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Science 27 October 1995:
Vol. 270. no. 5236, p. 557
DOI:

This Week in Science

Because of paternal inheritance, the fetus is usually not a histocompatible match to its mother. Why, then, if they are in contact, does the immune system of the mother not attack the fetus? Tafuri et al. (p. 630) show that during pregnancy, maternal T cells reactive to the father's alloantigens are tolerized. This tolerance is lost after birth, and may explain why in some cases autoimmune diseases go into remission during pregnancy.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)