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Science 17 October 2003:
Vol. 302. no. 5644, pp. 376 - 379
DOI: 10.1126/science.302.5644.376
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News Focus

HORMESIS:
Sipping From a Poisoned Chalice

Jocelyn Kaiser

People have believed since antiquity that tiny doses of toxicants can be healthful. Now hormesis, a concept once discredited in scientific circles, is making a surprising comeback.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Science, hormesis and regulation.
H Douglas (2008)
Human and Experimental Toxicology 27, 603-607
   Abstract »    PDF »
A case for deliberation in response to hormesis research.
K. Elliott (2008)
Human and Experimental Toxicology 27, 529-538
   Abstract »    PDF »
U-shaped Dose Response in Vasomotor Tone: A Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics.
O.-N. Bae, K.-M. Lim, J.-Y. Han, B.-I. Jung, J.-Y. Lee, J.-Y. Noh, S.-M. Chung, M.-Y. Lee, J.-Y. Lee, and J.-H. Chung (2008)
Toxicol. Sci. 103, 181-190
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Hormesis and toxic torts.
G. E Marchant (2008)
Human and Experimental Toxicology 27, 97-107
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Reproductive stimulation by low doses of xenoestrogens contrasts with the view of hormesis as an adaptive response.
L. Weltje, F. S vom Saal, and J. Oehlmann (2005)
Human and Experimental Toxicology 24, 431-437
   Abstract »    PDF »
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS UBIQUINONES AS THERAPIES AND EXPERIMENTAL TOOLS.
A. M. James, H. M. Cocheme, R. A. J. Smith, and M. P. Murphy (2005)
J. Biol. Chem. 280, 21295-21312
   Abstract »    Full Text »    PDF »
Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress.
L. Qin, M. L. Block, Y. Liu, R. J. Bienstock, Z. Pei, W. Zhang, X. Wu, B. Wilson, T. Burka, and J.-S. Hong (2005)
FASEB J 19, 550-557
   Abstract »    Full Text »    PDF »
Hormesis, the precautionary principle, and legal regulation.
L. M Ellman and C. R Sunstein (2004)
Human and Experimental Toxicology 23, 601-611
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)