IMMUNOLOGY: How Frustration Leads to Inflammation

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Science 2 May 2008:
Vol. 320. no. 5876, pp. 619 - 620
DOI: 10.1126/science.1158398

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Luke A. J. O'Neill

A molecular basis for asbestos-induced inflammation may lie in a particular component of the inflammasome protein complex.

School of Biochemistry and Immunology, Trinity College, Dublin, Ireland. E-mail: laoneill{at}tcd.ie

REPORTS Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica: Catherine Dostert, Virginie Pétrilli, Robin Van Bruggen, Chad Steele, Brooke T. Mossman, and Jürg Tschopp (2 May 2008)
Science 320 (5876), 674. [DOI: 10.1126/science.1156995]
| Abstract » | Full Text » | PDF » | Supporting Online Material »

EDITORS' CHOICE
Inflammasomes
A Sense of Danger in the Air: Stephen J. Simpson (6 May 2008)
Sci. Signal. 1 (18), ec169. [DOI: 10.1126/stke.118ec169]
| Abstract »

Science. ISSN 0036-8075 (print), 1095-9203 (online)

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