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Originally published in Science Express on 16 July 2009
Science 14 August 2009:
Vol. 325. no. 5942, pp. 883 - 885
DOI: 10.1126/science.1176170

Reports

Mindblind Eyes: An Absence of Spontaneous Theory of Mind in Asperger Syndrome

Atsushi Senju1,*, Victoria Southgate1, Sarah White2 and Uta Frith2,3

1 Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK.
2 Institute of Cognitive Neuroscience, University College London, London, UK.
3 Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus University Hospital, Norrebrogade 44, Building 10 G, 800 Aarhus C, Denmark.


Figure 1
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Fig. 1. Selected scenes from stimulus movies (see also movies S1 and S2). In familiarization trials, participants were familiarized to an event in which (A) the puppet placed a ball in one of two boxes, (B) both windows were illuminated and a chime sounded, and (C) an actor reached through the window above the box in which the ball was placed and retrieved the ball. The participants were familiarized to the contingency between (B) and (C). In (D), the puppet moves the ball while the actor is looking away. This operation induces a false belief in the actor about the location of the ball.

 

Figure 2
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Fig. 2. (A) Mean (± SEM) DLS (19) and (B) the ratio of the number of participants who made correct first saccades in each group. AS, participants with Asperger syndrome (n = 19); NT, neurotypical participants (n = 17). *P < 0.05; **P < 0.01. Dotted lines indicate chance level. Statistical test used: (A), t test; (B), binominal test.

 





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