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Science 27 October 1995:
Vol. 270. no. 5236, pp. 578 - 579
DOI: 10.1126/science.270.5236.578
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Research News

Wade Roush

Boston, Massachusetts--In this issue of Science (pp. 637 and 641), a team of researchers in Paris and Cambridge, Massachusetts, has provided a clue to a central mystery in developmental biology: How do two cells with identical sets of genes develop along different paths? In one species of bacteria, a protein called SpoIIE initiates a cascade of biochemical changes on only one side of a burgeoning cell membrane, causing one of the new cells to become a specialized bacterial spore. This asymmetrical process may depend on differences in the cell sizes, a phenomenon that also seems to play a role in cell specialization in other species.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)