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Science 21 November 1997:
Vol. 278. no. 5342, p. 1405
DOI: 10.1126/science.278.5342.1405
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Research News

MEETING BRIEFS:
Heat Shock Protein Linked to Stroke Protection

Ingrid Wickelgren

Neuroscientists have identified a molecule that could lead to a new kind of stroke therapy. As reported at the 27th annual meeting of the Society for Neuroscience in New Orleans last month, researchers found that introducing the gene for a heat shock protein--so-called because it is produced in response to increased temperatures or other stresses--into the brains of rats reduced the number of neurons that died after their blood supply was cut off. While the technical obstacles of converting the finding into a therapy for stroke are formidable, researchers say it's not impossible.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis.
E. J. de la Rosa, E. Vega-Nunez, A. V. Morales, J. Serna, E. Rubio, and F. de Pablo (1998)
PNAS 95, 9950-9955
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)