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Science 8 October 1999:
Vol. 286. no. 5438, p. 197
DOI: 10.1126/science.286.5438.197l
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Directed transport of auxin, so critical for development in plants and responses to certain environmental signals, is dependent on asymmetric localization of the transporter PIN1. Steinmann et al. (p. 316) now show that PIN1 becomes localized to specific regions of the cell membrane with the help of GNOM, a membrane-associated guanine-nucleotide exchange factor. The analysis suggests that regulated vesicle trafficking results in the useful polar localization of PIN1.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)