SCIENCE CAREERS: Managing Scientists

Karyn Hede
Science 9 November 2007: 993-995.
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SCIENCE CAREERS: Toward a Philosophy of Resource Management

Siri Carpenter
Science 9 November 2007: 994-995.
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This Week in Science

Editor summaries of this week's papers.
Science 9 November 2007: 883.
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Editorial:
Bill Golden

Donald Kennedy
Science 9 November 2007: 887.
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Editors' Choice

Highlights of the recent literature.
Science 9 November 2007: 888.
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Science Podcast

Science 9 November 2007: 991.
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News of the Week

ASTROPHYSICS: Universe's Highest-Energy Particles Traced Back to Other Galaxies

Adrian Cho
Science 9 November 2007: 896-897.
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RESEARCH CAREERS: Postdoc Survey Finds Gender Split on Family Issues

Yudhijit Bhattacharjee
Science 9 November 2007: 897.
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NEUROSCIENCE: Spying On New Neurons in the Human Brain

Greg Miller
Science 9 November 2007: 899-900.
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NEUROSCIENCE: Hippocampal Cells Help Rats Think Ahead

Karen Heyman
Science 9 November 2007: 900.
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TUBERCULOSIS: Few Mutations Divide Some Drug-Resistant TB Strains

Robert Koenig
Science 9 November 2007: 901-902.
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SCIENCE IN CHINA: Max Planck's Asian Venture Rethinks Its Agenda

Richard Stone
Science 9 November 2007: 902.
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EVOLUTIONARY GENOMICS: Fruit Fly Blitz Shows the Power of Comparative Genomics

Elizabeth Pennisi
Science 9 November 2007: 903.
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ScienceScope

Science 9 November 2007: 899.
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Random Samples

Science 9 November 2007: 893.
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Newsmakers

Science 9 November 2007: 895.
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News Focus

MICHAEL WALKER: Seeking Nature's Inner Compass

John Bohannon
Science 9 November 2007: 904-907.
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MICHAEL WALKER: A Home for Maori Science

John Bohannon
Science 9 November 2007: 907.
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PLANETARY SCIENCE: Majority Rules in Finding a Path for the Next Mars Rover

Richard A. Kerr
Science 9 November 2007: 908-909.
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GENETICS: Who's the Queen? Ask the Genes

John Whitfield
Science 9 November 2007: 910-911.
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Letters

This Week's Letters

Science 9 November 2007: 913.
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 Speaking Out About U.S. Science Output

John P. Moore;, Rickye S. Heffner;, and Stephen W. Director
Science 9 November 2007: 913.
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 Threats to Privacy Protection

Carol Isaacson Barash
Science 9 November 2007: 913-914.
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 Potent Questions About India's Polio Vaccine

Subhash C. Arya, Nirmala Agarwal;, Nicholas C. Grassly, Jay Wenger, and R. Bruce Aylward
Science 9 November 2007: 914-916.
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 Corrections and Clarifications

Science 9 November 2007: 914.
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Books et al.

SOCIAL SCIENCES: Arguing for Computational Power

Daniel Diermeier
Science 9 November 2007: 918-919.
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EVOLUTION AND BEHAVIOR: Simple Maths for a Perplexing World

Daniel J. Rankin
Science 9 November 2007: 919.
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Policy Forum

ENVIRONMENTAL SCIENCE: Rethinking Desalinated Water Quality and Agriculture

U. Yermiyahu, A. Tal, A. Ben-Gal, A. Bar-Tal, J. Tarchitzky, and O. Lahav
Science 9 November 2007: 920-921.
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Perspectives

ASTRONOMY: Mixing a Stellar Cocktail

Corinne Charbonnel and Suzanne Talon
Science 9 November 2007: 922-923.
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MATERIALS SCIENCE: How Does Radiation Damage Materials?

Brian D. Wirth
Science 9 November 2007: 923-924.
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CHEMISTRY: Enhancing Colloids Through the Surface

Erik C. Nelson and Paul V. Braun
Science 9 November 2007: 924-925.
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CELL SIGNALING: mTOR, Unleashed

Christopher G. Proud
Science 9 November 2007: 926-927.
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COMPUTER SCIENCE: Is There Progress on Talking Sensibly to Machines?

Yorick Wilks
Science 9 November 2007: 927-928.
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PHYSIOLOGY: An Integrative View of Obesity

Brent E. Wisse, Francis Kim, and Michael W. Schwartz
Science 9 November 2007: 928-929.
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Review

A General Model of Prion Strains and Their Pathogenicity

John Collinge and Anthony R. Clarke
Science 9 November 2007: 930-936.
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Brevia

A Cretaceous Hoofed Mammal from India

G. V. R. Prasad, O. Verma, A. Sahni, V. Parmar, and A. Khosla
Science 9 November 2007: 937.
A fossil tooth implies that early ungulates, which otherwise appear after the end-Cretaceous extinction, existed in India while it was adrift from other continents. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Research Articles

Correlation of the Highest-Energy Cosmic Rays with Nearby Extragalactic Objects

The Pierre Auger Collaboration
Science 9 November 2007: 938-943.
The source directions of the most energetic cosmic rays correlate with locations of nearby active galactic nuclei, implying that they form from supermassive black holes. Abstract »|   Full Text »|   PDF »|   Authors' Summary »|  

IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response

Jonathan H. Lin, Han Li, Douglas Yasumura, Hannah R. Cohen, Chao Zhang, Barbara Panning, Kevan M. Shokat, Matthew M. LaVail, and Peter Walter
Science 9 November 2007: 944-949.
When misfolded proteins accumulate within the endoplasmic reticulum, protective responses are initiated but prolonged stress ultimately triggers cell death pathways. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  Authors' Summary »|  

Reports

The Simplest Double Slit: Interference and Entanglement in Double Photoionization of H₂

D. Akoury, K. Kreidi, T. Jahnke, Th. Weber, A. Staudte, M. Schöffler, N. Neumann, J. Titze, L. Ph. H. Schmidt, A. Czasch, O. Jagutzki, R. A. Costa Fraga, R. E. Grisenti, R. Díez Muiño, N. A. Cherepkov, S. K. Semenov, P. Ranitovic, C. L. Cocke, T. Osipov, H. Adaniya, J. C. Thompson, M. H. Prior, A. Belkacem, A. L. Landers, H. Schmidt-Böcking, and R. Dörner
Science 9 November 2007: 949-952.
The angular pattern resulting when both electrons are ejected from H₂ implies that, as their energies become comparable, their behavior changes from wavelike to particle-like. Abstract »|   Full Text »|   PDF »|  

Accelerated Uplift and Magmatic Intrusion of the Yellowstone Caldera, 2004 to 2006

Wu-Lung Chang, Robert B. Smith, Charles Wicks, Jamie M. Farrell, and Christine M. Puskas
Science 9 November 2007: 952-956.
Satellite radar and GPS measurements indicate that the central Yellowstone has been rising by 7 centimeters per year since 2004, implying that magma is intruding below. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Observation of the One-Dimensional Diffusion of Nanometer-Sized Dislocation Loops

K. Arakawa, K. Ono, M. Isshiki, K. Mimura, M. Uchikoshi, and H. Mori
Science 9 November 2007: 956-959.
Even under no external stress, a loop of defects in iron can diffuse in one direction, at a rate depending on its size, as double kinks in the iron lattice form stochastically. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

One-Dimensional Fast Migration of Vacancy Clusters in Metals

Yoshitaka Matsukawa and Steven J. Zinkle
Science 9 November 2007: 959-962.
Observations of radiation-damaged gold foils show that clusters of 100 or more vacancies migrate faster in one dimension than a single vacancy does via a random walk. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Widespread Morning Drizzle on Titan

Máté Ádámkovics, Michael H. Wong, Conor Laver, and Imke de Pater
Science 9 November 2007: 962-965.
Published online 11 October 2007 [DOI: 10.1126/science.1146244] (in Science Express Reports)
Infrared mapping of the atmosphere of Saturn’s moon Titan suggests that small methane droplets that form each morning help cycle methane between the atmosphere and surface. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Facultative Mate Choice Drives Adaptive Hybridization

Karin S. Pfennig
Science 9 November 2007: 965-967.
Female spadefoot toads are more likely to choose mates of another species when such behavior may increase offspring survival. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Bypass of DNA Lesions Generated During Anticancer Treatment with Cisplatin by DNA Polymerase

Aaron Alt, Katja Lammens, Claudia Chiocchini, Alfred Lammens, J. Carsten Pieck, David Kuch, Karl-Peter Hopfner, and Thomas Carell
Science 9 November 2007: 967-970.
A specialized polymerase successfully replicates damaged DNA by partially compensating for distortion of the helix introduced by the lesion. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

GNAT-Like Strategy for Polyketide Chain Initiation

Liangcai Gu, Todd W. Geders, Bo Wang, William H. Gerwick, Kristina Håkansson, Janet L. Smith, and David H. Sherman
Science 9 November 2007: 970-974.
An enzyme in cyanobacteria that unexpectedly acts as an S-acetyltransferase and catalyzes decarboxylation can be used for synthesis of an anticancer polyketide. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

A Bifunctional Bacterial Protein Links GDI Displacement to Rab1 Activation

Matthias P. Machner and Ralph R. Isberg
Science 9 November 2007: 974-977.
Published online 18 October 2007 [DOI: 10.1126/science.1149121] (in Science Express Reports)
The bacterium that causes Legionnaires’ disease recruits a host protein that regulates vesicle trafficking by mimicking host-activating proteins. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38

Xiaochun Bai, Dongzhu Ma, Anling Liu, Xiaoyun Shen, Qiming J. Wang, Yongjian Liu, and Yu Jiang
Science 9 November 2007: 977-980.
Nutrients turn on a regulator of cell growth and proliferation by displacing an inhibitor of the regulator’s kinase activity with a small guanosine triphosphatase. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain

Louis N. Manganas, Xueying Zhang, Yao Li, Raphael D. Hazel, S. David Smith, Mark E. Wagshul, Fritz Henn, Helene Benveniste, Petar M. Djuric, Grigori Enikolopov, and Mirjana Maletic-Savatic
Science 9 November 2007: 980-985.
A fatty acid found only in neural progenitor cells can be monitored by NMR spectroscopy in living humans to show that neurogenesis in the hippocampus decreases with age. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Sex-Linked Genetic Influence on Caste Determination in a Termite

Yoshinobu Hayashi, Nathan Lo, Hitoshi Miyata, and Osamu Kitade
Science 9 November 2007: 985-987.
Assignment of termites to sterile worker or reproductive castes, previously thought to be determined solely by environmental conditions, has a critical genetic component. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Mnemonic Function of the Dorsolateral Prefrontal Cortex in Conflict-Induced Behavioral Adjustment

Farshad A. Mansouri, Mark J. Buckley, and Keiji Tanaka
Science 9 November 2007: 987-990.
Published online 25 October 2007 [DOI: 10.1126/science.1146384] (in Science Express Reports)
Dorsolateral prefrontal cortex but not anterior cingulate cortex is essential for conflict-induced behavioral adjustment. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"

Christopher A. Johnston, Brenda R. Temple, Jin-Gui Chen, Yajun Gao, Etsuko N. Moriyama, Alan M. Jones, David P. Siderovski, and Francis S. Willard
Science 9 November 2007: 914.
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Response to Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"

Xigang Liu, Yanling Yue, Wei Li, and Ligeng Ma
Science 9 November 2007: 914.
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