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Science 24 October 1997:
Vol. 278. no. 5338, pp. 569 - 570
DOI: 10.1126/science.278.5338.569

News & Comment

HUMAN GENETICS:
Environment Institute Lays Plans for Gene Hunt

Jocelyn Kaiser

BETHESDA, MARYLAND--Toxicologists have found dozens of genes that they think make some individuals more susceptible to pollutants and other environmental chemicals, contributing to everything from cancer to birth defects and Parkinson's disease. Hoping to ferret out dozens more of these "environmental susceptibility" gene variants, National Institutes of Health scientists are putting together a major effort to sequence DNA from perhaps 1000 people to try to demonstrate a link between certain genes and patterns of disease, thereby making it possible to identify and protect people susceptible to environmental hazards.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Environmental Genome Project: Phase I and Beyond.
S. H. Wilson and K. Olden (2004)
Mol. Interv. 4, 147-156
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A Bold New Direction for Environmental Health Research.
K. Olden, J. Guthrie, and S. Newton (2001)
Am J Public Health 91, 1964-1967
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Genetic Polymorphism of CYP Genes, Alone or in Combination, as a Risk Modifier of Tobacco-related Cancers.
H. Bartsch, U. Nair, A. Risch, M. Rojas, H. Wikman, and K. Alexandrov (2000)
Cancer Epidemiol. Biomarkers Prev. 9, 3-28
   Abstract »    Full Text »
Genetic Polymorphisms and Risk of Breast Cancer.
S. S. Coughlin and M. Piper (1999)
Cancer Epidemiol. Biomarkers Prev. 8, 1023-1032
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Science. ISSN 0036-8075 (print), 1095-9203 (online)