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Science 30 November 2001:
Vol. 294. no. 5548, pp. 1862 - 1865
DOI: 10.1126/science.294.5548.1862
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Caveolae: A Once-Elusive Structure Gets Some Respect

Jean Marx

Cell biologists usually focus on proteins and the genes that encode them when trying to figure out how cells regulate their many activities. But lipids, particularly when organized in distinct membrane microdomains known as caveolae and rafts, can also play important roles, such as transporting materials into and through cells and organizing the cell's signal transduction pathways. Science takes a look at these functions and also at the ongoing controversy about how many are performed by caveolae as opposed to rafts.

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H. Kathuria, Y. X. Cao, M. I. Ramirez, and M. C. Williams (2004)
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Cell Surface Orifices of Caveolae and Localization of Caveolin to the Necks of Caveolae in Adipocytes.
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Transformation of Mammary Epithelial Cells by 3-Phosphoinositide- dependent Protein Kinase-1 Activates {beta}-Catenin and c-Myc, and Down-Regulates Caveolin-1.
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Phospholipid-Cholesterol Bilayers under Osmotic Stress.
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Rapid Actions of Steroid Receptors in Cellular Signaling Pathways.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)