This Week in Science

Editor summaries of this week's papers.
Science 28 October 2005: 585.
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Editorial:
Chess Game at the FDA

Donald Kennedy
Science 28 October 2005: 589.
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Editors' Choice

Highlights of the recent literature.
Science 28 October 2005: 591.
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NetWatch

Best of the Web in science.
Science 28 October 2005: 597.
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New Products

Science 28 October 2005: 687.
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News of the Week

SCIENTIFIC COMMUNITY:
'Security Breach' Leaks NIH Grant Applications Onto Web

David Grimm
Science 28 October 2005: 598.
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ASTRONOMY:
Science Takes Back Seat as Hubble Shoots the Moon

Andrew Lawler
Science 28 October 2005: 599.
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GENOMICS:
New Haplotype Map May Overhaul Gene Hunting

Jennifer Couzin
Science 28 October 2005: 601.
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NEUROSCIENCE:
Does Brain Cell Growth Drive Weight Loss?

Gretchen Vogel
Science 28 October 2005: 602.
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SCIENCE POLICY:
French Agency Cited for Lack of Women

Barbara Casassus
Science 28 October 2005: 602.
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MEDICINE:
Fused Genes May Help Explain the Origins of Prostate Cancer

Jean Marx
Science 28 October 2005: 603.
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EUROPEAN SCIENCE:
Aggrieved Turkish Scientists Welcome an E.U. Review

Gretchen Vogel
Science 28 October 2005: 605.
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ScienceScope

Science 28 October 2005: 601.
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Random Samples

Science 28 October 2005: 616.
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News Focus

U.S. WORKFORCE:
A Glass Ceiling for Asian Scientists?

Jeffrey Mervis
Science 28 October 2005: 606-607.
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PROFILE:
South Africa's Bone Man: 80 and Still Digging Into the Past

Robert Koenig
Science 28 October 2005: 608-609.
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ANTARCTIC DRILLING:
The Plan to Unlock Lake Vostok

Mason Inman
Science 28 October 2005: 611-612.
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ARCHAEOLOGY:
'Deviant' Burials Reveal Death on the Fringe in Ancient Societies

Michael Balter
Science 28 October 2005: 613.
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ASTRONOMY:
Astronomers Sweep Space for the Sources of Cosmic Dust

Robert Irion
Science 28 October 2005: 614-615.
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Letters

This Week's Letters

Science 28 October 2005: 619.
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 A Plea to Save the Voyager Mission

Louis Friedman
Science 28 October 2005: 619.
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 Revisiting the Grand Canyon

John T. Longino
Science 28 October 2005: 619.
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 Déjà Vu All Over Again for Nuclear Power?

Eugene A. Rosa
Science 28 October 2005: 619.
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 Issues Surrounding Nuclear Power

John R. Coulter
Science 28 October 2005: 619-620.
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 The Benefits of Solar Thermal Energy

Reuel Shinnar
Science 28 October 2005: 620.
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 A "Chick-a-dee" or a "Co-qui"?

Scott F. Michael;, Christopher N. Templeton, and Erick Greene
Science 28 October 2005: 620-621.
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 Regulating Commercial Cloning of Animals

Duane C. Kraemer and David Longtin
Science 28 October 2005: 621.
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 Density Is Only Relative

Stacy Daniels
Science 28 October 2005: 621.
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Books et al.

ECOLOGY:
Learning from the Aliens

Michael J. Crawley
Science 28 October 2005: 623-624.
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 Browsings

Science 28 October 2005: 624.
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Books Received

Science 28 October 2005: 624.
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Policy Forum

POLICY:
OPV Cessation--the Final Step To a "Polio-Free" World

R. Bruce Aylward, Roland W. Sutter, and David L. Heymann
Science 28 October 2005: 625-626.
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Perspectives

ATMOSPHERIC SCIENCE:
Tipping Points in the Tundra

Jonathan A. Foley
Science 28 October 2005: 627-628.
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VIROLOGY:
What Links Bats to Emerging Infectious Diseases?

Andrew P. Dobson
Science 28 October 2005: 628-629.
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DEVELOPMENTAL BIOLOGY:
Enhanced: Less Steroids Make Bigger Flies

Kirst King-Jones and Carl S. Thummel
Science 28 October 2005: 630-631.
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PHYSICS:
The Observation of Matter Wave Fluctuations

Peter L. Knight
Science 28 October 2005: 631-632.
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RETROSPECTIVE:
Joseph Rotblat (1908-2005)

John P. Holdren
Science 28 October 2005: 633.
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Association Affairs

AAAS News and Notes

Science 28 October 2005: 634-637.
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Review

Progress in Modeling of Protein Structures and Interactions

Ora Schueler-Furman, Chu Wang, Phil Bradley, Kira Misura, and David Baker
Science 28 October 2005: 638-642.
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Brevia

The Asian Tsunami: A Protective Role for Coastal Vegetation

Finn Danielsen, Mikael K. Sørensen, Mette F. Olwig, Vaithilingam Selvam, Faizal Parish, Neil D. Burgess, Tetsuya Hiraishi, Vagarappa M. Karunagaran, Michael S. Rasmussen, Lars B. Hansen, Alfredo Quarto, and Nyoman Suryadiputra
Science 28 October 2005: 643.
India's coastline areas with intact mangrove forest or Casuarina trees suffered less damage from the 26 December 2004 tsunami than did unprotected areas. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

Scott A. Tomlins, Daniel R. Rhodes, Sven Perner, Saravana M. Dhanasekaran, Rohit Mehra, Xiao-Wei Sun, Sooryanarayana Varambally, Xuhong Cao, Joelle Tchinda, Rainer Kuefer, Charles Lee, James E. Montie, Rajal B. Shah, Kenneth J. Pienta, Mark A. Rubin, and Arul M. Chinnaiyan
Science 28 October 2005: 644-648.
Most human prostate cancers show a previously unknown gene rearrangement that makes them grow in response to male hormones, a mechanism that may also apply to other cancers. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Hanbury Brown Twiss Effect for Ultracold Quantum Gases

M. Schellekens, R. Hoppeler, A. Perrin, J. Viana Gomes, D. Boiron, A. Aspect, and C. I. Westbrook
Science 28 October 2005: 648-651.
Published online 15 September 2005 [DOI: 10.1126/science.1118024] (in Science Express Reports)
Correlations between atoms in nondegenerate and degenerate bosonic quantum gases exhibit behavior resembling that seen in their optical analogs, thermal and coherent emitters. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Quantum Coherence in an Optical Modulator

S. G. Carter, V. Birkedal, C. S. Wang, L. A. Coldren, A. V. Maslov, D. S. Citrin, and M. S. Sherwin
Science 28 October 2005: 651-653.
A quantum dot can modulate light at terahertz frequencies, potentially increasing the information content carried in optical communication. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Dating the Growth of Oceanic Crust at a Slow-Spreading Ridge

Joshua J. Schwartz, Barbara E. John, Michael J. Cheadle, Elena A. Miranda, Craig B. Grimes, Joseph L. Wooden, and Henry J. B. Dick
Science 28 October 2005: 654-657.
Dates on the magmas that form new oceanic crust show that many are older than the presumed age of the crust and may represent remobilized deeper material. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Role of Land-Surface Changes in Arctic Summer Warming

F. S. Chapin, III, M. Sturm, M. C. Serreze, J. P. McFadden, J. R. Key, A. H. Lloyd, A. D. McGuire, T. S. Rupp, A. H. Lynch, J. P. Schimel, J. Beringer, W. L. Chapman, H. E. Epstein, E. S. Euskirchen, L. D. Hinzman, G. Jia, C.-L. Ping, K. D. Tape, C. D. C. Thompson, D. A. Walker, and J. M. Welker
Science 28 October 2005: 657-660.
Published online 22 September 2005 [DOI: 10.1126/science.1117368] (in Science Express Reports)
The longer snow-free season in Alaska increases energy absorption from the Sun, contributing as much to arctic warming as do rising greenhouse gas levels. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Ordered Liquid Aluminum at the Interface with Sapphire

S. H. Oh, Y. Kauffmann, C. Scheu, W. D. Kaplan, and M. Rühle
Science 28 October 2005: 661-663.
Published online 6 October 2005 [DOI: 10.1126/science.1118611] (in Science Express Reports)
The crystalline ordering of a ceramic substrate influences the structure of molten metal droplets lying upon it. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Stem-Cell Homeostasis and Growth Dynamics Can Be Uncoupled in the Arabidopsis Shoot Apex

G. Venugopala Reddy and Elliot M. Meyerowitz
Science 28 October 2005: 663-667.
Published online 6 October 2005 [DOI: 10.1126/science.1116261] (in Science Express Reports)
A single signaling factor regulates cells at the tip of the growing plant shoot, separately controlling their number and identities. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Antagonistic Actions of Ecdysone and Insulins Determine Final Size in Drosophila

Julien Colombani, Laurence Bianchini, Sophie Layalle, Emilie Pondeville, Chantal Dauphin-Villemant, Christophe Antoniewski, Clément Carré, Stéphane Noselli, and Pierre Léopold
Science 28 October 2005: 667-670.
Published online 22 September 2005 [DOI: 10.1126/science.1119432] (in Science Express Reports)
The insect steroid hormone ecdysone coordinates growth, maturation, and final organism size by regulating insulin action through the larval fat body. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Small-Molecule Inhibitor of Vibrio cholerae Virulence and Intestinal Colonization

Deborah T. Hung, Elizabeth A. Shakhnovich, Emily Pierson, and John J. Mekalanos
Science 28 October 2005: 670-674.
Published online 13 October 2005 [DOI: 10.1126/science.1116739] (in Science Express Reports)
A small molecule found in a screen for agents that block expression of the cholera toxin gene prevents cholera infection in mice by interfering with colonization of the gut by Vibrio cholerae. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

The V-Antigen of Yersinia Forms a Distinct Structure at the Tip of Injectisome Needles

Catherine A. Mueller, Petr Broz, Shirley A. Müller, Philippe Ringler, Françoise Erne-Brand, Isabel Sorg, Marina Kuhn, Andreas Engel, and Guy R. Cornelis
Science 28 October 2005: 674-676.
Antibodies that protect against the plague act on a protein that forms the tip of a "needle" through which the plague bacterium injects pathogenic factors into the host. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Bats Are Natural Reservoirs of SARS-Like Coronaviruses

Wendong Li, Zhengli Shi, Meng Yu, Wuze Ren, Craig Smith, Jonathan H. Epstein, Hanzhong Wang, Gary Crameri, Zhihong Hu, Huajun Zhang, Jianhong Zhang, Jennifer McEachern, Hume Field, Peter Daszak, Bryan T. Eaton, Shuyi Zhang, and Lin-Fa Wang
Science 28 October 2005: 676-679.
Published online 29 September 2005 [DOI: 10.1126/science.1118391] (in Science Express Reports)
Several species of bat living in China are natural hosts of coronaviruses closely related to those responsible for the SARS outbreak. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Neurogenesis in the Hypothalamus of Adult Mice: Potential Role in Energy Balance

Maia V. Kokoeva, Huali Yin, and Jeffrey S. Flier
Science 28 October 2005: 679-683.
A growth factor that allows obese mice to regulate their body weight normally acts by generating new neurons in the feeding center of the brain. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates

Serge Luquet, Francisco A. Perez, Thomas S. Hnasko, and Richard D. Palmiter
Science 28 October 2005: 683-685.
Unlike adults, infant mice do not starve when neurons in the feeding center of their brains are removed, presumably because circuits are rewired. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|