The Dynamic Synapse

Neuroscience: A Vibrant Connection

Peter Stern
Science 25 October 2002: 769.
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Viewpoints

Neural and Immunological Synaptic Relations

Michael L. Dustin and David R. Colman
Science 25 October 2002: 785-789.
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Alzheimer's Disease Is a Synaptic Failure

Dennis J. Selkoe
Science 25 October 2002: 789-791.
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Reviews

The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits

Susana Cohen-Cory
Science 25 October 2002: 770-776.
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Postsynaptic Signaling and Plasticity Mechanisms

Morgan Sheng and Myung Jong Kim
Science 25 October 2002: 776-780.
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Emerging Roles of Presynaptic Proteins in Ca⁺⁺-Triggered Exocytosis

Jens Rettig and Erwin Neher
Science 25 October 2002: 781-785.
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This Week in Science

Editor summaries of this week's papers.
Science 25 October 2002: 699.
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Editorial:
Advice Without Dissent

David Michaels, Eula Bingham, Les Boden, Richard Clapp, Lynn R. Goldman, Polly Hoppin, Sheldon Krimsky, Celeste Monforton, David Ozonoff, and Anthony Robbins
Science 25 October 2002: 703.
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Editors' Choice

Highlights of the recent literature.
Science 25 October 2002: 705.
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NetWatch

Best of the Web in science.
Science 25 October 2002: 709.
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 AAAS News & Notes

Science 25 October 2002: 855-857.

 NEW PRODUCTS

Science 25 October 2002: 859-860.

News of the Week

HIGH-ENERGY PHYSICS:
Wayward Particles Collide With Physicists' Expectations

Charles Seife
Science 25 October 2002: 718-719.
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NATIONAL SCIENCE FOUNDATION:
White House Concerns Block Doubling Bill

Jeffrey Mervis
Science 25 October 2002: 719.
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EVOLUTIONARY GENETICS:
Jumbled DNA Separates Chimps and Humans

Elizabeth Pennisi
Science 25 October 2002: 719-721.
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PROTECTING HUMAN SUBJECTS:
Koski Steps Down After Bumpy Ride

Jocelyn Kaiser
Science 25 October 2002: 721-722.
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SEISMOLOGY:
Suit Ties Whale Deaths to Research Cruise

David Malakoff
Science 25 October 2002: 722-723.
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ENDOCRINOLOGY:
Divorcing Estrogen's Bright and Dark Sides

Greg Miller
Science 25 October 2002: 723-724.
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PALEONTOLOGY:
Cuts at Dino Monument Anger Researchers

Erik Stokstad
Science 25 October 2002: 724.
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EUROPEAN RESEARCH:
Directive Could Give Postdocs Permanency

Kirstie Urquhart
Science 25 October 2002: 724.
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LOW-DOSE RADIATION:
U.N. Faces Tough Sell on Chornobyl Research

Paul Webster
Science 25 October 2002: 725.
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PUBLIC HEALTH:
Creeping Consensus on SV40 and Polio Vaccine

Dan Ferber
Science 25 October 2002: 725-727.
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ATTOPHYSICS:
X-ray Flashes Provide Peek Into Atom Core

Adrian Cho
Science 25 October 2002: 727.
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ScienceScope

Science 25 October 2002: 721.
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Random Samples

Science 25 October 2002: 739.
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News Focus

BACTERIOPHAGE THERAPY:
Stalin's Forgotten Cure

Richard Stone
Science 25 October 2002: 728-731.
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BACTERIOPHAGE THERAPY:
Food and Agriculture: Testing Grounds for Phage Therapy

Richard Stone
Science 25 October 2002: 730.
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TOXICOLOGY:
Overhaul of CDC Panel Revives Lead Safety Debate

Dan Ferber
Science 25 October 2002: 732.
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INDIA:
Missing Generation Leaves Hole in Fabric of Research

Pallava Bagla
Science 25 October 2002: 733-735.
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THE INSTITUTE FOR GENOMIC RESEARCH MEETING:
Gene Researchers Hunt Bargains, Fixer-Uppers

Elizabeth Pennisi
Science 25 October 2002: 735-736.
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BIOINFORMATICS:
The Human Genome in 3D, at Your Fingertips

John Bohannon
Science 25 October 2002: 737.
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Letters

This Week's Letters

Science 25 October 2002: 747.
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 Reforming Undergrad Biology Curriculum

Stephen M. Smith; and Howard M. Lenhoff
Science 25 October 2002: 747.
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 Discussing the Origin of Life

Warren Borgeson;, Nathaniel A. Matlin;, Günter Wächtershäuser;, Antonio Lazcano, and Jeffrey L. Bada
Science 25 October 2002: 747-749.
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 Another Form of Bias in Conservation Research

John N. Klironomos;, J. Alan Clark, and Robert M. May
Science 25 October 2002: 749-750.
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 Revisiting an Archean Impact Layer

Bruce M. Simonson, Scott W. Hassler;, Gary R. Byerly, and Donald R. Lowe
Science 25 October 2002: 750-751.
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 CORRECTIONS AND CLARIFICATIONS

Science 25 October 2002: 751.
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Books et al.

MUSEUMS:
Whither the Museum?

Jeremy A. Sabloff
Science 25 October 2002: 755-756.
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NATURAL HISTORY:
New Life for Dead Things (in Jars)

L. Sian Gramates
Science 25 October 2002: 756.
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HISTORY OF SCIENCE:
A Scientific Rhetoric

Leah Ceccarelli
Science 25 October 2002: 757.
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 Books Received

Science 25 October 2002: 757.

Essays on Science and Society

 EPPENDORF & SCIENCE PRIZE:
ESSAYS ON SCIENCE AND SOCIETY: Making a Bigger Brain by Regulating Cell Cycle Exit

Anjen Chenn
Science 25 October 2002: 766-767.
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 ESSAYS ON SCIENCE AND SOCIETY:
2002 Grand Prize Winner

Science 25 October 2002: 767.
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Policy Forum

PUBLIC HEALTH:
National Security and the Biological Research Community

Ronald M. Atlas
Science 25 October 2002: 753-754.
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Perspectives

DENSITY FUNCTIONAL THEORY:
In Pursuit of the "Divine" Functional

Ann E. Mattsson
Science 25 October 2002: 759-760.
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QUANTUM MECHANICS:
To Condense or Not to Condense

T. M. Rice
Science 25 October 2002: 760-761.
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CANCER BIOLOGY:
Enhanced: A Matter of Dosage

Riccardo Fodde and Ron Smits
Science 25 October 2002: 761-763.
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SYSTEMS BIOLOGY:
Life's Complexity Pyramid

Zoltán N. Oltvai and Albert-László Barabási
Science 25 October 2002: 763-764.
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ARCHAEOLOGY:
Climate and Human Migrations

Tom D. Dillehay
Science 25 October 2002: 764-765.
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Brevia

 PCR in a Rayleigh-Bénard Convection Cell

Madhavi Krishnan, Victor M. Ugaz, and Mark A. Burns
Science 25 October 2002: 793.
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Research Articles

Global Air Pollution Crossroads over the Mediterranean

J. Lelieveld, H. Berresheim, S. Borrmann, P. J. Crutzen, F. J. Dentener, H. Fischer, J. Feichter, P. J. Flatau, J. Heland, R. Holzinger, R. Korrmann, M. G. Lawrence, Z. Levin, K. M. Markowicz, N. Mihalopoulos, A. Minikin, V. Ramanathan, M. de Reus, G. J. Roelofs, H. A. Scheeren, J. Sciare, H. Schlager, M. Schultz, P. Siegmund, B. Steil, E. G. Stephanou, P. Stier, M. Traub, C. Warneke, J. Williams, and H. Ziereis
Science 25 October 2002: 794-799.
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Transcriptional Regulatory Networks in Saccharomyces cerevisiae

Tong Ihn Lee, Nicola J. Rinaldi, François Robert, Duncan T. Odom, Ziv Bar-Joseph, Georg K. Gerber, Nancy M. Hannett, Christopher T. Harbison, Craig M. Thompson, Itamar Simon, Julia Zeitlinger, Ezra G. Jennings, Heather L. Murray, D. Benjamin Gordon, Bing Ren, John J. Wyrick, Jean-Bosco Tagne, Thomas L. Volkert, Ernest Fraenkel, David K. Gifford, and Richard A. Young
Science 25 October 2002: 799-804.
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Reports

Direct Observation of Percolation in a Manganite Thin Film

Liuwan Zhang, Casey Israel, Amlan Biswas, R. L. Greene, and Alex de Lozanne
Science 25 October 2002: 805-807.
Published online 19 September 2002 [DOI: 10.1126/science.1077346] (in Science Express Reports)
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Ideal Pure Shear Strength of Aluminum and Copper

Shigenobu Ogata, Ju Li, and Sidney Yip
Science 25 October 2002: 807-811.
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The Effect of Size-Dependent Nanoparticle Energetics on Catalyst Sintering

Charles T. Campbell, Stephen C. Parker, and David E. Starr
Science 25 October 2002: 811-814.
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Heterogeneous Atmospheric Aerosol Production by Acid-Catalyzed Particle-Phase Reactions

Myoseon Jang, Nadine M. Czoschke, Sangdon Lee, and Richard M. Kamens
Science 25 October 2002: 814-817.
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Robotic Observations of Dust Storm Enhancement of Carbon Biomass in the North Pacific

James K. B. Bishop, Russ E. Davis, and Jeffrey T. Sherman
Science 25 October 2002: 817-821.
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Human Occupations and Climate Change in the Puna de Atacama, Chile

Lautaro Núñez, Martin Grosjean, and Isabel Cartajena
Science 25 October 2002: 821-824.
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Network Motifs: Simple Building Blocks of Complex Networks

R. Milo, S. Shen-Orr, S. Itzkovitz, N. Kashtan, D. Chklovskii, and U. Alon
Science 25 October 2002: 824-827.
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Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3

Pascal te Welscher, Aimée Zuniga, Sanne Kuijper, Thijs Drenth, Hans J. Goedemans, Frits Meijlink, and Rolf Zeller
Science 25 October 2002: 827-830.
Published online 5 September 2002 [DOI: 10.1126/science.1075620] (in Science Express Reports)
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Timing Requirements for Insulin/IGF-1 Signaling in C. elegans

Andrew Dillin, Douglas K. Crawford, and Cynthia Kenyon
Science 25 October 2002: 830-834.
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Targeting of Cyclic AMP Degradation to ₂-Adrenergic Receptors by -Arrestins

Stephen J. Perry, George S. Baillie, Trudy A. Kohout, Ian McPhee, Maria M. Magiera, Kok Long Ang, William E. Miller, Alison J. McLean, Marco Conti, Miles D. Houslay, and Robert J. Lefkowitz
Science 25 October 2002: 834-836.
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Role of Toxoplasma gondii Myosin A in Powering Parasite Gliding and Host Cell Invasion

Markus Meissner, Dirk Schlüter, and Dominique Soldati
Science 25 October 2002: 837-840.
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Oscillatory Expression of the bHLH Factor Hes1 Regulated by a Negative Feedback Loop

Hiromi Hirata, Shigeki Yoshiura, Toshiyuki Ohtsuka, Yasumasa Bessho, Takahiro Harada, Kenichi Yoshikawa, and Ryoichiro Kageyama
Science 25 October 2002: 840-843.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reversal of Bone Loss in Mice by Nongenotropic Signaling of Sex Steroids

S. Kousteni, J.-R. Chen, T. Bellido, L. Han, A. A. Ali, C. A. O'Brien, L. Plotkin, Q. Fu, A. T. Mancino, Y. Wen, A. M. Vertino, C. C. Powers, S. A. Stewart, R. Ebert, A. M. Parfitt, R. S. Weinstein, R. L. Jilka, and S. C. Manolagas
Science 25 October 2002: 843-846.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions

Michelle Aarts, Yitao Liu, Lidong Liu, Shintaro Besshoh, Mark Arundine, James W. Gurd, Yu-Tian Wang, Michael W. Salter, and Michael Tymianski
Science 25 October 2002: 846-850.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

Mark E. Dudley, John R. Wunderlich, Paul F. Robbins, James C. Yang, Patrick Hwu, Douglas J. Schwartzentruber, Suzanne L. Topalian, Richard Sherry, Nicholas P. Restifo, Amy M. Hubicki, Michael R. Robinson, Mark Raffeld, Paul Duray, Claudia A. Seipp, Linda Rogers-Freezer, Kathleen E. Morton, Sharon A. Mavroukakis, Donald E. White, and Steven A. Rosenberg
Science 25 October 2002: 850-854.
Published online 19 September 2002 [DOI: 10.1126/science.1076514] (in Science Express Reports)
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