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Science 15 December 1995:
Vol. 270. no. 5243, p. 1737
DOI:

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Activated CD8+ lymphocytes from individuals infected with the human immunodeficiency virus secrete soluble factors that can suppress HIV infection. Cocchi et al. (p. 1811) developed a cellular assay system and have identified three chemokines, RANTES, MIP-1alpha, and MIP-1beta, as the major components of the suppressive factor. Replication of HIV in infected cells could be suppressed with recombinant forms of these chemokines.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)