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Science 24 November 1995:
Vol. 270. no. 5240, p. 1318
DOI: 10.1126/science.270.5240.1318
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Perspectives

Michael J. Daly, Kenneth W. Minton

The bacterium Deinococcus radiodurans can survive extremely large doses of radiation without mutagenesis. Daly and Minton suggest how this organism repairs its radiation-damaged DNA so efficiently and why such a system may have evolved.

The authors are in the Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Dynamics of Deinococcus radiodurans under Controlled Growth Conditions.
S. S. Jena, H. M. Joshi, K. P. V. Sabareesh, B. V. R. Tata, and T. S. Rao (2006)
Biophys. J. 91, 2699-2707
   Abstract »    Full Text »    PDF »
Ring-Like Nucleoids and DNA Repair through Error-Free Nonhomologous End Joining in Deinococcus radiodurans..
A. Minsky, E. Shimoni, and J. Englander (2006)
J. Bacteriol. 188, 6047-6051
   Full Text »    PDF »
DNA Toroids: Framework for DNA Repair in Deinococcus radiodurans and in Germinating Bacterial Spores.
J. Englander, E. Klein, V. Brumfeld, A. K. Sharma, A. J. Doherty, and A. Minsky (2004)
J. Bacteriol. 186, 5973-5977
   Full Text »    PDF »
Ringlike Structure of the Deinococcus radiodurans Genome: A Key to Radioresistance?.
S. Levin-Zaidman, J. Englander, E. Shimoni, A. K. Sharma, K. W. Minton, and A. Minsky (2003)
Science 299, 254-256
   Abstract »    Full Text »    PDF »
RecA Protein from the Extremely Radioresistant Bacterium Deinococcus radiodurans: Expression, Purification, and Characterization.
J.-I. Kim, A. K. Sharma, S. N. Abbott, E. A. Wood, D. W. Dwyer, A. Jambura, K. W. Minton, R. B. Inman, M. J. Daly, and M. M. Cox (2002)
J. Bacteriol. 184, 1649-1660
   Abstract »    Full Text »    PDF »
Whole-Genome Shotgun Optical Mapping of Deinococcus radiodurans.
J. Lin, R. Qi, C. Aston, J. Jing, T. S. Anantharaman, B. Mishra, O. White, M. J. Daly, K. W. Minton, J. C. Venter, et al. (1999)
Science 285, 1558-1562
   Abstract »    Full Text »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)