This Week in Science

Editor summaries of this week's papers.
Science 17 October 2003: 353.
|Full Text »

Editorial:
Agriculture and the Developing World

Donald Kennedy
Science 17 October 2003: 357.
Summary »|   PDF »|  

Editors' Choice

Highlights of the recent literature.
Science 17 October 2003: 359.
|Full Text »

NetWatch

Best of the Web in science.
Science 17 October 2003: 367.
|Full Text »

 NEW PRODUCTS

Science 17 October 2003: 465.

News of the Week

BIODEFENSE:
Researchers Await Government Response to Self-Regulation Plea

David Malakoff and Martin Enserink
Science 17 October 2003: 368.
Summary »|   Full Text »|   PDF »|  

BIOMEDICAL RESEARCH:
Spain Offers Helping Hand to Hospital Researchers

Xavier Bosch
Science 17 October 2003: 369.
Summary »|   Full Text »|   PDF »|  

STEM CELLS:
'Stemness' Genes Still Elusive

Gretchen Vogel
Science 17 October 2003: 371.
Summary »|   Full Text »|   PDF »|  

EVOLUTIONARY BIOLOGY:
Outside Agitators Alter Wasp Behavior

Elizabeth Pennisi
Science 17 October 2003: 372.
Summary »|   Full Text »|   PDF »|  

AGING RESEARCH:
Is Long Life in the Blood?

Jennifer Couzin
Science 17 October 2003: 373-375.
Summary »|   Full Text »|   PDF »|  

GEOSCIENCES:
A Call for Telling Better Time Over the Eons

Richard A. Kerr
Science 17 October 2003: 375.
Summary »|   Full Text »|   PDF »|  

ScienceScope

Science 17 October 2003: 371.
|Full Text »

Random Samples

Science 17 October 2003: 387.
|Full Text »

News Focus

HORMESIS:
Sipping From a Poisoned Chalice

Jocelyn Kaiser
Science 17 October 2003: 376-379.
Summary »|   Full Text »|   PDF »|  

HORMESIS:
A Healthful Dab of Radiation?

Jocelyn Kaiser
Science 17 October 2003: 378.
Summary »|   Full Text »|   PDF »|  

NUCLEAR PHYSICS:
Proton Guns Set Their Sights on Taming Radioactive Wastes

Dennis Normile
Science 17 October 2003: 379-381.
Summary »|   Full Text »|   PDF »|  

2003 NOBEL PRIZES:
Physicists Honored for Their Medical Insights

Gretchen Vogel
Science 17 October 2003: 382-383.
Summary »|   Full Text »|   PDF »|  

2003 NOBEL PRIZES:
Gateways Into Cells Usher in Nobels

Greg Miller
Science 17 October 2003: 383-384.
Summary »|   Full Text »|   PDF »|  

2003 NOBEL PRIZES:
Cool Theories Garner Super Kudos

Charles Seife
Science 17 October 2003: 384-385.
Summary »|   Full Text »|   PDF »|  

2003 NOBEL PRIZES:
Clearer Forecasts for the Dismal Science

Charles Seife
Science 17 October 2003: 385.
Summary »|   Full Text »|   PDF »|  

Letters

This Week's Letters

Science 17 October 2003: 391.
Summary »|   PDF »|  

 The Threat to Cone Snails

Eric Chivian, Callum M. Roberts, and Aaron S. Bernstein
Science 17 October 2003: 391.
Full Text »|   PDF »|  

 Coral Reef Decline in the Caribbean

Robert W. Buddemeier, John R. Ware;, Toby A. Gardner, Isabelle M. Côté, Jennifer A. Gill, Alastair Grant, and Andrew R. Watkinson
Science 17 October 2003: 391-393.
Full Text »|   PDF »|  

 CORRECTIONS AND CLARIFICATIONS

Science 17 October 2003: 393.
Full Text »|   PDF »|  

Books et al.

GENETICS:
King Corn

James F. Crow
Science 17 October 2003: 394-395.
Summary »|   Full Text »|   PDF »|  

ECOLOGY:
New Buzz on the Humble-Bee

Bernd Heinrich
Science 17 October 2003: 395-396.
Summary »|   Full Text »|   PDF »|  

GENOMICS:
Nota Bene: Where the Medium Is (Literally) the Message

Barbara R. Jasny
Science 17 October 2003: 396.
Summary »|   Full Text »|   PDF »|  

 Books Received

Science 17 October 2003: 396.

Policy Forum

PUBLIC HEALTH:
Enhanced: Grand Challenges in Global Health

H. Varmus, R. Klausner, E. Zerhouni, T. Acharya, A. S. Daar, and P. A. Singer
Science 17 October 2003: 398-399.
Summary »|   Full Text »|   PDF »|   Supporting Online Material »|  

Perspectives

MEDICINE:
Gene Therapy--New Challenges Ahead

David A. Williams and Christopher Baum
Science 17 October 2003: 400-401.
Summary »|   Full Text »|   PDF »|  

PLANT SCIENCES:
Will GM Rapeseed Cut the Mustard?

John Heritage
Science 17 October 2003: 401-403.
Summary »|   Full Text »|   PDF »|  

PLANETARY SCIENCE:
The Glitter of Distant Seas

Ralph Lorenz
Science 17 October 2003: 403-404.
Published online 2 October 2003 [DOI: 10.1126/science.1090464] (in Science Express Perspectives)
Summary »|   Full Text »|   PDF »|  

CLIMATE CHANGE:
Climate in Medieval Time

Raymond S. Bradley, Malcolm K. Hughes, and Henry F. Diaz
Science 17 October 2003: 404-405.
Summary »|   Full Text »|   PDF »|   Supporting Online Material »|  

MEDICINE:
PPARs as Therapeutic Targets: Reverse Cardiology?

Jorge Plutzky
Science 17 October 2003: 406-407.
Summary »|   Full Text »|   PDF »|  

Review

Seeing More Clearly: Recent Advances in Understanding Retinal Circuitry

Shigang He, Wei Dong, Qiudong Deng, Shijun Weng, and Wenzhi Sun
Science 17 October 2003: 408-411.
Abstract »|   Full Text »|   PDF »|  

Brevia

 Scanning Human Gene Deserts for Long-Range Enhancers

Marcelo A. Nobrega, Ivan Ovcharenko, Veena Afzal, and Edward M. Rubin
Science 17 October 2003: 413.
Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

LMO2-Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

S. Hacein-Bey-Abina, C. Von Kalle, M. Schmidt, M. P. McCormack, N. Wulffraat, P. Leboulch, A. Lim, C. S. Osborne, R. Pawliuk, E. Morillon, R. Sorensen, A. Forster, P. Fraser, J. I. Cohen, G. de Saint Basile, I. Alexander, U. Wintergerst, T. Frebourg, A. Aurias, D. Stoppa-Lyonnet, S. Romana, I. Radford-Weiss, F. Gross, F. Valensi, E. Delabesse, E. Macintyre, F. Sigaux, J. Soulier, L. E. Leiva, M. Wissler, C. Prinz, T. H. Rabbitts, F. Le Deist, A. Fischer, and M. Cavazzana-Calvo
Science 17 October 2003: 415-419.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

A Hybridization Model for the Plasmon Response of Complex Nanostructures

E. Prodan, C. Radloff, N. J. Halas, and P. Nordlander
Science 17 October 2003: 419-422.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Solvent-Free Electrolytes with Aqueous Solution-Like Conductivities

Wu Xu and C. Austen Angell
Science 17 October 2003: 422-425.
Abstract »|   Full Text »|   PDF »|  

Bonding Changes in Compressed Superhard Graphite

Wendy L. Mao, Ho-kwang Mao, Peter J. Eng, Thomas P. Trainor, Matthew Newville, Chi-chang Kao, Dion L. Heinz, Jinfu Shu, Yue Meng, and Russell J. Hemley
Science 17 October 2003: 425-427.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Always Good Turing: Asymptotically Optimal Probability Estimation

Alon Orlitsky, Narayana P. Santhanam, and Junan Zhang
Science 17 October 2003: 427-431.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Radar Evidence for Liquid Surfaces on Titan

Donald B. Campbell, Gregory J. Black, Lynn M. Carter, and Steven J. Ostro
Science 17 October 2003: 431-434.
Published online 2 October 2003 [DOI: 10.1126/science.1088969] (in Science Express Reports)
Abstract »|   Full Text »|   PDF »|  

Contribution of the Patagonia Icefields of South America to Sea Level Rise

Eric Rignot, Andrés Rivera, and Gino Casassa
Science 17 October 2003: 434-437.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

The Chemistry of Sexual Deception in an Orchid-Wasp Pollination System

Florian P. Schiestl, Rod Peakall, Jim G. Mant, Fernando Ibarra, Claudia Schulz, Stephan Franke, and Wittko Francke
Science 17 October 2003: 437-438.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Requirement of Mammalian Timeless for Circadian Rhythmicity

Jessica W. Barnes, Shelley A. Tischkau, Jeffrey A. Barnes, Jennifer W. Mitchell, Penny W. Burgoon, Jason R. Hickok, and Martha U. Gillette
Science 17 October 2003: 439-442.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking

Maxime Dahan, Sabine Lévi, Camilla Luccardini, Philippe Rostaing, Béatrice Riveau, and Antoine Triller
Science 17 October 2003: 442-445.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

Yi Gu, Marie-Dominique Filippi, Jose A. Cancelas, Jamie E. Siefring, Emily P. Williams, Aparna C. Jasti, Chad E. Harris, Andrew W. Lee, Rethinasamy Prabhakar, Simon J. Atkinson, David J. Kwiatkowski, and David A. Williams
Science 17 October 2003: 445-449.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

A Bayesian Networks Approach for Predicting Protein-Protein Interactions from Genomic Data

Ronald Jansen, Haiyuan Yu, Dov Greenbaum, Yuval Kluger, Nevan J. Krogan, Sambath Chung, Andrew Emili, Michael Snyder, Jack F. Greenblatt, and Mark Gerstein
Science 17 October 2003: 449-453.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPAR

Chih-Hao Lee, Ajay Chawla, Ned Urbiztondo, Debbie Liao, William A. Boisvert, and Ronald M. Evans
Science 17 October 2003: 453-457.
Published online 11 September 2003 [DOI: 10.1126/science.1087344] (in Science Express Reports)
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Hybridization Between Brassica napus and B. rapa on a National Scale in the United Kingdom

Mike J. Wilkinson, Luisa J. Elliott, Joël Allainguillaume, Michael W. Shaw, Carol Norris, Ruth Welters, Matthew Alexander, Jeremy Sweet, and David C. Mason
Science 17 October 2003: 457-459.
Published online 9 October 2003 [DOI: 10.1126/science.1088200] (in Science Express Reports)
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

Marita J. Walmsley, Steen K. T. Ooi, Lucinda F. Reynolds, Susan Harless Smith, Sandra Ruf, Anne Mathiot, Lesley Vanes, David A. Williams, Michael P. Cancro, and Victor L. J. Tybulewicz
Science 17 October 2003: 459-462.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Listeria Intracellular Growth and Virulence Require Host-Derived Lipoic Acid

Mary O'Riordan, Marlena A. Moors, and Daniel A. Portnoy
Science 17 October 2003: 462-464.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

 Comment on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (I)

Nicolas O. Fortunel, Hasan H. Otu, Huck-Hui Ng, Jinhui Chen, Xiuqian Mu, Timothy Chevassut, Xiaoyu Li, Marie Joseph, Charles Bailey, Jacques A. Hatzfeld, Antoinette Hatzfeld, Fatih Usta, Vinsensius B. Vega, Philip M. Long, Towia A. Libermann, and Bing Lim
Science 17 October 2003: 393.
Full Text »|   PDF »|  

 Comment on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (II)

Alexei V. Evsikov and Davor Solter
Science 17 October 2003: 393.
Full Text »|   PDF »|  

 Response to Comments on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature"

Natalia B. Ivanova, John T. Dimos, Christoph Schaniel, Jason A. Hackney, Kateri A. Moore, Miguel Ramalho-Santos, Soonsang Yoon, Yumi Matsuzaki, Richard C. Mulligan, Douglas A. Melton, and Ihor R. Lemischka
Science 17 October 2003: 393.
Full Text »|   PDF »|