DNA REPLICATION:Bringing the Mountain to Mohammed

doi:10.1126/science.282.5393.1430

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Science 20 November 1998:
Vol. 282. no. 5393, pp. 1430 - 1431
DOI: 10.1126/science.282.5393.1430

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Perspectives

DNA REPLICATION:
Bringing the Mountain to Mohammed

Richard Losick and Lucy Shapiro

Bacteria have often been thought of as bags of proteins and nucleotides, without internal structure. But, as discussed by Losick and Shapiro in their Perspective, evidence is accumulating that bacterial proteins do have specified locations within the cell. The most recent result to support this view is presented in this issue by Lemon and Grossman, who show that the DNA replication apparatus of bacteria are confined to the center of the cell. Losick and Shapiro discuss these findings.

R. Losick is in the Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA. E-mail: losick{at}biosun.harvard.edu. L. Shapiro is in the Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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