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Science 22 December 1995:
Vol. 270. no. 5244, pp. 1919 - 1920
DOI: 10.1126/science.270.5244.1919
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Research News

Jean Marx

Researchers looking to accomplish the ultimate goal of the Human Genome Project--the complete sequencing of all 3 billion bases in the genome--now have a major new tool to help them. In an article also appearing in this issue (p. 1945), Eric Lander's team at the Whitehead Institute for Biomedical Research describes a detailed new physical map of the human genome. Not only is its coverage more complete than that of previous maps, but the landmarks used, which are called sequence-tagged sites, make it more versatile and easier to use. While not yet as detailed as sequencers want, it opens the door to genomewide sequencing.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Mutations in the CNGB3 gene encoding the {beta}-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21.
S. Kohl, B. Baumann, M. Broghammer, H. Jagle, P. Sieving, U. Kellner, R. Spegal, M. Anastasi, E. Zrenner, L. T. Sharpe, et al. (2000)
Hum. Mol. Genet. 9, 2107-2116
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Science. ISSN 0036-8075 (print), 1095-9203 (online)