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Science 25 October 1996:
Vol. 274. no. 5287, pp. 534 - 536
DOI: 10.1126/science.274.5287.534
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Policy Forums

Mark D. Adams and J. Craig Venter

The authors argue that the early release of unedited, unfinished genome sequence information into the public domain, as currently done by some sequencing centers on a nightly basis, should not be a policy imposed on all laboratories involved in genome research. Such data are presented without the benefit of either peer review or the researchers' own analysis, and their early release may even subvert the peer-review process. Also, as the number of genome sequencing projects increases, the amount of raw data added to public databases would become unmanageably large. Without rigorous quality control procedures and annotation, genomic sequence data are not necessarily useful.

The authors are at The Institute for Genomic Research (TIGR), Medical Center Drive, Rockville, MD 20850, USA.

Volume 274, Number 5287, Issue of 25 October 1996, pp. 534-536
©1996 by The American Association for the Advancement of Science.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
WebWise: Navigating the Human Genome Project.
K. D. Pruitt (1997)
Genome Res. 7, 1038-1039
   Full Text »    PDF »
.
(1997)
Genome Res. 7, 952-955
   Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)