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Science 4 October 1996:
Vol. 274. no. 5284, pp. 67 - 68
DOI: 10.1126/science.274.5284.67
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Perspectives

Lawrence H. Boise, Craig B. Thompson

After an immune response, the body must eliminate the excess cells generated to fight the foreign invader. Recent work indicates that this removal occurs as a result of an intricate network of regulatory processes. In their Perspective, Boise and Thompson synthesize this new evidence for the control of lymphocyte number by proteases, Bcl-2-related proteins, cytokines, and adhesion factors.

The authors are in the Gwen Knapp Center for Lupus and Immunology Research, Howard Hughes Medical Institute, Departments of Medicine and Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637-5420, USA. E-mail: cthompso{at}midway.uchicago.edu


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Science. ISSN 0036-8075 (print), 1095-9203 (online)