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Science 2 November 2001:
Vol. 294. no. 5544, p. 985
DOI: 10.1126/science.294.5544.985
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News Focus

BIOTERRORISM:
Smallpox Vaccinations: How Much Protection Remains?

Jon Cohen

Immunity from smallpox vaccination is widely assumed to decline rapidly, and those vaccinated 30 or more years ago are now unprotected. But a handful of researchers who have examined the scientific literature, including century-old studies as well as state-of-the-art explorations of immunologic memory, believe protection may be far more durable.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)