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Science 22 November 1996:
Vol. 274. no. 5291, pp. 1302 - 0
DOI: 10.1126/science.274.5291.1302
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Research News
Nigel Williams
One of the biggest puzzles of cancer is why the sufferer's immune system almost always fails to eliminate the tumor. New research published in this issue (p. 1363) suggests that at least one kind of cancer cell can kill the immune cells that attack them by prompting them to commit suicide.
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Non-Small Cell Lung Cancer-derived Soluble Mediators Enhance Apoptosis in Activated T Lymphocytes through an I{kappa}B Kinase-dependent Mechanism.
- R. K. Batra, Y. Lin, S. Sharma, M. Dohadwala, J. Luo, M. Pold, and S. M. Dubinett (2003)
Cancer Res.
63, 642-646
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- Molecular aspects of multiple myeloma.
- G Pratt (2002)
Mol. Pathol.
55, 273-283
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- Human Melanoma-Reactive CD4+ and CD8+ CTL Clones Resist Fas Ligand-Induced Apoptosis and Use Fas/Fas Ligand-Independent Mechanisms for Tumor Killing.
- L. Rivoltini, M. Radrizzani, P. Accornero, P. Squarcina, C. Chiodoni, A. Mazzocchi, C. Castelli, P. Tarsini, V. Viggiano, F. Belli, et al. (1998)
J. Immunol.
161, 1220-1230
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- T Cell-Mediated, IFN-{gamma}-Facilitated Rejection of Murine B16 Melanomas.
- W. Bohm, S. Thoma, F. Leithauser, P. Moller, R. Schirmbeck, and J. Reimann (1998)
J. Immunol.
161, 897-908
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- Expression of Fas ligand in liver metastases of human colonic adenocarcinomas.
- K. Shiraki, N. Tsuji, T. Shioda, K. J. Isselbacher, and H. Takahashi (1997)
PNAS
94, 6420-6425
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