, T. Kohwi-Shigematsu, and P. B. Kavathas (2002)
J. Immunol. 168, 3915-3922
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Assembly of Two Transgenes in an Artificial Chromatin Domain Gives Highly Coordinated Expression in Tobacco.

L. Mlynarova, A. Loonen, E. Mietkiewska, R. C. Jansen, and J.-P. Nap (2002)
Genetics 160, 727-740
 |  Abstract »  |  Full Text »  |  PDF »

SATB1 Cleavage by Caspase 6 Disrupts PDZ Domain-Mediated Dimerization, Causing Detachment from Chromatin Early in T-Cell Apoptosis.

S. Galande, L. A. Dickinson, I. S. Mian, M. Sikorska, and T. Kohwi-Shigematsu (2001)
Mol. Cell. Biol. 21, 5591-5604
 |  Abstract »  |  Full Text »  |  PDF »

The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions.

B. M. Shewchuk, N. E. Cooke, and S. A. Liebhaber (2001)
Nucleic Acids Res. 29, 3356-3361
 |  Abstract »  |  Full Text »  |  PDF »

A Pivotal Role for DNase I-Sensitive Regions 3b and/or 4 in the Induction of Somatic Hypermutation of IgH Genes.

A. Terauchi, K. Hayashi, D. Kitamura, Y. Kozono, N. Motoyama, and T. Azuma (2001)
J. Immunol. 167, 811-820
 |  Abstract »  |  Full Text »  |  PDF »

A New Regulatory Region of the IL-2 Locus That Confers Position-Independent Transgene Expression.

M. A. Yui, G. Hernandez-Hoyos, and E. V. Rothenberg (2001)
J. Immunol. 166, 1730-1739
 |  Abstract »  |  Full Text »  |  PDF »

Matrix Attachment Region-Dependent Function of the Immunoglobulin {micro} Enhancer Involves Histone Acetylation at a Distance without Changes in Enhancer Occupancy.

L. A. Fernández, M. Winkler, and R. Grosschedl (2001)
Mol. Cell. Biol. 21, 196-208
 |  Abstract »  |  Full Text »

The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire.

K. Yu and M. R. Lieber (2000)
Mol. Cell. Biol. 20, 7914-7921
 |  Abstract »  |  Full Text »

Orchestrated response: a symphony of transcription factors for gene control.

B. Lemon and R. Tjian (2000)
Genes & Dev. 14, 2551-2569
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DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis.

P. L. Strissel, R. Strick, R. J. Tomek, B. A. Roe, J. D. Rowley, and N. J. Zeleznik-Le (2000)
Hum. Mol. Genet. 9, 1671-1679
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Rearrangement of chromatin domains during development in Xenopus.

Y. Vassetzky, A. Hair, and M. Méchali (2000)
Genes & Dev. 14, 1541-1552
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Locus control region activity by 5'HS3 requires a functional interaction with beta -globin gene regulatory elements: expression of novel beta /gamma -globin hybrid transgenes.

J. E. Rubin, P. Pasceri, X. Wu, P. Leboulch, and J. Ellis (2000)
Blood 95, 3242-3249
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Matrix Attachment Regions of Human Papillomavirus Type 16 Repress or Activate the E6 Promoter, Depending on the Physical State of the Viral DNA.

W. Stünkel, Z. Huang, S.-H. Tan, M. J. O'Connor, and H.-U. Bernard (2000)
J. Virol. 74, 2489-2501
 |  Abstract »  |  Full Text »

The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development.

J. D. Alvarez, D. H. Yasui, H. Niida, T. Joh, D. Y. Loh, and T. Kohwi-Shigematsu (2000)
Genes & Dev. 14, 521-535
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An Upstream Oct-1- and Oct-2-Binding Silencer Governs B29 (Ig{beta}) Gene Expression.

C. S. Malone, L. Patrone, K. L. Buchanan, C. F. Webb, and R. Wall (2000)
J. Immunol. 164, 2550-2556
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Conserved characteristics of heterochromatin-forming DNA at the 15q11-q13 imprinting center.

J. M. Greally, T. A. Gray, J. M. Gabriel, L. q. Song, S. Zemel, and R. D. Nicholls (1999)
PNAS 96, 14430-14435
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions.

W. C. Forrester, L. A. Fernández, and R. Grosschedl (1999)
Genes & Dev. 13, 3003-3014
 |  Abstract »  |  Full Text »

HMG-I(Y) Recognizes Base-unpairing Regions of Matrix Attachment Sequences and Its Increased Expression Is Directly Linked to Metastatic Breast Cancer Phenotype.

W.-M. Liu, F. K. Guerra-Vladusic, S. Kurakata, R. Lupu, and T. Kohwi-Shigematsu (1999)
Cancer Res. 59, 5695-5703
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Ig Heavy Chain 3' HS1-4 Directs Correct Spatial Position-Independent Expression of a Linked Transgene to B Lineage Cells.

C. Chauveau, E. A. Jansson, S. Muller, M. Cogne, and S. Pettersson (1999)
J. Immunol. 163, 4637-4641
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Epigenetics: Regulation Through Repression.

A. P. Wolffe and M. A. Matzke (1999)
Science 286, 481-486
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Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination.

X.-P. Zhong, J. Carabana, and M. S. Krangel (1999)
PNAS 96, 11970-11975
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Variegated Expression of the Endogenous Immunoglobulin Heavy-Chain Gene in the Absence of the Intronic Locus Control Region.

D. Ronai, M. Berru, and M. J. Shulman (1999)
Mol. Cell. Biol. 19, 7031-7040
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The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination.

E. Sakai, A. Bottaro, and F. W. Alt (1999)
Int. Immunol. 11, 1709-1713
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Element Upstream of the V{gamma}2 Gene in the Murine T Cell Receptor {gamma} Locus Cooperates with the 3' Enhancer to Act as a Locus Control Region.

J. E. Baker, J. Kang, N. Xiong, T. Chen, D. Cado, and D. H. Raulet (1999)
J. Exp. Med. 190, 669-680
 |  Abstract »  |  Full Text »  |  PDF »

Poly(ADP-ribose) Polymerase and Ku Autoantigen Form a Complex and Synergistically Bind to Matrix Attachment Sequences.

S. Galande and T. Kohwi-Shigematsu (1999)
J. Biol. Chem. 274, 20521-20528
 |  Abstract »  |  Full Text »  |  PDF »

Homeoproteins CDP and SATB1 Interact: Potential for Tissue-Specific Regulation.

J. Liu, A. Barnett, E. J. Neufeld, and J. P. Dudley (1999)
Mol. Cell. Biol. 19, 4918-4926
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Intronic Elements in the Endogenous Immunoglobulin Heavy Chain Locus. EITHER THE MATRIX ATTACHMENT REGIONS OR THE CORE ENHANCER IS SUFFICIENT TO MAINTAIN EXPRESSION.

E. J. Wiersma, D. Ronai, M. Berru, F. W. L. Tsui, and M. J. Shulman (1999)
J. Biol. Chem. 274, 4858-4862
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Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions.

E. Sakai, A. Bottaro, L. Davidson, B. P. Sleckman, and F. W. Alt (1999)
PNAS 96, 1526-1531
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of {micro} Enhancer Regulation in B Lymphocytes.

B.S. NIKOLAJCZYK, W. DANG, and R. SEN (1999)
Cold Spring Harb Symp Quant Biol 64, 99-108
 |  Abstract »  |  PDF »

Cux/CDP Homeoprotein Is a Component of NF-µNR and Represses the Immunoglobulin Heavy Chain Intronic Enhancer by Antagonizing the Bright Transcription Activator.

Z. Wang, A. Goldstein, R.-T. Zong, D. Lin, E. J. Neufeld, R. H. Scheuermann, and P. W. Tucker (1999)
Mol. Cell. Biol. 19, 284-295
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Immunoglobulin Gene Transcription via Nuclear Matrix-associated Regions.

C. WEBB, R.-T. ZONG, D. LIN, Z. WANG, M. KAPLAN, Y. PAULIN, E. SMITH, L. PROBST, J. BRYANT, A. GOLDSTEIN, et al. (1999)
Cold Spring Harb Symp Quant Biol 64, 109-118
 |  Abstract »  |  PDF »

Characterization of Human Endotoxin Lipopolysaccharide Receptor CD14 Expression in Transgenic Mice.

C. J. Hetherington, P. D. Kingsley, F. Crocicchio, P. Zhang, M. S. Rabin, J. Palis, and D.-E. Zhang (1999)
J. Immunol. 162, 503-509
 |  Abstract »  |  Full Text »  |  PDF »

A Nuclear Matrix Attachment Region Upstream of the T Cell Receptor beta  Gene Enhancer Binds Cux/CDP and SATB1 and Modulates Enhancer-dependent Reporter Gene Expression but Not Endogenous Gene Expression.

S. Chattopadhyay, C. E. Whitehurst, and J. Chen (1998)
J. Biol. Chem. 273, 29838-29846
 |  Abstract »  |  Full Text »  |  PDF »

Evidence that Immunoglobulin VH-DJ Recombination Does Not Require Germ Line Transcription of the Recombining Variable Gene Segment.

C. Angelin-Duclos and K. Calame (1998)
Mol. Cell. Biol. 18, 6253-6264
 |  Abstract »  |  Full Text »

Purification and Characterization of a Protein Binding to the SP6 kappa  Promoter. A POTENTIAL ROLE FOR CArG-BOX BINDING FACTOR-A IN kappa  TRANSCRIPTION.

M. Bemark, H. Olsson, D. Heinegard, and T. Leanderson (1998)
J. Biol. Chem. 273, 18881-18890
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kappa chain monoallelic demethylation and the establishment of allelic exclusion.

R. Mostoslavsky, N. Singh, A. Kirillov, R. Pelanda, H. Cedar, A. Chess, and Y. Bergman (1998)
Genes & Dev. 12, 1801-1811
 |  Abstract »  |  Full Text »

Pairing of Variable Heavy and Variable {kappa} Chains in Individual Naive and Memory B Cells.

H.-P. Brezinschek, S. J. Foster, T. Dorner, R. I. Brezinschek, and P. E. Lipsky (1998)
J. Immunol. 160, 4762-4767
 |  Abstract »  |  Full Text »  |  PDF »

The Genomic Sequences Bound to Special AT-rich Sequence-binding Protein 1 (SATB1) In Vivo in Jurkat T Cells Are Tightly Associated with the Nuclear Matrix at the Bases of the Chromatin Loops.

I. de Belle, S. Cai, and T. Kohwi-Shigematsu (1998)
J. Cell Biol. 141, 335-348
 |  Abstract »  |  Full Text »  |  PDF »

An Intronic Silencer Regulates B Lymphocyte Cell- and Stage-Specific Expression of the Human Complement Receptor Type 2 (CR2, CD21) Gene.

K. W. Makar, C. T. N. Pham, M. H. Dehoff, S. M. O'Connor, S. M. Jacobi, and V. M. Holers (1998)
J. Immunol. 160, 1268-1278
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Matrix Attachment Regions Confer Long-range Function upon the Immunoglobulin {micro} Enhancer.

L.A. FERNANDEZ, M. WINKLER, W. FORRESTER, T. JENUWEIN, and R. GROSSCHEDL (1998)
Cold Spring Harb Symp Quant Biol 63, 515-524
 |  Abstract »  |  PDF »

Conserved Enhancer Elements in Human and Mouse Renin Genes Have Different Transcriptional Effects in As4.1 Cells.

Y. Yan, C. A. Jones, C. D. Sigmund, K. W. Gross, and D. F. Catanzaro (1997)
Circ. Res. 81, 558-566
 |  Abstract »  |  Full Text »

Enhancer Complexes Located Downstream of Both Human Immunoglobulin Calpha Genes.

F. C. Mills, N. Harindranath, M. Mitchell, and E. E. Max (1997)
J. Exp. Med. 186, 845-858
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of the Nuclear Matrix-associated Region (MAR)-Binding Proteins, SATB1 and CDP/Cux, with a MAR Element (L2a) in an Upstream Regulatory Region of the Mouse CD8a Gene.

M. Banan, I. C. Rojas, W.-H. Lee, H. L. King, J. V. Harriss, R. Kobayashi, C. F. Webb, and P. D. Gottlieb (1997)
J. Biol. Chem. 272, 18440-18452
 |  Abstract »  |  Full Text »  |  PDF »

A c-erbB-2 Promoter-specific Nuclear Matrix Protein from Human Breast Tumor Tissues Mediates NF-kappa B DNA Binding Activity.

A. Raziuddin, D. Court, F. H. Sarkar, Y.-L. Liu, H.-f. Kung, and R. Raziuddin (1997)
J. Biol. Chem. 272, 15715-15720
 |  Abstract »  |  Full Text »  |  PDF »

An enhancer-blocking element between alpha  and delta  gene segments within the human T cell receptor alpha /delta  locus.

X.-P. Zhong and M. S. Krangel (1997)
PNAS 94, 5219-5224
 |  Abstract »  |  Full Text »  |  PDF »

An Atypical Homeodomain in SATB1 Promotes Specific Recognition of the Key Structural Element in a Matrix Attachment Region.

L. A. Dickinson, C. D. Dickinson, and T. Kohwi-Shigematsu (1997)
J. Biol. Chem. 272, 11463-11470
 |  Abstract »  |  Full Text »  |  PDF »

Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix.

J. C. Reyes, C. Muchardt, and M. Yaniv (1997)
J. Cell Biol. 137, 263-274
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of  T Cell Receptor delta  Gene Rearrangement by CBF/PEBP2.

P. Lauzurica, X.-P. Zhong, M. S. Krangel, and J. L. Roberts (1997)
J. Exp. Med. 185, 1193-1202
 |  Abstract »  |  Full Text »  |  PDF »

The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo..

J Zhou, S Barolo, P Szymanski, and M Levine (1996)
Genes & Dev. 10, 3195-3201
 |  Abstract »  |  PDF »

The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family..

R F Herrscher, M H Kaplan, D L Lelsz, C Das, R Scheuermann, and P W Tucker (1995)
Genes & Dev. 9, 3067-3082
 |  Abstract »  |  PDF »

Nuclear Factor Binding Sites in Human beta Globin IVS2.

C. E. Jackson, D. O' Neill, and A. Bank (1995)
J. Biol. Chem. 270, 28448-28456
 |  Abstract »  |  Full Text »  |  PDF »

Mutually Exclusive Interaction of a Novel Matrix Attachment Region Binding Protein and the NF-µNR Enhancer Repressor.

R.-T. Zong and R. H. Scheuermann (1995)
J. Biol. Chem. 270, 24010-24018
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Matrix Attachment Region DNA Binding Motif Identified Using a Random Phage Peptide Library.

B. Wang, L. A. Dickinson, E. Koivunen, E. Ruoslahti, and T. Kohwi-Shigematsu (1995)
J. Biol. Chem. 270, 23239-23242
 |  Abstract »  |  Full Text »  |  PDF »

Progressive maturation of chromatin structure regulates HSP70.1 gene expression in the preimplantation mouse embryo.

E. Thompson, E Legouy, E Christians, and J. Renard (1995)
Development 121, 3425-3437
 |  Abstract »  |  PDF »

Transcriptional Activation by a Matrix Associating Region-binding Protein. CONTEXTUAL REQUIREMENTS FOR THE FUNCTION OF BRIGHT.

M. H. Kaplan, R.-T. Zong, R. F. Herrscher, R. H. Scheuermann, and P. W. Tucker (2001)
J. Biol. Chem. 276, 21325-21330
 |  Abstract »  |  Full Text »  |  PDF »

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

Y. Zhang, P. Strissel, R. Strick, J. Chen, G. Nucifora, M. M. Le Beau, R. A. Larson, and J. D. Rowley (2002)
PNAS 99, 3070-3075
 |  Abstract »  |  Full Text »  |  PDF »

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