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Science 11 December 1998:
Vol. 282. no. 5396, pp. 1999 - 2000
DOI: 10.1126/science.282.5396.1999
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Perspectives

Also see the archival list of Science's Compass: Enhanced Perspectives

MICROBIOLOGY:
Enhanced: A Welcome Mat for Leprosy and Lassa Fever

Patricia G. Spear

a-dystroglycan and its sibling, b-dystroglycan, sit on the cell surface, bridging the membrane. Inside the cell, they connect with the cytoskeleton, and outside the cell they connect with components of the extracellular matrix. In her Perspective, Spear discusses new evidence in this issue (Rambukkana et al. and Cao et al.) that these proteins are also the receptors for the agents of two very different diseases--leprosy and Lassa fever.

The author is at Northwestern University Medical School, Department of Microbiology-Immunology, Chicago, IL 60611, USA. E-mail: p-spear{at}nwu.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)