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Science 2 November 2001:
Vol. 294. no. 5544, pp. 1015 - 1016
DOI: 10.1126/science.1066728

Perspectives

CELL BIOLOGY:
Fusion Without SNAREs?

Suzie J. Scales, Michael F. A. Finley, Richard H. Scheller

Highly orchestrated molecular rearrangements are required for two membranes to fuse, as happens, for example, during neurotransmitter release into the synapse. In an elegant Perspective, Scales et al. discuss two studies (Schoch et al., Wang et al.) that shed new light on the protein interactions involved in membrane fusion.


S. J. Scales and R. H. Scheller are at Genentech Inc., South San Francisco, CA 94080, USA. M. F. A. Finley is in the Department of Molecular and Cellular Physiology, Stanford University Medical School, Stanford, CA 94305, USA. E-mail: sscales{at}gene.com

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Science. ISSN 0036-8075 (print), 1095-9203 (online)