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About the Cover


Sites of production and storage of human immunodeficiency virus (HIV) in lymphoid tissue, reconstructed in three dimensions from images of HIV RNA in 66 tissue sections. Red-colored infected cells surround, or are enmeshed, in a yellowish cloud representing viral particles associated with follicular dendritic cells. See page 985. [Image reconstruction: Gerald Sedgewick, Zhi-Qiang Zhang, Nam Pham, Biomedical Image Processing Laboratory, University of Minnesota]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)