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Science 8 December 1995:
Vol. 270. no. 5242, p. 1568
DOI: 10.1126/science.270.5242.1568
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News

Claire O'Brien

RNA polymerase has to plow through sticky spots along a DNA strand to transcribe messenger RNA. How it does so has always been something of a mystery. As it turns out, the polymerase has one of the biggest motors around. Force measurements of the enzyme show it generates more power than even ``traditional'' motor proteins, and the measurement technique--which involves a trap known as an ``optical tweezers''--may soon allow scientists to look at interactions between the enzyme and the DNA substrate in real-time.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)