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Science 28 January 2005:
Vol. 307. no. 5709, pp. 584 - 586
DOI: 10.1126/science.1106561
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Reports

Interindividual Variation in Posture Allocation: Possible Role in Human Obesity

James A. Levine,* Lorraine M. Lanningham-Foster, Shelly K. McCrady, Alisa C. Krizan, Leslie R. Olson, Paul H. Kane, Michael D. Jensen, Matthew M. Clark

Obesity occurs when energy intake exceeds energy expenditure. Humans expend energy through purposeful exercise and through changes in posture and movement that are associated with the routines of daily life [called nonexercise activity thermogenesis (NEAT)]. To examine NEAT's role in obesity, we recruited 10 lean and 10 mildly obese sedentary volunteers and measured their body postures and movements every half-second for 10 days. Obese individuals were seated, on average, 2 hours longer per day than lean individuals. Posture allocation did not change when the obese individuals lost weight or when lean individuals gained weight, suggesting that it is biologically determined. If obese individuals adopted the NEAT-enhanced behaviors of their lean counterparts, they might expend an additional 350 calories (kcal) per day.

Endocrine Research Unit, Mayo Clinic, Rochester, MN 55905, USA.

* To whom correspondence should be addressed. E-mail: Jim{at}Mayo.edu

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