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Resistance genes are widely used to control plant diseases caused by bacteria, fungi, viruses, and nematodes. A single gene, Pto, encoding a protein kinase, confers resistance in tomato to the bacterial pathogen Pseudomonas syringae pv. tomato, as shown by the healthy leaves from genetically modified plants (diseased leaves are from susceptible, wild-type plants). The presence of Pto homologs in many crop species may expedite the isolation of other plant resistance genes. See page 1432. [Photo: Gregory B. Martin]


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Science. ISSN 0036-8075 (print), 1095-9203 (online)